This paper reviews some problems from five aspects such as being good at querying to enlighten students to think on their own,giving examples skillfully to arouse study interesting,summarizing timely to improve study efficiency,linking with clinic to cultivate the practice capability and using multimedia reasonably.

Objective To observe the clinicai effect of treating intestinal inflation after gynecogenic operation with aeupoint iniection.Methods 52 patients with intestinal inflation after gynecogenic operation were randomly divided into a treatment group and a control group.The treatment group was treated with point injection of neostigmine on bilateral Zusanli,and the control group was treated with neostigmine by intramuscular injection.The therapeutic effects were observed in both the treatment group and the control group.Results The therapeutic effect in the treatment group was significantly better than the control group.with P＜0.05.Conclusion The treatment of point injection of neostigmine on bilateral Zusanli has better effect in treating intestinal inflation after gynecogenic operation than injecting neostigmine by intramuscular.

Objective To ohserve clinical effect of adjuvant therapy of children bronchial pneumonia with complex pulse magnetic therapeutie apparatus.Methods 65 cases with children bronchial pneumonia were randomly divided into a control group and a treatment group.Routine treatment was performed in the control group,while the treatment group was treated with complex pulse magnetic therapeutic apparatus plus routine treatmenL Compare the clinical effect and adverse reaction between the two groups.Results Clinical effect of the treatment group was obviously higher than that of the control group,showing a significant different(P＜0.05).Moreover,no adverse reaction occurred in the treatment group.Conclusion Adjuvant therapy of children bronchial pneumonia with complex pulse magnetic therapeutic apparatus demonstrated a better effect than routine treatment.It's worthy to promote application of this therapeutic method clinically.

Objective To explore the clinical features and treatment of polycythemia vera(PV)complicating stroke.Methods Clinical data of 27 cases of PV complicating stroke were analysed retrospectively.Results(1)Among all the cases,PV complicating cerebral infarction were 22 cases(81.5%),among the 22 cases,18 cases(66.7%)of multiple cerebral infarction,2 cases(7.4%)of transient ischemic attack,2 cases(7.4%)of cerebral hemorrhage,1 case(3.7%)of subarachnoid hemorrhage(SAH).The patients's clinical manifestation,physical sign,hemogram,marrow characteristic were consistent with that of PV diagnosis criteria.(2)Imageology check show that small infarction focus were common(66.7%).Lobe of brain,basal ganglia,capsula interna were common place of cerebral infarction.The density of hemorrhagic focus was asymmetrical,there was obvious edema around the hemorrhagic focus.(3)Applied vein blood-letting and small dose chemotherapy,8 cases were recovery,18 cases were obviously improved,1 case of stroke was invalid.Conclusion The cerebral infarction are common in PV complicating stroke.Among all the PV complicating stroke cases,multiple cerebral infarction are the most common,cerebral hemorrhage and subarachnoid hemorrhage are few,vein blood-letting and small dose chemotherapy has a good curative effect for the patients.

Objective To observe the protective effect of goserelin on ovarian function of premenopausal patients with breast cancer during chemotherapy. Methods Forty patients with breast cancer under 40 received adjuvant chemotherapy were randomly divided intotest group(20 cases) and control group (20 cases). Compared the recovery rate and time of menstruation between two groups. Results All the 40 patients finished the treatment. Recovery ratio of normal ovarian function in test group and control group was 75% and 50% (P =0.013) respectively, and the median menstrual recovery time in two groups was 4.65 months and 6.65 months (P = 0.046) respectively. Statistically significant differences were found between two groups. Conclusion Goserelin can effectively protect ovarian function during chemotherapy , increase the ratio of normal ovarian function, shorten menstrual recovery time, and shows good tolerance.

Objective To explore the selection of reasonable interventional treatment to portal hypertension under different conditions.Methods The data of 76 patients with portal hypertension and interventional treatment from 1997 to 2002 were retrospectively analyzed. 26 patients were treated with transjugular intrahepatic porto-systemic stent shunt (TIPSS). Of these 26 patients, 11 patients suffered from hemorrhage after surgery treatment by devascularization, 6 patients with hemorrhage after stomach mirror treatment, and 9 patients with ineffective medicine treatment. 50 patients were treated with percutaneous transhepatic variceal embolization (PTVE) combined with partial splenic embolization (PSE), and they all showed inefficacy by medicine treatment. Free portal pressure (FPP) in pre- and post-treatment was measured in all 76 cases. The hepatic volume was measured by spiral-CT before and one year after the treatment.Results In TIPSS group, FPP was reduced from (3.85?0.42) kPa to (3.09?0.44) kPa (( t= 3.682, P

Objective To evaluate the clinical feasibility and validity of interventional therapy in thrombo angitis obliterans. Methods 13 patients with thrombo angitis obliterans were treated with percutaneous left subclavian artery port catheter system implantation. The catheter external iliac artery with perfusion of prostaglandin E1 (PGE1) 100Ug, urokinase (UK) 200,000U and mailuoning 20 ml every day. Each treatment lasted for 7 10 days. Results 13 patients with angiographic demonstration showed occlusions of 1 case in the middle segment of superficial femoral artery, 9 cases of complete occlusion in popliteal artery and same for 3 cases in anterior tibial artery, the end of the peroneal artery and posterior tibial artery. After treatment, 3 patients had to undergo amputation due to gangrene in foot and 10 patients with no gangrene showed skin temperature rising up in the lower limb. Intermittent claudication and rest pain were relieved obviously accompanied by increasing step distance over 500 m with the Fontain grade improvement of twice at least. Follow up angiography one year later showed large quantity of vasculogenesis in the lower limb. Conclusion The treatment of trans port catheter system is excellent and practical for improving the clinical status of patients with thrombo angitis obliterans.

Objective To evaluate the X-ray characterstics of benign and malignant neoplasms on mammography in order to improve their differeatial diagnostic level.Methods X-ray image changes of 67 malignant breast neoplasms were described by the mammography and in comparision with those of 31 benign masses .Results The accordance percentages between the X-ray and histological examinations for the malignant and benigin neoplasms were shown to be 89.6% and 84.0% respectively. Occurrence of masses with an enhanced density , irregular shape, calcification granules in clusters were found to be indication of a malignent lesion.Conclusion The mamography can provide effective imaging data for differential diagnosis betweren the benign and malignant breast neoplasms.

This paper introduces the comparative approach including its implication,implementing ways and values in efferent nervous pharmacological teaching from characteristics of efferent nervous pharmacology.It can be concluded that comparative approach is the suitable teaching method in the teaching of efferent nervous pharmacology.

Objective To evaluated the role of wt-P53 protein in telomerase regulation in keloid fibroblasts(KFBs). Methods The fibroblasts were derived from human keloid tissue which was proved by pathological diagnosis. KFBs were divided into 2 groups, the transfection group and the untransfection group. wt-p53 gene was transfected into the fibroblasts by adenovirus vectors in the transfection group. The KFBs untransfected with wt-p53 gene served as control (untransfection group). After 48 hours of transfection, the expression of wt-P53 protein was analyzed by both Western blotting and immunofluorescence method, respectively. The telomerase activity was evaluated by TRAP-ELISA after 1-7 days of transfection.Results All the KFBs from 2 groups expressed wt-P53 protein. But the expression level of wt-P53 protein in the transfection group was significantly higher than that in the untransfection group. At the same time of high expression of wt-P53 protein, the telomerase activity of KFBs in transfection group was significantly lower than that in the untransfection group( P＜0.05). Conclusion High level expression of wt-P53 protein can transiently inhibit the telomerase activity of KFBs.