Objective To compare the clinical efficacies of transverse insertion of a thick needle into point Shendao(GV11) versus conventional acupuncture in treating facial neuritis of different durations.Method Two hundred and twenty patients meeting the inclusion criteria were randomly allocated to thick needle and tradition groups. The two groups separately received corresponding treatment in addition to oral administration of Western medicine. The therapeutic effects were evaluated using the House-Brackmann rating scale and the Portmann's Simple Scale (RPA) for facial symptoms and compared after two courses of treatment.Result The therapeutic effect was better, posttreatment H-B rating scale score was lower and posttreatment RPA score was higher in the thick needle group than in the tradition group; there were statistically significant differences (P<0.05). Different durations of disease affected the therapeutic effect. In the thick needle group, the therapeutic effect was better in the patients in the early stage than in the middle and late stages; there was a statistically significant difference (P<0.05). The cure rate was higher in the patients in the early and middle stages in the thick needle group than in the tradition group; there was a statistically significant difference (P<0.05). Conclusion Transverse insertion of a thick needle into point Shendao has a definite therapeutic effect on facial neuritis. It is safe, easily performed and of an advantage over conventional acupuncture.

OBJECTIVE:To provide references for the establishment and evolvement of national drugs policy as well as its related research.METHODS:The contents of the new drug strategy and the contents subjected to regular monitoring and evaluation as well the cooperative implementation of the strategy etc were introduced,and its implication for China was analyzed.RESULTS & CONCLUSIONS:The accessibility to essential drugs can be guaranteed with the help of WHO's new drugs strategy,likewise,the accessibility to essential drugs in China can't be realized without the great support of the national drugs policy and the sustainable efforts of both the government and the society.

Objective To evaluate the clinical significance of laparoscopic resection for large intramural hysteromyoma. Methods A retrospective analysis was made concerning 42 cases of single intramural hysteromyoma as large as 6～10 cm in diameter: 24 cases underwent laparoscopic hysteromyomectomy and 18 cases received open resection. Intra- and post-operative parameters between the two groups were compared. Results All operations in the two groups were successfully completed without complications. The operative time was significantly longer in the laparoscopic group (89.0?26.9 min) than that in the open group (63.3?20.1 min) ( t=3.400,P =0.002). No statistical difference was observed in the intraoperative blood loss between the laparoscopic group (93.6?65.9 ml) and the open group (100.0?48.7 ml) ( t=-0.347, P=0.731) . The analgesic requirement was less in the laparoscopic group (2 out of 24 cases ) than that in the open group (9 out of 18 cases) ( ? 2 =7.208, P =0.007). The time to first flatus was shorter in the laparoscopic group (23.5?11.3 h) than that in the open group (32.0?13.6 h) ( t=-2.211, P =0.033). The postoperative pyrexia rate was significantly lower in the laparoscopic group (2/24) than that in the open group (7/18) ( ? 2=4.033, P =0.045). Conclusions Laparoscopic resection for larger intramural hysteromyoma is safe and reliable. As compared with open hysteromyomectomy, it offers more rapid recovery and lower postoperative pyrexia rate, as well as the same amount of blood loss. Its prolonged operative time may be associated with the relatively large size of the hysteromyoma.

[Objective] To observe the effect of different acupoint application therapies :a summer treatment for the winter disease on allergic rhinitis ,and compare the relationship between the different acupoints and therapeutic effect. [Methods ] The 81 cases of allergic rhinitis who met inclusion criteria were divided into 12 acupoint group and 6 acupoint group. The time of application was in first ten-day period of the hot season. The duration of application was 2h. The days later, namely in the second ten-day period of the hot season, and twenty days later, in the third ten-day period of the hot season, the application was repeated respectively. Before treatment and half year after the treatment, the score of quality of life, symptoms of allergic rhinitis were observed to compare the relationship between the different acupoints and therapeutic effect. [Results] The effective rate was higher in 12 acupoints group than 6 acupoints group. After treatment, the score of quality of life, symptoms of allergic rhinitis were significantly improved( P<0.05 or P<0.01). And the comparison of the therapeutic effect of two groups showed significant difference in statistics( P<0.01). [Conclusion] The acupoint application therapy is effective for allergic rhinitis, and the comprehensive combination of acupoint is influential on the effect.

Objective To investigate the effect of Problem- based Learning (PBL) applied in the course of Activities of Daily Living (ADL) Skills and Environmental Adaptations. Methods PBL (PBL class) and traditional teaching (traditional class) were applied in different classes. Their scores of the final examination were compared, and the students were investigated with the questionnaire. Results The scores of final examination were higher in the PBL class than that in the traditional class (P<0.05). Most of the students accepted the PBL in the course. Conclusion PBL can improve the quality of teaching of occupational therapy.

