1.The Clinical Study of the Stereotactic Conformal Radiotherapy for Brain Stem Tumors
Journal of Medical Research 2006;0(08):-
Objective 18 patients of brain stem tumors in results were analyze retrospective by Stereotactic Conformal Radiotherapy.Methods From March 2000~March 2005.18 patients with brain stem tumors were treated by SCRT.The patients age were 6~67 years old,midian age were 28 years.The dose was 45~60Gy/5~7week.Results The symptoms had been improved in 15/18 cases at the end of the radiotherapy.The 1-3 and 5 year survival rates were 57.6%,42.6% and 30.4%.The complication occurrence rate was 13.13%.Conclusions The Stereotactic Conformal Radiotherapy is a main therapy mean to brain stem tumors.That can improved survival rates and life quality of the patients with brain stem tumors.
2.Studies on Chemical Compositions of Fatty Oil in Fructus Quisqualis by Supercritical Fluid Extraction and Gravimetric and GC - MS Analysis
China Pharmacy 1991;0(04):-
OBJECTIVE: To analyze the oil content and fatty acid constituents of Fructus Quisqualis.METHODS: The fatty oil of Fructus Quisqualis was extracted by supercritical fluid extraction (SFE) .The content of oil and compositions of fatty acid were determined by gravimetric analysis and GC - MS respectively .RESULTS:The oil content of Fructus Quisqualis was 27.70% .Among the fatty acids, oleic acid, linoleic acid and palmitic acid were dominant.The unsaturated fatty acids accounted for 63.93% of the total fatty acids, and the major saturated fatty acid was palmitic acid .CONCLUSION: The oil of Fruclus Quisqualis is of highquality,and the analytic results provide scientific basis for exploitation and utilisation of the oil of Fructus Quisqualis.
3.Therapeutic Observation of Matrix Needling for Functional Dyspepsia
Shanghai Journal of Acupuncture and Moxibustion 2015;(6):524-526
Objective To observe the clinical efficacy of acupuncture in treating functional dyspepsia. Method Sixty-eight patients with functional dyspepsia were randomized into an acupuncture group and a control group. The acupuncture group was intervened by matrix needling, once a day, 8 d as a course, with a 2-day interval between two courses, for successive 4 weeks. The control group was prescribed with Motilium at 10 mg, 3 times a day, for successive 4 weeks. Result The total effective rate was 91.4% in the acupuncture group versus 87.9% in the control group, and the difference was statistically insignificant (P>0.05); there was a significant difference in abdominal pain score between the two groups (P<0.05), indicating that the acupuncture group should be superior to the control in releasing abdominal pain. Conclusion The overall efficacies in treating functional dyspepsia are equivalent between the acupuncture group and control group, but the acupuncture group is better than the control in releasing pain. Therefore, compared to medicine, acupuncture has advantage in treating functional dyspepsia.
4.Effects of recombinant human interleukin-11 on the vaginal epithelium mitosis of estrone periodical mice and the expression of PCNA
Chinese Journal of Biochemical Pharmaceutics 2016;36(4):49-51
Objective To investigate the therapeutic effects of recombinant human interleukin-11 (rhIL-11) on the vaginal epithelium mitosis of estrone periodical mice and the exprssion of PCNA.Methods The vaginal epithelium mitosis of estrone periodical mice was used as the epidermis hyperplasia model, rhIL-11 action in regulating the epidermis hyperplasia was observed and the expression of PCNA was detected by immunohistochemistry.Results The rhIL-11 significantly inhibited the mitosis of mouse vaginal epithelium, decreased the expression of PCNA ( P <0.01).Conclusion The rhIL-11 has good efficacy in treating the epidermis hyperplasia of psoriasis by inhibiting the mitosis of epithelium and decreasing the expression of PCNA.
5.Results analysis of irregular antibodies screening and identification of the specificity
International Journal of Laboratory Medicine 2014;(21):2889-2890
Objective To discuss the distribution of irregular antibodies of red blood cells and its clinical significance .Methods Micro-column gel anti-globulin technique was used to screen and identify the irregular antibodies in 6 352 patients .Results In 6 352 patients ,there were 62 cases(27 males ,35 females)having positive results in irregular antibody detection ,and the positive rate was 0 .97% .There were 54 cases having transfusion history and/or pregnancy history ,including 43 cases of irregular antibodies of Rh system(containing 34 cases of anti-E antibody) ,7 cases of MNSS system ,2 cases of Lewis system ,2 cases of Kidd system ,2 cases of P system ,1 cases of Diego system ,and 5 cases with non-specificity .All of the patients whose irregular antibodies of Rh blood group system were positive had transfusion history and/or pregnancy history .Conclusion Most of the patients with irregular anti-body positive are females ,who mostly have transfusion history and/or pregnancy history ,and the irregular antibodies of Rh system are the most common .
