1.Investigation on hypertension and related risk factors among returning nationals in Zhangzhou city of Fujian
Chinese Journal of cardiovascular Rehabilitation Medicine 2013;22(4):334-338
Objective: To study epidemiological characteristics of hypertension in returning nationals and their offspring, and analyze its relative risk factors. Methods: A total of 1 278 returning nationals were randomly selected as nationals group, and 1 267 local residents were regard as local residents group. All subjects received questionnaire and physical examination. Multifactor logistic regression analysis was used to analyze relative risk factors. Results: Incidence rate of hypertension was 19.25% in nationals group (standardized rate was 16.23%), which was significantly higher than 13.10% of local residents group (standardized rate was 11.04%) (χ2=17.72, P<0.01). As age increased, incidence rate of hypertension showed an increasing trend, which started to significantly rise in 30~ years group. Multi-factor Logistic regression analysis indicated that factors entered equation were gender, age, alcohol drinking, high-fat diet, dyslipidemia, body mass index, genetic factor and exercises, and their OR values were 1.76, 2.37, 3.62, 2.98, 1.86, 3.15, 3.12 and 2.74 respectively. Conclusion: Incidence rate of hypertension in returning nationals is significantly higher than that of local residents. Incidence rate of hypertension of returning nationals showed an increasing trend. Their risk factors were age, alcohol drinking, high-fat diet, dyslipidemia, body mass index, genetic factor and exercises etc.
2.Investigation on Clonorchis sinensis infection and its risk factors in Futian District,Shenzhen City
Suyun FAN ; Xianghui SHI ; Jifei NIU ; Zhiping LIN ; Lilian LI
Chinese Journal of Schistosomiasis Control 2014;(6):699-700
Objective To understand the status of Clonorchis sinensis infection and its risk factors in Futian District Shen?zhen City so as to provide the evidence for formulating the strategy of prevention and control. Methods Two monitoring points were randomly selected and the permanent population aged≥3 years were investigated and their stool samples were detected for the eggs of C. sinensis by using Kato?Katz technique. Meanwhile the risk factors of infection were also investigated. Results A total of 743 subjects were examined and 7 persons were infected with C. sinensis and the infection rate was 0.94%. Most of the infected cases were focused on 20?40 and 40?60 age groups. The risk factors were eating raw or semi?cooked fish and the protec?tive factor was the use of separated cutting board for cooked or uncooked food. Conclusion The infection rate of C. sinensis is low in the population of Futian District. However the health education especially for diet health education still should be strengthened.
3.Correlation study of multi-slice spiral CT perfusion imaging in liver cirrhosis and portal morphology
Ping XIAO ; Mingwu LOU ; Lilian TAN ; Yangbin LI ; Yong LI ; Li GAO ; Huanxing LIN
Journal of Chinese Physician 2009;11(5):606-608
Objective To discuss correlation of hemodynamic changes and portal vein diameter with multi-slice spiral CT peffusion imaging in liver cirrhosis. Method 31 cases liver cirrhosis were enrolled in this study. The first porta hepatis were selected for target lay of CT perfusion scan. Liver perfusion parameters were obtained by color perfusion map method. Right to left diameter and occipitofrontal diame-ter of portal vein were measured. 30 cases of normal persons were used as control group. Result Hepatic arterial perfusion (HAP) in liver 0.05). Hepatic perfusion index (HPI) were (19.13±3.33)% and (20.61±8.56)%, which had no statistically significant difference with the other two groups (P>0.05). Conclusion Multi-spiral CT perfnsion imaging is an effectively noninvasive method to evaluate the hemodynamic changes of liver cirrhosis. Occipitofrontal diameter of portal vein with liver cirrhosis can reflect the state of liver hemodynamics.
