In TCM treatment of hepatitis B,one of refractory diseases,must follow strictly the principles of learning the past, but not rigidly adhere to it,and opening up and innovation. The principles of anti-virus, playing attention to objective detection. clinically re-researching, unifying disease differentiation and syndrome differentiation, as well as attaching importance to medicine toxicity and carefully selecting medicines and so on mentioned in this paper are a preliminary opinion based on the above view point in combination with long-term clinical practice and thinking.

OBJECTIVE:To provide reference for the clinical rational drug use. METHODS:Cross-sectional survey was adopt-ed to statistically analyze the off-label use of inpatient(489 prescriptions)and outpatient prescriptions(466 prescriptions)in our hos-pital in Jun. 19,2014. RESULTS:The prescription items and ratios of off-label use in inpatients and outpatients in our hospital were 240,14.1%(240/1 704)and 149,17.4%(149/852),respectively. The top 4 types of drug off-label use included changing ad-ministration frequency,indications,compatibility concentrations of injections and dosage. CONCLUSIONS:Some of off-label use are rational,supporting by kinds of guidelines,expert consensus and literature reporting;while some are irrational,clinic should avoid this kind of irrational use and be strictly controlled by pharmacists. Meanwhile,it is suggested that the drug manufacturers up-date the instructions timely to provide reference for ensuring safety drug use of patients.

Objective: To discuss the clinical features,diagnosis,pathogenesis and treatment of antiepileptic drug hypersensitivity syndrome(AHS).Methods: A retrospective analysis of one case of AHS was focused on his clinical data.Results: About six weeks after carbamazepine treatment the patient presented fever firstly.The highest temperature is up to 39.6℃.Subsequently he developed diffusible red maculopapular rash and swollen superficial lymph nodes.Physical examination found internal organs involvement(mainly liver and lung).Laboratory examinations showed that the leucocyte increased to 54.21?109/L,and the percentage and absolute count of eosinophil rose,while IgG and IgM decreased.The CT of thoracic part showed the lymph nodes of hilum of lung and mediastina swelled together with pleural effusion.A biopsy study of lymph node suggested the reactive hyperplasia which was not equal to lymphoma.The bone marrow smear showed granulocytic cell line hyperplasia and abnormal lymphocyte were observed.After discontinuing carbamazepine in time and applying corticosteroids,the temperature descended rapidly and the swollen lymph nodes recovered soon.Conclusion: AHS is an idiosyncratic reaction.It usually occurs within 2 to 8 weeks after initiation of antiepileptic drug therapy,and typically manifests itself as fever,eruption and internal organ involvements.Pathogenesis is still not definite.Important basis for diagnosis and differential diagnosis depends on clinical manifestations and laboratory examinations.Early recognition of AHS and timely discontinuing of the suspected drugs are the essential therapy.

Objective: This study is explore the risk factors of premature ovarian failure extensively providing valuable information for prevention strategies.Methods: The 1∶2 matched case-control study was conducted.Results: The single-factor conditional logistic regression analysis indicated that marriage condition,the times of induced abortion and another 12 factors were related to POF.Multivariate conditional logistic regression model indicated that marriage condition,the times of induced abortion,smoking,hair dyeing,mood,the influence of eating vegetable,and mumps were relates to POF.Conclusion: Marriage condition,the times of induced abortion,influence of eating vegetable,hair dyeing,mood and mumps were play an important role in the onset of POF.

The interaction of Klebsiella mytoca NG13/pMC73A with Eucalyptus were studied. The results showed that the root surface and even the inner cortex of Eucalyptus were colonized by K. oxytoca. The K. oxytoca was reisolated from rhizosphere, root surface and inner root of inoculated Eucalyptus. The inoculation with K. oxytoca stimulated the excretion of Eucalyptus root and affected the contents of amino acids, carbohydrates, phytohormones of root exudates. The seedlings of Eucalyptusto to inoculation with K. oxytoca increased growth, total dry matter and N content by 29.81% - 100.40% after 3 months in comparinson to the uninoculated seedlings.

Objective:To investigate the risk of heparin leading to upper gastrointestinal bleeding in elderly patients undergoing percutaneous coronary intervention(PCI).Methods:To compare characteristics of unfractionated heparin and low molecular weight heparin,the dosage and lab indexes.Results:The upper gastrointestinal bleeding is easy to happen in elderly patients with disease of digestive tract when using heparin in PCI.Conclusion:The patients before undergoing PCI,especially the elderly,need to have a general examination,make an overall assessment with care to digestive disease.Doctors should pay more attention to the heparin dosage and lab indexes in order to avoid serious complications.

Objective:To identify the influence of personality characteristics on adult patients' satisfaction after initial orthodontic treatment and offer references to rise quality of orthodontic treatment.Methods:85 patients(34 males and 51 females;average age 23.3years?4.4years who treated their teeth by fixed orthodontics were included in the study.Satisfaction questionnaire was used to assess the satisfaction with the dentition in the study sample.The NEO Five Factor inventory was used to assess personality profiles and traits in the study samples.Comparisons between groups were made by using Logarithm of likelihood ratio test.Results:This test provides a comprehensive assessment of personality according to the five major domains namely Neuroticism,Extroversion,Openness,Agreeableness and Conscientiousness.Satisfaction of higher neuroticism scores is relative low(P0.05).Conclusion:Different personality traits were found to be correlated with adult patients' satisfaction with their dentition during initial orthodontic treatment.The orthodontists should pay more attention to higher neuroticism scores adult patients during treatment.In according to strengthen the communication between the orthodontists and outpatients,the therapeutic effect of adult orthodontic treatment could be increased.

As the final step of the execution of the equipment purchase contract, acceptance check is very important for proper operation of the equipment.

Objective:To investigate the possibility and the usefulness of group psychological guidance in mental health education course. Methods:Two classes of the same grade were chosen,one was group psychological guidance class,and the other as control. SCL-90 was used to measure the effect of group instruction. Results:after group intervention, the study group decreased more in SCL-90 total score than control (24.5?7.2/13.4?2.5,t=6.24,P

A comparative observation of the quality of human immunoglobulin separated by the Rivanol-coldethanol combination method(R-E),the cold ethanol method(E)and the Rivanol-Ammoniumsulphate method(R-As)was performed.The experimental data and control data are as follows:Purityof immunoglobulin:96.67?0.93%(R-E,n=10);89.20?5.45%(E,n=8)and 96.22?0.67%(R-As,n=6).Proportion of IgG,IgA and IgM:89.26?0. 81%,6.29?0.38% and 1.16?0.28%(R-E,n=10);88.59?4. 87%,0.34?0.21% and 0.15%?0.09%(E,n=8)and 88.90?1.46%,7.08?1.28% and 0.24?0.29%(R-As,n=6)respectively.Proportion of IgG monomers and dimers,polymers,and fragments:95.96?1.38%,3.04?0.73% and 1.02?1.04%(R—E,n=7)and 98.43?0.57%,0.96?0.25% and 0.62?0.33%(E,n=3)respectively.All the preparations separated bythe three methods have been heated for 4 hours at 57℃,with their appearance being unchanged.