Objective To investigate the efficacy of transverse insertion of thick needles into the Du meridian in treating rat ischemic facial paralysis and preliminarily explore the possible mechanism by which it produces a therapeutic effect. Methods Sixty Wistar rats were randomly allocated to groups A (transverse insertion of thick needles), B (basic Western drugs), C (blank control) and D (sham operation), 15 rats each. A rat model of ischemic facial paralysis was made using a modified vascular occlusion method in all the rats. Facial nerve deficits were scored in every group of rats during treatment. At 1 day after model making, group A was treated by transverse insertion into point Shendao and 4-hour retention of needle, once daily, for a total of 14 days; group B was treated by an oral gavage of prednisone and intraperitoneal injection of vitamine B12, once daily, for a total of 14 days. Groups C and D were not treated. In 4 rats randomly chosen at 3, 7 or 14 days after model making, facial nerve concomitant intrinsic vascular tissue HIF-1αprotein was measured by an immunohistochemical method; serum NO, by enzyme-linked immunosorbent assay; serum ET content, by radioimmunoassay.Results After 7 days of treatment, the neurological deficit score increased gradually in groups A and B and there was a statistically significant difference compared with after model making in the two groups (P<0.01). After 7 days of treatment, there was a statistically significant difference in the neurological deficit score in groups A and B compared with groups C and D (P<0.05) and between groups C and D (P<0.05). After 14 days of treatment, there was a statistically significant difference in the neurological deficit score between group A or B and group C (P<0.05) and between group B or C and group D (P<0.05). In group A, there was a statistically significant difference in the neurological deficit score after 14 days of treatment compared with after 7 days of treatment (P<0.05). After 3, 7 and 14 days of treatment, there was a statistically significant difference in HIF-1αMOD value in groups A , B and C compared with group D (P<0.01). After 3 and 7 days of treatment, there was a statistically significant difference in HIF-1αMOD value between group A or B and group C (P<0.05). In groups A and B, there was a statistically significant difference in HIF-1αMOD value after 3 and 14 days of treatment compared with after 7 days of treatment (P<0.05). After 3 and 7 days of treatment, there was a statistically significant difference in serum NO content between group A or B and group D (P<0.01). In groups A and B, there was a statistically significant difference in serum NO content after 7 days of treatment compared with after 3 days of treatment (P<0.05). After 3 and 7 days of treatment, there was a statistically significant difference in serum ET content in groups A , B and C compared with group D (P<0.05). In groups A and B, there was a statistically significant difference in serum ET content after 7 days of treatment compared with after 3 days of treatment (P<0.05).Conclusions Transverse insertion of thick needles into the Du meridian can effectively promote rat’s recovery from ischemic facial paralysis. The mechanism by which it produces a therapeutic effect may be regulating the expression of tissue HIF-1α and the NO and ET contents of serum.

Objective: To study relationship between exercise and risk factors for cardiovascular diseases. Methods: A total of 750 military cadres retired or on the job, who received convalescence therapy in Guangzhou sanatorium, were enrolled as survey subjects, and divided into exercise group（488 cases）, and no- exercise group （262 cases）. The cardiovascular risk factors such as blood pressure, body mass index (BMI), fasting blood glucose（FBS）, total cholesterol （TC）, triglyceride （TG）and uric acid were measured. Questionnaires were used to survey mode of exercise, exercise frequency, exercise duration each time and total exercise time in a day. Results: 1. In no-exercise group, levels of systolic blood pressure, diastolic blood pressure, BMI, FBS, TC and TG were significantly higher than those of exercise group (P<0.05 all), but there were no significant difference in age and levels of HDL-C, LDL-C and uric acid between the two groups（P＞0.05 all）; 2. （1） Abnormal rate of risk factors for cardiovascular diseases （call for short was risk rate, similarly hereinafter）in different exercise duration each time （≥30 min、＜30 min）and exercise mode（walking, taijiquan）were no significant（P＞0.05 all）;（2）Risk rate in subjects who took exercise >60min in a day was significantly lower than that of those with ≤60min (29.41% vs. 45.59%), in subjects whose exercise intensity with RPE（Borg rating of perceived exertion scale）11~15 was significantly lower than that of with RPE <11 (33.67% vs. 44.64%), P<0.05 all;（3）Risk rate in subjects whose exercise frequency ≥3 times/week was significantly lower than that of with ＜3 times/week （31.47% vs.8.43%）, in subjects whose persistence time of exercise was 10～19 years was significantly lower than that of with ＜10 years, P<0.05 all. Conclusion: 1. Risk extent of cardiovascular diseases is lower in exercise group, and there is additive effect in risk factor for cardiovascular diseases; 2. take exercise >60min/d, Borg rating of perceived exertion scale 11~15, exercise frequency ≥3 times/week and long time persistence are conduce to decrease risk of cardiovascular diseases in middle-aged and aged persons.