4.Differentiating Acute Benign Vertebral Fractures from Vertebral Metastasis by Combining Quantification Analysis of Dual Echo Technique with Apparent Diffusion Coefficient
Fan LIN ; Yi LEI ; Yangbin LI ; Lilian TAN ; Ke LIU ; Zhiming LI
Journal of Practical Radiology 2009;25(12):1785-1789,1813
Objective To evaluate the value of dual echo technique in combination with apparent diffusion coefficient(ADC) in differentiating acute benign vertebral fracture from metastasis.Methods 43 patients (mean age, 68.2 years) with 79 metastatic vertebrae and 59 patients(mean age,60) with 68 acute vertebral fractures were included in our study.The slices of largest size of lesion on T1WI were selected to measure and calculate the signal intensity ratio(SIR) and ADC of lesions.The difference of ADC values and SIR between benign acute vertebral fractures and vertebral metastasis were compared.Parallel test,serial test and receiver operating characteristic curve(ROC) analysis of logistic model were done.Results ADC values of metastasis and acute benign fracture were (1.32±0.5)×10~(-3)mm~2/s and (2.39±0.4)×10~(-3)mm~~2/s respectively,and SIR of them were 1.00±0.01 and 0.85±0.01 respectively,there were significantly different between these two entities with the two tests(P<0.05).The area under the curve(AUC) for SIR was 0.897 and for ADC was 0.960,there is significantly different between these two tests in AUC(P=0.02).When 0.97 as cut off value for SIR,the sensitivity and specificity were 84.81% and 76.47%% respectively,when 1.87×10~(-3)mm~2/s as cutoff value for ADC , the sensitivity and specificity were 93.67% and 91.18% respectively . The sensitivity and specificity were 99.04% and 69.73% respectively in the parallel tests and 79.44%,97.92% in the serial test.A combining predictor established with logistic regression model showed a high AUC:0.985,which was higher than that of ADC and SIR alone.The AUC under ROC for ADC was significantly larger than that of SIR . When 0.55 as cut off value for this combining predictor , the sensitivity and specificity were 98.73% and 95.59% respectively.Multiple comparisons were performed with LSD-t test :combining predictor>ADC>SIR,it showed that there was significantly different between indexes(P<0.05). Conclusion ADC in combination with SIR can improve the effects in differentiating benign acute vertebral fractures and vertebral metastasis.
5.The Relationship between the Extent of Red Color on Pseudocolor CT Image and MVD in Lung Carcinoma
Lilian TAN ; Mingjun HAN ; Zhiming LI ; Lin YU ; Jindai JIANG ; Shuxin LI
Chinese Journal of Medical Imaging 2009;(6):405-408
Purpose:To discuss the relationship between the extent of red pseudocolor of pseudocolor CT image and MVD in lung carcinoma.Materials and Methods: The CT angiography was performed by using 16-slices spiral CT in 25 cases with pulmonary carcinoma,proved by pathology.Pseudocolor VR of tumor lesions of pulmonary carcinoma was performed.The immunohistochemical test of MVD of tumor lesion of pulmonary carcinoma was performed in 25 cases.The relation between the extent of red color on pseudo color VR and MVD of tumor lesion of pulmonary carcinoma were analyzed.Results: The extents of red pseudocolor of tumor lesion on VR pseudocolor Imaging were divided to four types: heavy ( n = 5 ),moderate ( n - 8 ),light (n = 9 ),no color( n = 3 ).The add CT values of tumor lesion after enhanced CT were 26.32 ±9.17Hu in 13 cases with heavy or moderate group,10.87 ±4.257Hu in 12 cases with light or no red color group.The numbers of MVD of tumor lesion of pulmonary carcinoma were 57 ±6.43 in 13 cases with heavy or moderate group,19 ±5.29 in 12 cases with light or no red color group.The numbers of MVD of pulmonary carcinoma had statistical significant between heavy or moderate group and light or no red color group.Conclusion:It has a significantly direct correlation between the extent of red pseudocolor of tumor lesion on pseudocolor image and MVD of tumor lesion in pulmonary carcinoma.
