1.Investigation in psychological state and it's correlation factors of family members of dderly cancerpatients
Chinese Journal of Practical Nursing 2009;25(24):63-64
Objective To investigate the psychological state and its correlation factors of family members of elderly cancer patients. Methods A total of 76 family members of elderly cancer patients were investigated with questionnaires with Zung's self-rating anxiety scale (SAS) and self-rating depression scale (SDS). Their psychological state and its correlation factors were analyzed. Results Incidence rate of anxiety of elderly cancer patients' family members was 52.63%, and incidence rate of depression was 46.05%. The mean standard score of SAS and SDS of elderly cancer patients' family members were both significantly higher than domestic norm. Difference of family member's gender, ways to pay health care fee, pain degree and disease condition led to different SAS and SDS score. Conclusions Family members of elderly cancer patients possessed different degree of psychological obstacle which related with multiple factors. Medical staff should not only think highly of patients' psychological state, but also their family members'. And meanwhile they should take corresponding strategy to reduce the incidence rate of anxiety and depression state in those family members.
2.The Effects of Diazepam on Vestibular Compensation Following Unilateral Labyrinth injury
Chinese Journal of Trauma 1990;0(03):-
This report presents two cases of unilateral acute labyrinth loss resulted from injury,each showing delay in compensation possibly due to long-term administration of diazepam.The recent literature of the effects of the drugs onyestibular compensation is reviewed.The vestibular"suppressants"property of diazepam delays compensation when used on a long-term basis.However,it might be useful in controlling vege- tative symptoms and thereby possibly facilitate compensation when used on a short- tern basis.
3.Effects of psychological intervention on mental state and satisfaction of cosmetic plastic surgery
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(12):1115-1117
Objective To investigate the role of psychological intervention on cosmetic plastic surgery.Methods 600 cosmetic plastic surgery were collected from cosmetic plastic surgery of Jinan Military General Hospital,then randomly divided into control group(n=300) and study group (n=300) according to odd and even on the first visit.Conventional treatmentand care were applied to control group before,during and after operation.For study group,in addition to giving a general treatment and care,preoperative consultation talks were given to understand the beauty of the psychological characteristics,and motivations and expectations were given to adjust;music and psychological support were presented intraoperative; rehabilitation guidance were given after operation.Symptom checklist 90( SCL-90),general psychological problems of body image self-rating scale and postoperative satisfaction scale were used to assess the the mental state,body image question and satisfaction of plastic surgery.Results Before intervention,the scores of SCL-90 and the general body image self-rating scale were ( 187.5 ±52.61 ),(12.1 ± 2.2) in study group and (179.87 ± 53.33 ),(12.9 ± 2.0) in control group,there was no significant differences(P>0.05).After intervention,the scores of SCL-90 and the general body image self-rating scale ( 159.6 ± 31.3 ),(5.6 ± 0.5 ) in study group were lower than those in control group ( 167.4 ± 38.2 ),( 6.2 ±1.1 )(P < 0.01 ).Before and after treatment,50% reduced rate of 26%,25% reduced rate of 41.6%,body-negative rate of 97.1%,overall satisfaction rate of 89% of surgery in study group were higher than 14%,27.6%,84.3% and 53.67% in the control group,the differences were significant (P<0.01 ).Conclusion Psychological interventions can improve the psychological state,body image disturbance and operative satisfaction in cosmetic plastic surgery.Psychological interventions should pay more attention to irrmprove the efficacy of cosmetic plastic surgery.
4.The experience of the treatment of prostatic hyperplasia(BPH)with bladder calculus
Chinese Journal of Primary Medicine and Pharmacy 2012;19(2):211-212
Objective To evaluate the clinical effect and safety of ureteroscopic pneumatic lithotripsy combined with transurethral resection of prostate(TURP)for treatment of benign prostatic hyperplasia(BPH)with bladder calculus.Methods 68 patients of BPH with bladder calculus treated by ureteroscopic pneumatic lithotripsy combined with transurethral resection of prostate were reviewed.Results Satisfactory effects were achieved in all these 68 cases without serious complications.Conclusion Ureteroscopic pneumatic lithotripsy combined with TURP is a minimally invasive,safe and effective method in the treatment of BPH and bladder calculus.
