1.Improving the integrated ability of English by news reading and broadcasting
Chinese Journal of Medical Education Research 2014;13(12):1272-1275
Objective Through the English newspaper reading activities to create the information transmission platform based on the medium of English,so as to improve the students' ability of receiving,understanding,conversion,processing,and output information.Methods Two natural classes of seven-year program students of Grade 2011 with no difference in Englishproficiencywere selected at randomas control group(30) and the experimental group(30).And reform on reading course has been performed in the experimental class by incorporating English newspaper reading into traditional teaching routine,while the control class maintain the traditional teaching routine.After the teaching,through CET 4 test scores to evaluate the teaching effect.Independent t-test was conducted on the performances of CET 4 between the experimental class and controlled class with the level of test α=0.05.Results The control group was higher than the experimental group inthe total scoreof CET 4 and the performance oflistening and reading,and there was significant difference between the two groups(P of totalscore=0.000,P of listening score=0.002,P of reading score=0.001).But there was no statistically significant difference in writing subtests between the two groups(P=0.072).Conclusion By adopting English newspaper reading and broadcasting in class,students' overall ability of using English has been greatly enhanced,especially the listening comprehension and reading comprehension; however,there is no significant change in the development of students' writing ability due to the tasks designed.
2.Diagnosis and treatment of vasovagal syncope in children
Chinese Pediatric Emergency Medicine 2010;17(6):488-491
Eighty percent of unexplained syncope children can be diagnosed of vasovagal syncope (VVS). Positive head-up tilt test (HUTT) leads to the diagnosis of VVS. However,organical diseases which can cause syncope should be excluded before HUTT was taken. The therapies of VVS include nonpharmacological therapy (health education, head-up training, water and salt supplement), pharmacological therapy (β-blockers, α-receptor agonists, fludrocortisone, selective serotonin reuptake inhibitors, angiotension converting enzyme inhibitors, et al.) and pace maker.
3.Detection of Insoluble Particles in Compound Kushen Injection Mixed with 4 Infusion Solution
Baofeng YANG ; Yuhua WANG ; Lijia FU
China Pharmacy 2005;0(24):-
OBJECTIVE:To investigate the infusion solutions which are compatible with Compound kushen injection. METHODS:The insoluble particles of kushen injection in four kinds of infusion solutions were detected respectively by light blockage method.RESULTS:Insoluble particles of different size and number were noted for Compound kushen injection when mixed respectively with four kinds of infusion solutions,but the insoluble particles in all kinds of infusion solutions except 10% glucose injection were all within the range specified in China Pharmacopeia(2005 edition).CONCLUSION: 0.9% sodium ch-loride injection is the optimal compatible infusion solution for Compound kushen injection.
4.Cell growth factors for repair of skeletal muscle injury
Dapeng WANG ; Guimei ZHANG ; Lijia LUO
Chinese Journal of Tissue Engineering Research 2016;(2):273-278
BACKGROUND:A variety of cel growth factors are involved in skeletal muscle regeneration; moreover, these factors cooperate with each other to promote muscle repair and regeneration. OBJECTIVE:To explore the synergy mechanism of a variety of cel growth factors in promoting damage repair. METHODS:By using literature survey, Wanfang, CNKI and PubMed databases were searched for articles related to exercise-induced muscle damage and repair using the keywords of “cel growth factor; skeletal muscle damage;repair; fibroblast growth factor” in Chinese and English, respectively. Research achievements related to exercise-induced muscle damage, molecular biological characteristics of cel growth factors and skeletal muscle injury repair are discussed. RESULTS AND CONCLUSION: Basic fibroblast growth factor plays a basic biological role to promote cel proliferation and angiogenesis, which is the strongest cytokine known to promote cel growth and reflects a very important role in skeletal muscle repair. Epidermal growth factor is synthesized by monocytes and ectodermal cels, which is prominent to stimulate the division and proliferation of a variety of tissues and cels, enhance cel movement, division and synthesis of interstitial protein. Insulin-like growth factors are a family of insulin-like growth factor 1-related and insulin-like growth factor 2-related peptides, which can promote muscle protein synthesis, promote muscle cel proliferation and differentiation, and participate in skeletal muscle regeneration and repair, thereby accelerating wound healing of the muscles. Neurotrophic factor is a kind of trace soluble substances around sensory neurons and produced by neuron-targeted cels, which can specificaly promote neuronal growth and maintenance, and promote skeletal muscle repair. But studies on the synergy mechanism of a variety of cel growth factors in the repair of exercise-induced muscle damage are just at the initial stage, and further research is necessary.
5.Volume control of peritoneal dialysis in elderly patients
Lijia ZHAO ; Fenghe DU ; Tao WANG
Chinese Journal of Geriatrics 2003;0(12):-
Objective Cardiovascular mortality and morbidity is common in dialysis patients and fluid overload is the most important contributor. The aim of this study was to investigate the relationship between volume overload and hypertension in elderly continuous ambulatory peritoneal dialysis (CAPD) patients and effect of dietary salt restriction on blood pressure control. Methods Thirty-eight CAPD patients with age of 60 years old and over were enrolled in the present study. 38 patients with CAPD were restricted the intake of salt and fluid in stable CAPD patients for two months. Their body weight, extracellular water (ECW), intracellular water (ICW), total body water (TBW), blood pressure, serum albumin levels, urine volume and ultrafiltrate volume were measured before and after the dietary restriction. Bioimpedance analysis was used to assess their fluid status. ECW was normalized by patients' ideal weight (nECW). Results After dietary salt restriction, significant deceases in body weight 〔(60.5?10.3) kg vs (58.5?9.7) kg, P =0.000〕, ECW 〔(15.81?3.03) L vs (14.65?2.61) L, P =0.000〕 and systolic blood pressure 〔(134.0?18.3) mm Hg vs (128.3?21.0) mm Hg, P =0.05〕 were observed in 26 patients whereas the opposite changes were observed in the remaining 12 patients. A significant correlation was found between systolic blood pressure and nECW both before and after two months of dietary restriction ( r _ pre =0.379, P =0.019; r _ post =0.393, P =0.016) and between the changes in systolic blood pressure and changes in nECW ( r =0.514, P =0.001). Conclusions The present study suggests that there is a positive correlation between fluid status and blood pressure. Most of the elderly CAPD patients are fluid overloaded and that dietary salt restriction may be an effective way to control volume and blood pressure. However, the compliance of patients to dietary salt restriction can influence the effect.