6.Analysis of the effects of the combination of PBL and multimedia network teaching model in the preclinical course of image diagnostics
Xi LI ; Xiaohong BI ; Qinmei LI ; Lin YU ; Yu WEN ; Lilian TAN ; Deji CHEN
Chinese Journal of Medical Education Research 2016;15(7):750-754
Objective To investigate the effect of the courses of image diagnostics on clinical pro-bation period via the combination of PBL and multimedia network teaching model. Methods 126 under-graduates from the department of medical image (Grade 2011 and 2012) were selected as teaching subjects, and PBL combined with multimedia network teaching was adopted in the teaching of the course of medical imaging diagnosis. After class we implemented a questionnaire survey, and let the students write learning experience. Statistical analysis was conducted by using SSPS 13.0 to reflect the teaching participation in the students' questionnaire and a. summary analysis of the learning experience of the students was also made. Results 123 valid questionnaires were collected. 94.31%(116 people) of students were active participants in these courses, 90.25%(111 people) of the students thought they could actively communicate in teaching, and 43% (110 people) of the students thought they got fully prepared before class. 123 articles in accor-dance with the requirements of experience were received; most students took positive attitude to the active influence the teaching methods had brought; some student pointed out that the teaching method had the disadvantages such as too much time to prepare, too much information, and so on. Conclusions The com-bination of PBL and multimedia network teaching has preliminary results. It is a novel model that is available for teaching image diagnostics on clinical probation period.
7.The evaluation of cardiac function in coronary heart disease with stress myocardial perfusion imaging using 320-slice spiral CT
Zhiming LI ; Xianyue QUAN ; Lilian TAN ; Shuxin LI ; Yong HUANG ; Lin YU
Journal of Practical Radiology 2014;(7):1129-1132
Objective To explore the application value of 320-slice spiral CT myocardial perfusion technique in the evaluation of cardiac function in patients with coronary artery disease.Methods 24 patients with known reversible myocardial ischemia with coro-nary heart disease and 13 cases of normal were detected by 320-slice spiral CT myocardial perfusion scan in resting and after dobu-tamine-induced stress,measured the values of cardiac function indexes(ESV、EDV、SV、EF)in resting and after dobutamine-induced stress respectively,the results were analyzed by paired t test and independent sample t test,when the P value is less than 0.05,con-sidered statistically significant or correlation.Results The values of cardiac function indexes (ESV,EDV,SV)between the resting and after dobutamine-induced stress were significantly different except EF value in normal group.But only the EF value was signifi-cantly different in CHD,the rest values of cardiac function indexes(ESV,EDV,SV)no significant difference.Each corresponding value of cardiac function indexes in resting and after dobutamine-induced stress was significantly different between the CHD and the normal.Conclusion The dobutamine-induced stress myocardial perfusion with 320-slice spiral CT can judge the impaired degree of cardiac function in patients with myocardial ischemia,provide the basis for comprehensive evaluation of coronary artery disease and its prognosis.
8.The effect of zoledronic acid on osteoporotic intertrochanteric fractures
Quan JI ; Lilian ZHAO ; Lei SHI ; Liang ZHANG ; Lin WANG ; Liangyuan WEN ; Qingyun XUE
Chinese Journal of Orthopaedics 2014;34(1):29-32
Objective To compare of the effect of intravenous zoledronic acid and calcitonin on the elderly with osteoporotic intertrochanteric fractures.Methods From June 2009 to November 2012,610 patients with osteoporotic intertrochanteric fractures were treated with closed reduction and internal fixation.543 consecutive patients were grouped sequentially according to the admission time.From June 2009 to April 2011,control group (n=325)received calcitonin for osteoporosis (male 107,female 218,mean age 75.02±5.65 years).The number of Evans-Jensen type Ⅰ,Ⅱ,and Ⅲ type patients were 87,136,and 102,respectively.Average lumbar bone mineral density (BMD) and hip BMD were 0.737±0.08 g/cm2 and 0.725±0.05 g/cm2,respectively.From May 2011 to November 2012,218 patients (male 82,female 136,mean age 74.71±5.32 years) received zoledronic acid for osteoporosis.The number of Evans-Jensen type Ⅰ,Ⅱ,and Ⅲ type patient were 62,91 and 65,respectively.Average lumbar BMD and hip BMD were 0.738±0.05 g/cm2 and 0.722±0.06 g/cm2,respectively.All patients received once-yearly intravenous zoledronic acid in one week after operation.The BMD during hospitalization and one year after operation were compared between the two groups.Harris score and VAS score were applied to evaluate the function and pain degree of the operated hip joint.Results The average follow-up time were 12.8 months (range,5 to 22 months) in control group and 12.5 months (range,4 to 19 months) in treatment group.The average fracture union time,Harris score,VAS score were 14.25±1.38 weeks,68.88±5.71 points,and 0.36±0.55 points respectively in treatment group and 14.39± 1.12 weeks,69.47±4.60 points,and 0.33±0.48 points respectively in control group.There were no statistical differences between two groups in fracture union time,Harris score and VAS score.The average lumbar BMD and hip BMD were 0.76±0.06 g/cm2 and 0.75±0.04 g/cm2 in treatment group,which were 0.75±0.07 g/cm2 and 0.74± 0.07 g/cm2 in control group one year after operation,respectively.Compared with the baseline,the BMD of lumbar spine and hip one year after operation slightly increased without statistically significant difference in control group.The BMD increased significantly in treatment group.Conclusion Early administration of intravenous zoledronic acid does not influence bone healing and it could increase BMD one year after closed reduction and internal fixation.
