ABSTRACT Atherosclerosis (AS) is the principle cause of cardiovascular disease. For many years, AS was regarded as irreversible. However, recent accumulated evidence suggests that AS can regress with proper manipulation. Studies from animal models show that low cholesterol diet can induce obvious regression of AS plaques; Drugs, such as probucol, clolestyramine, lovastatin, isradipine, fosinopril, etc, can reverse the AS respectively by manipulating plasma lipoprotein, scavenging free radicals, blocking calcium channel or inhibiting an-giotensin converting enzyme. Clinical trials furthersubstantiate that good lifestyle and effective control of plasma lipoprotein can reduce clinical events and cause AS plaques regression. Although, AS plaques can regress is no longer in doubt, the mechanism is still unknown. The HDL-mediated reverse cholesterol transport system, apoptosis of the plaque cells may play an important role.

Objective To explore the characteristics of childhood tuberculosis and recent advances in the diagnosis and treatment of this disease in order to improve its diagnosis and treatment. Methods Key words“child”“tuberculosis”“diagno-sis” and “treatment” were used to retrieve relevant literatures from Pubmed,Web of Science,CNKI and Wanfang databases.The literatures were reviewed and clinical experience summarized. Results Disseminated tuberculosis and extrapulmonary tubercu-losis were common in children with tuberculosis. It was difficult to collect with samples of diagnostic value for detection. There counterparts were no systematic diagnosis and treatment programs available for children with drug-resistant tuberculosis,and phar-maceutical dosage forms tailored for children were lacking. Conclusion Tuberculosis in children is more complex to diagnose and treat than in adult counterpart.Diagnosis of this disease relies on a variety of diagnostic methods.It's still challenging to control childhood tuberculosis.

Objective To evaluate the clinical value of application of mesh plug tension-free repair of ingui-nal hernia in grass-roots hospital .Methods A total of 32 patients with inguinal hernia treated by benison-free ingui-nal herniorrhaphy with mesh plug and 28 patients treated with the traditional herniorrhaphy were retrospectively ana-lysed.Results The mean operation time and the postoperative hospital stay of group A were 56.94min and 5.25d, and those of group B were 69.61min and 5.96d,the mean operation time and the postoperative hospital stay of group A were significantly shorter than those of group B (t=-2.891、-3.284,all P<0.05).Patients needed postoperative analgesic therapy (10 cases) and patients suffered from urine retation ( 2 cases ) of group A were less than group B(χ2 =8.014,5.357,all P<0.05).There were 3 cases with postoperative scrotum hematoma in each group and they had no statistical difference for that(P>0.05).All cases received follow-up for 20-40 months,there were no recur-rence in group A during the follow-up period,but 2 cases recurrence in group B .Conclusion Mesh plug tension-free repair of inguinal hernia has the advantages of shorter operation time ,more rapid recovery ,less complications and low-er recurrence rate ,so it is suitable for popularization and application in grass-roots hospital .

Objective To know the status of disinfection conducted in the hospitals at province level in Hunan province aimed to make the intervention strategy for prevention and control of diseases transmission. Methods The related items of hospitals at province level were examined and evaluated according to the national standards such as GB15982-1995 Hygienic Standard for Disinfection in Hospital, GB15981-1995 Evaluating Method and Standard for the Efficacy of Disinfection and Sterilization, GB8987-1996 Requirements for Hospital Sewage Discharge, GB18466-2001 Requirements for Medical Organization Sewage Discharge, GB15980-1995 Hygienic Standard of Disinfection for Single Use Medical Products and Technical Standard for Disinfection (2002). Results As for the disinfection effect in the present investigation, the total qualified rate was 90.10%, the annual qualified rate was increasing. Conclusion The surveillance of hospital disinfection is a long-term task, to supervise and improve the hospital disinfection is necessary to ensure patient and society safety.

The first molar of youth is often extracted for seriously caries or without long term good effect after therapy because the first molar is often misunderstood as deciduous tooth by parents and therefore it is regarded as unnecessary to treat. For such young patients, the corresponding ipsilateral first molar caries while third molars (or germ) existing with crown well-developed,we can exact the first molar and move the second molar by segmental arch technique. In this way, we can quickly shift the second molar to the desired location, increases the efficiency and reduce both dental movement and period of treatment.

Objective To investigate the correlation between regional cerebral oxygen saturation (rSO2) value and the prognosis of comatose patients in the intensive care unit (ICU).Methods From January 2013 to September 2014, a total of 64 comatose patients admitted in the department of ICU were enrolled.The patients were divided into two groups : consciousness group (n =25) and coma group (n =39).The level of the Glasgow coma scale (GCS), APACHE Ⅱ score and Full Outline of UnResponsiveness score (FOUR) of patients were monitored.The rSO2 was measured by Somanetics INVOS 5100 monitor.Results The differences in levels of FOUR and GCS at admission and GCS at discharge between the two groups were statistically significant (P ＜ 0.05).In the consciousness group, the levels of GCS、 FOUR and rSO2 were higher compared with the coma group (P ＜ 0.05).ROC curve analysis revealed that the areas under the curve of GCS, FOUR and rSO2 for predicting prognosis were 0.823 (0.718-0.928), 0.820 (0.728-0.912) and 0.924 (0.863-0.985) respectively.Conclusions The rSO2 was useful for estimating the prognosis of comatose patients in general ICU.

The current situation of the satellite-based distant medical education, the distant hygienic education was introduced. We analysed the characteristic and advantage and indicated the importance and necessity of the satellite-based distant medical education.

With the development of communication techniques,the satcom telemedicine system is being applied more and more widely. Satellite communication is a means of communication of the broadest transmission scope and the largest coverage.The establishment of the satcom medicine system has effectively solved such bottleneck problems as date transmission block and network interrupt,The present article reviews the development of the satcom telecommunication system at home and abroad,the composition and characteristics of telecommunication,the composition and function of the PLA VSAT satcom telemedicine system,and the trend of development.

Objective: To design a set of digital medical record MIS. Methods: According to the problems of paper-based medical records management, the protocol of digital medical record MIS using micro-digital imaging technology was proposed. Results:It realized electronic medical record storage, the front page information of medical records, medical record circulation and statistics of medical information. Conclusion: The storage of paper based medical record was effectively compressed, the information level of medical record management was clearly promoted after using the digital medical record MIS. It realized the conservation and usage for current medical records, guaranteed information security and data sharing etc.

Objective:To investigate high sensitivity-C reactive protein (Hs-CRP) as a prognostic factor in non-Hodgkin lympho-ma (NHL). Methods:Data for 85 consecutive non-Hodgkin lymphoma patients were followed up and reviewed to determine the value of Hs-CRP relative to known prognostic parameters. Results:The progression-free survival (PFS) and overall survival (OS) times of pa-tients with pre-therapeutic baseline serum Hs-CRP levels of≥4 mg/L were shorter than those of patients with basal serum Hs-CRP lev-els of<4 mg/L (P>0.05). However, the post-therapeutic, early-to-mid serum Hs-CRP level was not significantly correlated with the OS and PFS times (P>0.05). Multivariate Cox regression analysis showed that the pre-therapeutic baseline serum Hs-CRP level may be an important prognostic parameter for the relapse and survival of NHL patients (P<0.05). Conclusion:The baseline Hs-CRP level can be a major indicator of prognosis in NHL patients.