6.The Research of Serum IgG Subgroup in Clild Patients with Juvenile Rheumatoid Arthridylitis
feng, XIONG ; leili, DENG ; lijia, WANG ; xiqiang, YANG
Journal of Applied Clinical Pediatrics 1992;0(05):-
0.5).IgG、IgA and IgM of controlgroup and observation group in 10~13 years old are similar to that in 5~9 years old group. The IgG_1of control group and observation group in 5~9 years old are 5.501?0.976 and 9.715?3.746g/L respe-etively (t=5.046, P0.05),IgG_3 are0.517?0.167 and 0.828?0.578g/L respectively (t=2.132, P0.05).The IgG_2 Levels of observation groupis higher than that of control group in 10~13 years old(P
7.Renoprotective effect of simvastatin on adriamycin-induced nephropathy in rats
Wei ZHANG ; Qiu LI ; Lijia WANG ; Xiqiang YANG
Journal of Third Military Medical University 2003;0(22):-
Objective To investigate the role of interleukin-1 beta (IL-1?) in glomerulosclerosis secondary to adriamycin (ADR)-induced nephropathy in rats, and the effect of simvastatin on the expression of IL-1?. Methods Male Sprague-Dawley rats were randomly divided into normal control, ADR-induced nephropathy (model), and simvastatin-treated ADR nephropathy (treatment) groups. After ADR-induced nephropathy establishment in model and treatment groups, and eleven weeks of intragastrical administer of normal saline in normal control and model groups and of simvastatin in treatment group, the expression of IL-1? was detected by immunohistochemistry, RT-PCR and ELISA. Histopathological change of renal tissues was observed under light microscope, and glomerulosclerosis index (GSI) was also evaluated. Results Higher expression of IL-1? in kidney and GSI, as well as more severe loss of renal function were observed in model group than those in control group (all P
9.Infection of respiratory syncytial virus in BALB/c mice and nude mice
Juan ZHOU ; Xiqiang YANG ; Xiaodong ZHAO ; Lijia WANG ; Liping JIANG
Chinese Journal of Microbiology and Immunology 2008;28(10):909-913
Objective To compare respiratory syncytial virus(RSV)infection and inflammatory responses between immunocompetent BALB/c mice and immanodeficient nude mice.Methods At various time points after BSV infection of BALB/c mice and nude mice,pulmonary viral titers were assayed.Leukocvtes in bronchoalveolar lavage fluid(BALF)and pulmonary histology were identified.F4/80+cells and CD49b+cells in lung tissue were examined by immunohistochemistry,and the cytokines of TNF-α,IL-12,IFN-r and IL-10 in BALF were assayed by ELISA.Results RSV titers in infected BALB/c mice and nude mice peaked on the 3rd day postinoculation,and nude mice had higher-level and more durative viral replication than BALB/c mice.RSV infection induced more severe pulmonary histopathology and larger number of leukocytes in airway in nude mice than in BALB/c mice.RSV infection enhanced more pulmonary F4/80+macrophages,CD49b+ NK cells in both mice.Furthermore infected nude mice had larger amount of pulmonary macrophages and NK cells than infected BALB/c mice.RSV infected BALB/c mice secreted more TNF-α,IL-12,IFN-r and IL-10 as compared with control BALB/c mice,and infected nude mice had hisher level of TNF-α.IL-12 and IL-10 than infected BALB/c mice.Conclusion Nude mice are good model for severe and pemistent RSV infection in immunocomprised hosts.The inflammation induced by RSV infection is not parallel with the immune response of T cells,and macrophages and NK cells are potent immunocytes and inflammatory cells in RSV infection especially when T lymphocytes are absent.
10.Research Progress on Role of Hepatic Stellate Cells in Liver Development and Regeneration
Lijia YAO ; Xing DENG ; Wei WANG ; Weifen XIE
Chinese Journal of Gastroenterology 2016;21(3):183-186
Hepatic stellate cells(HSCs),the pluripotent cells,exist between liver sinusoidal endothelial cells and hepatic epithelial cells. Activated HSCs transform to myofibroblast-like cells,start to proliferate,and de novo express some proinflammatory and profibrogenic genes,which promote hepatic fibrogenesis. Previous studies mainly focused on the relationship between HSCs and liver fibrosis,however,recent studies indicate that HSCs are essential for proliferation, differentiation and maturation of various liver cells in the process of liver development and regeneration. This review systematically summarized the source,developmental regulation and function of HSCs,and focused on progress of recent studies on the role of HSCs in liver development and regeneration. The novel knowledge of HSCs may provide clues for treatment of liver diseases.