6.Pathogens and drug-resistance of ventilator-associated pneumonia patients in emergency intensive care unit
Chinese Journal of Postgraduates of Medicine 2010;33(22):9-11
Objective To observe the pathogens and drug-resistance of ventilator-associated pneumonia (VAP) patients in emergency intensive care unit (EICU) for rational antibiotic therapy and the prevention of VAP. Method The sputum culture results and drug-resistance of pathogens of VAP patients in EICU from 2007 to 2009 were collected. Results One hundred and two mechanical ventilation patients were selected. VAP was occurred in 70 patients (68.6%). One hundred and fifty-seven pathogens had been examined,including 92 Gram-negative bacilli (58.6%),35 Gram-positive cocci (22.3%) and 30 fungus (19.1%). Pseudomonas aeruginosa and meticillin-resistant-staphylococcus aureus was 22 strains (14.0%)respectively, stenotrop homonas maltophilia was 21 strains (13.4%) and acinetobacter baumanii was 17 strains (10.8%). Fifty-nine patients (84.3%) had suffered from multiple pathogen infection, with 31 cases having 2 pathogens and 28 cases having 3 pathogens. Conclusions Pseudomonas aeruginosaa,methicillinresistant staphylococcus, stenotrophomonas maltophilia and acinetobacter baumanii are main pathogens of VAP in EICU patients,and candida albicans is still the main pathogens in fungal infection. The rate of multiple pathogen infection is very high, and the problem of drug-resistance is very severe.
7.Determination of the Content of Magnesium in Sodium-magnesium Fructose-1,6-d iphosphate by Ion Exchange-EDTA Titration
China Pharmacy 2001;0(08):-
OBJECTIVE:To establish a simple method of the magnesium measurement i n the sodium-magnesium fructose-1,6-diphosphate METHODS:Ion exchange-EDTA titration was adopted RESULTS:The RSDs of both the precision and accuracy wer e less than 0 51% by the method(n=6) CONCLUSION:This method is convenient ,and the results are accurate It can satisfy the determination of sodium-magn esium fructose-1,6-diphosphates
8.Clinical Thoughts on Yin-wei Theory
Journal of Zhejiang Chinese Medical University 2015;(9):662-665
Objective]To explore the relationship between Yin-wei theory and clinical practice ,and to discuss how to apply Yin-wei theory to solve practical problems in clinical situation.[Methods]We start from the Traditional Chinese Medicine(TCM) classics Nei Jing(the Canon of Internal Medicine) and Nan Jing(Canon On Eighty-One Difficult Issues),combined with Zhang Zhongjing’s application of Guizhi decoction in his book“Treatise on Febrile and Miscellaneous Diseases”to explore the cause and effect of Yin-wei theory and to comprehensively analyze its underlying thought .[Results]We found that Guizhi decoction in the“Treatise on Febrile Diseases”was not only applied in the chapter Taiyang disease,but also involved in other four chapters of Shaoyin disease and the chapter of cholera disease.In“Synopsis of Golden Chamber”,Guizhi decoction was used to treat vomitus gravidarum and affection by cold after delivery,while in Zhongjing’s practice,Guizhi decoction derived formula was widely used in the treatment of consumptive internal injuries miscellaneous disease,indicating that many internal injuries miscellaneous diseases were closely related to external infection .Tonic medicines were rarely seen alone in classical consumptive disease treatment.[Conclusion]Practice has proven that deep learning and understanding of Yin-wei theory has great guiding significance for us to put knowledge in TCM classic theories into clinical practice .Yin-wei theory opens an important window to learn“Treatise on Febrile and Miscellaneous Diseases”and trains clinical thinking,which is worth further discussion.
9.Educational practice of medical students' harmonious dormitory interpersonal relationship
Chinese Journal of Medical Education Research 2017;16(8):838-842
[Alstract] The harmonious dormitory interpersonal relationship of medical students will be of great significance to the development of college students' physical and mental,academic and construction of harmonious campus,medical environment.At present,there are four characteristics of building a harmonious medical students' dormitory interpersonal relationship:the atmosphere of dormitory culture construction is not strong,management and intervention system is not sound,the bodies of interpersonal relationship education are insufficient,and the degree of recognition is lower.The paper puts forward building the education model of one core,two wings,three combinations,the three culture as the core,university quality education and college vocational education as the two wings,combining themselves,parents,school,to provide a theoretical basis and practice guidance to establish a harmonious dormitory interpersonal relationship.
10.Core knowledge and skill-based approach to subspecialty construction in critical/intensive care medicine with distinct Chinese peculiarity
Chinese Critical Care Medicine 2017;29(6):556-559
With the rapid development of critical care medicine (CCM) in China, there are increases in the number of intensive care units (ICUs), the scale of one center ICU and the team. Subspecialty construction of CCM is of great concerns for personnel training as well as discipline development, and is currently one of the urgent problems that need to be resolved. Experience of CCM subspecialty construction from Europe and the United States is lacking and it is necessary to propose some opinions on innovation to construct CCM subspecialties with Chinese characteristics. We believe that CCM sub-specialties construction should be based on the core knowledge (pathophysiology) and skill (organ monitoring and support). The following 7 sub-specialties can be set up: ① acute lung injury and mechanical ventilation; ② shock, hemodynamic monitoring and treatment; ③ acute kidney injury and blood purification; ④ sepsis and anti-infective therapy; ⑤ stress, sedation and analgesia; ⑥ nutrition and metabolic support; ⑦ coagulation, immune and inflammation. The core knowledge and skills of critical care medicine will constantly be updated and enriched. Therefore, sub-specialty settings should be constantly updated as well.