5.Clinical Observation of Acupunture in Treating Depression and Effect on Serum Cell Factors
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
Objective To investigate the mechanism of acupuncture in anti-depression. Methods 100 depressive patients were randomly divided into acupuncture group and Amitriptyline group, 50 cases in each group. They were respectively treated by acupuncture at Neiguan (PC6), Sanyinjiao (SP6), Baihui (DU20), Fengchi (GB20), and oral western meicine. The needles were manipulated once every 20 minutes and treatment was given once a day. HAMD score and levels of serum cell factors of two groups were observed. Results Serum levels of interleukin 1? (IL-1?), interleukin-6 (IL-6) interleukin-2 (IL-2) and tumor necorsis factor-? (TNF-?) in depressive subjects before treatment were significanly higher than that of nomal subjects (all P
6.Preparation and purification of polyclonal antibodies against human Fc?/?R and the polymeric immunoglobulin receptor
Chinese Journal of Immunology 1985;0(01):-
Objective:To generate rabbit anti-human Fc?/?R and Poly Immunoglobulin Receptor(pIgR) polyclonal antibodies.Methods:The EC12 domain of human Fc?/?R and the D1 domain of pIgR were expressed as including bodies in Escherichia coli.The purified proteins were used to immunize rabbits to generate polyclonal antibodies.The immune sera were characterized by ELISA and Western blot analysis,then absorbed with cross-action and purified by antigen linked beads.Results:The titers of antiserum were 1∶6 4000 and 1∶25 6000,separately.There was little cross-reaction between the two immune sera.Conclusion:The polyclonal antibodies against human Fc?/?R and pIgR without cross-reaction were successfully generated and could be useful tools to study the relationship between the two receptors.
7.The Use of Psychological Intervention in Modified Electroconvulsive Therapy Patients
Journal of Medical Research 2006;0(05):-
Objective The purpose of the present study was to explore the use of psychological intervention in modified electroconvulsive therapy patients.Methods Divide all 160 patients random into two groups,the intervened group and the contrast group. The intervened group was accepted psychological intervention before the therapy day;The contrast group just did as normal.Record the anxiety, blood pressure,heart rate and the agreement to the therapy of the two group before the therapy.Results The anxiety of the intervened group was much little to the contrast group.The blood pressure and the heart rate of the intervened group was lower than the contrast group.Patient of the intervened group was much active to match with the treatment. Conclusions The use of psychological intervention in modified electroconvulsive therapy patients could decrease patient’s anxiety and painness,made them more active to match with the treatment.
8.Research progress of antiemetics in tumor therapy
Cancer Research and Clinic 2008;20(12):859-861
Chemotherapy plays a significant role in cancer therapy,but chemotherapy-induced nausea and vomiting(CINV)common happened and affects patients satisfaction with treatment.With the development ot physiology on emesis,the new antiemetics such as 5-HT3 receptor antagonist(5-HT3RA),Aprepitant and Olanzapine greatly improved the control of CINV,the guidelines for antiemeties were deftned.Research progress of antiemetics was summarized.
9.Clinical observation of fleabanein in treatment of cerebral infarction in 22 cases
Chinese Journal of Primary Medicine and Pharmacy 2008;15(11):1832-1833
Objective To explore the clinical effect of fleabanein in treatment of acute cerebral infarction.Methods 42 cases were randomly divided into treatment group(22 cases) and control group(20 cases).Treament group is given iv.fleabanein and compared with control group.Results The cured and effective cases of treatment group is 18 cases,that of control group is 8 cases,there is obvious difference(P < 0.05).Conclusion Fleabanein has better effect on acute cerebral infarction.
10.Fatty acid-binding proteins and the early diagnosis of cardio-cerebrovascular diseases
International Journal of Cerebrovascular Diseases 2010;18(2):128-131
Currently, the commonly used diagnostic markers have the shortcomings of lower sensitivity or specificity in the early diagnosis of cardio-cerebrovascular diseases. Therefore, it needs to use the novel specific biochemical markers for the early diagnosis arid treatment, so as to decrease the high mortality and disability caused by cardio-cerebrovascular events. Fatty acid-binding proteins (FABPs) are a family of low-molecular-weight intracellular lipid-binding proteins. They are divided into 9 different subtypes, including the liver-, intestinal-, heart-, brain-, adipocyte-, skin-, ileal-, myelin-, and testis-subtype. Their primary function is to transport long-chain fatty acids into the cells, and thus regulate intracellular lipid metabolism. The structures of all FABP subtypes are similar, inclusive of two α2 helices arid one β2 fold structure. Among them, the sensitivities and specificities of the heart- and brain-subtype FABPs are higher in the early diagnosis of cardio-cerebrovascular diseases. It is promising to become the novel markers in the early diagnosis of cardio-cerebrovascular diseases.