0.05).The successful rates of weaning from MV of embedment group(60%,75%) were significantly higher than those of control group(30%,35%) and traditional needle group(25%,30%) in the 2 nd and 4 th week after treatment(all P

Objecve To observe the clinical effect and safety of the Chinese medicine syndrome differentiation combined with HAART for the ADC(acquried immune deficiency syndrom dementia complex). Methods A total of 80 patients with ADC were divided into the treatment group and control group based on random number table, 40 in each group. The patients in the control group were treated by highly active anti-retrovital therapy (HAART). The patients in the treatment group were treated with TCM treatment on the based of the control group. Both groups received the treatment for 3 months.These outcomes were measured: TCM syndrome integral, mini mental state examination(MMSE), daily behavior scale(ADL), change of clinical stage, and adverse reactions. Results The effect rate of treatment group was 82.5%, which was significant higher than 65% of the control group (χ2=8.115,P=0.024). After the treatment, the ADL integral of the treatment group (37.69 ± 5.31vs.33.67 ± 5.16;t=2.528,P=0.021) was significantly higher than that before the treatment; and the ADL integral of the control group(36.96 ± 5.52vs.34.54 ± 4.98;t=2.747,P=0.027) was significantly higher than that before the treatment.But there was no significant difference between the two groups after the treatment (t=2.003,P=0.139). After the treatment, the MMSE integral of the treatment group (24.76 ± 4.43 vs.19.97 ± 5.46;t=1.006,P=0.013) was significantly higher than that before the treatment; the MMSE integral of the control group(24.65 ± 4.36 vs. 20.11 ± 4.87;t=1.035,P=0.014) was significantly higher than that before the treatment. But there was no significant difference between the two groups after the treatment (t=0.953, P=0.347).There was no significant difference between the two groups in the clinical stage change (phase1χ2=1.231,P=0.954; phase2χ2=2.726,P=1.053). There was no adverse reaction in the two groups during the treatment.Conclusions The Traditional Chinese medcine combined with HAART was better than HAART alonein the treatment of ADC.

Objective To assess the clinical diagnostic value of sputum fungal culture combined with serum galactomannan (GM) antigen detection in patients with invasive pulmonary aspergillosis (IPA). Methods A total of 567 cases, because of respiratory symptoms and/or suspected aspergillosis infection, admitted into the Affiliated Hospital of Jining Medical University from January to December 2016 were enrolled, the positive rate of pulmonary aspergillosis infection was determined by sputum culture and serum GM test, the values of single sputum culture and the combination of the culture and GM test for diagnosis of IPA were analyzed, and the differences in the positive rates of pulmonary aspergillus determined by GM test and traditional methods [chest computed tomography (CT), sputum culture and blood culture] were compared. At the same time, when fever patients had treated for 3-4 days, the results were ineffective, antifungal therapy was applied according to the disease condition and the results of auxiliary examinations (chest CT, sputum culture and GM test), and the effect of antifungal therapy was observed. Results The serum GM test was positive in 85 cases, and sputum fungal culture was positive in 226 cases, there were 108 cases presenting positive and 148 cases negative in both culture and GM test; the diagnosis of IFD was confirmed in 186 cases (32.8%), clinical diagnosis was made in 107 (18.9%) cases, suspected in 131 (23.1%) cases and excluded in 143 cases (25.2%). Compared with single sputum fungal culture, the sensitivity [98.2% (108/110) vs. 20.4% (46/226)], specificity [85.1% (148/174) vs. 45.1% (148/328)], positive predictive value [80.6% (108/134) vs. 37.1% (46/124)] and negative predictive value [98.1% (148/151) vs. 63.0% (148/235)] of combination method of GM test and sputum fungal culture for diagnosis of IPA were obviously higher; the positive rate of GM test for the detection of pulmonary aspergillus infection was significantly higher than that of traditional methods of chest CT, sputum culture and blood culture [64.7% (55/85) vs. 35.7% (35/98), 20.4% (46/226), 4.8% (14/292)], and the GM value being 0.5 as the positive critical value for the diagnosis of IPA can provide desirable sensitivity and specificity. In this study, 186 patients with pulmonary aspergillus infection had completed the antifungal treatment. The effective rates of antifungal treatment 1, 2, 3 and 6 months after treatment were not significantly changed with the prolongation of the therapeutic time [75.4% (135/179), 77.1% (111/144), 77.2% (31/79), 82.6% (19/23)], but the contents of serum GM was significantly lowered compared with that before treatment [absorbance (A) value: 0.49±0.03, 0.46±0.03, 0.39±0.03, 0.23±0.03 vs. 0.56±0.03, all P < 0.05], the number of positive cases was also decreased (186, 179, 144, 79, 23 respectively), so dynamic GM tests can help observe the therapeutic effect. Conclusion The study results showed: serum GM antigen detection combined with sputum fungal culture can significantly improve the clinical diagnostic efficiency for patients with pulmonary aspergillus infection.