9.Analysis of carrying status and drug susceptibility of Streptococcus agalactiae in genital tract of pregnant women
Aixin LIN ; Chunlei YUAN ; Weishan WANG ; Nan TAN ; Xiaohua YANG ; Lilian LI
International Journal of Laboratory Medicine 2014;(23):3220-3221
Objective To understand the carrying status and drug resistance of streptococcus agalactiae in the genital tract of pregnant women.Methods The vaginal discharge from pregnant women was collected for conducting the bacterial culture.The iso-lated streptococcus agalactiae was performed the identification and the drugs susceptibility test by the VITEK 2 fully automatice bacterial identification analyzer.Results Among 1 042 samples,streptococcus agalactiae was isolated in 6 cases with the separation rate of 5.4%.The drug sensitivity test showed the Streptococcus agalactiae was highly sensitive to penicillin,cefazolin,vancomycin, linezolid and nitrofurantoin.The intermediate strains or drug resistant strains were not found.The sensitive rate to levofloxacin, moxifloxacin and clindamycin,erythromycin,tetracycline were 84.0%,84.0%,71.4%,39.3% and 8.9% respectively.Conclusion The carrying rate of streptococcus agalactiae in pregnant women is not high in our hospital.Penicillin and cefazolin should be as the drug of first choice for therapy and the clincal and laboratory nould payattention to detection of streptococcus agalactiae in pregnant women.
10.The effects of breastfeeding within 2 weeks after birth on late-onset sepsis in very low birth weight infants
Huiyan WANG ; Xiaoyun XIONG ; Xueyu CHEN ; Chuanzhong YANG ; Lilian CHEN ; Bingchun LIN ; Chun CHEN
Chinese Journal of Neonatology 2022;37(3):198-202
Objective:To study the effects of breastfeeding within 2 weeks after birth on late-onset sepsis in very low birth weight infants (VLBWI).Methods:From July 2018 to June 2019, clinical data of VLBWI (birth weight <1 500 g) born in our hospital were retrospectively reviewed. According to the proportion of breastfeeding volume in total feeding volume within 2 weeks after birth, the infants were assigned into high-proportion breastfeeding group (breastfeeding >50%), low-proportion breastfeeding group (breastfeeding ≤50%) and formula group. The incidences of late-onset sepsis among the three groups were compared using the chi-square test or Fisher's exact probability method. Logistic regression was used to analyze the effects of breastfeeding within 2 weeks after birth on late-onset sepsis.Results:The incidences of late sepsis in high-proportion breastfeeding group, low-proportion breastfeeding group and formula group were 0.4% (1/216), 8.1% (5/62) and 8.0% (2/25), respectively ( P<0.001). Logistic regression analysis showed that compared with the high-proportion breastfeeding group, the low-proportion breastfeeding group ( OR=17.844, 95% CI 2.005~158.775) and the formula group ( OR=23.261, 95% CI 1.916~282.350) had increased risks of late-onset sepsis. Conclusions:For VLBWI, high proportion breastfeeding (breastfeeding >50%) within 2 weeks after birth may reduce the risk of late-onset sepsis.