Objective To observe the effect of integrated traditional Chinese and Western medicine and rehabilitation therapy on the recovery of neurological function in patients with acute stroke.Methods 84 patients with acute stroke were randomly selected from January 2014 to November 2016 in our hospital and were randomly divided into observation group and control group,42 cases in each group,the control group were treated with combination of traditional Chinese and Western medicine treatment,the patients in the observation group were given rehabilitation therapy,compared two groups of patients effect of treatment.Results Before treatment,there was no significant difference in FMA,BI and NIHSS scores between the two groups; After treatment,the FMA,BI score of observation group were significantly higher than the control group(P<0.05),NIHSS score was significantly lower than the control group(P<0.05); the observation group patients quality of life significantly higher than that of the control group(P<0.05).Conclusion The combination of traditional Chinese and Western medicine and rehabilitation therapy can significantly improve the patient's limb motor function and overall neurological function,effectively improve the patient's daily life ability and quality of life.

mTOR exists in the variety of biological cells.The study showed in recent years that mTOR signaling pathway activation and tumor occurrence and development is closely related,and participate in many of the tumor cell proliferation and differentiation.including blood malignant tumora.Research shows that the inhibitor rapamycin and its derivatives,have anti-tumor effects.This reviewed the structure and function,signaling pathway of mTOR in the pathogenesis of leukemia the upper stream of the main adjustment factor and its inhibitors in the application of leukemia.

Objective To investigate the efficacy and cardiovascular disease of Danhong injection in the treatment after cardiac interventional therapy.Methods A total of 64 cases with cardiac intervention from September 2013 to July 2015 in our hospital were selected and divided into control group and experiment group with 32 cases in each group.Patients in the control group were given aspirin 100mg orally,and patients in the experiment group revieved Danhong injection 20mL intravenous drip qd,one times a day for 14 days.Two groups of patients underwent cardiac intervention.After the operaiton,the control group was given aspirin enteric-coated tablets 100mg orally,clopidogrel 75mg orally,and patients in the experiment group revieved Danhong injection 20mL intravenous drip qd,seven days for a course and the patients treated for three courses.The clinical efficacy,C-reactive protein(CRP),cardiac troponin T(TnT),P-selectin(Ps),PSGL-1,cardiovascular events(cardiovascular events),and adverse events were compared.Results After treatment,the clinical efficacy in experiment group was 93.75％,which significant higher than that in control group 71.88％,the difference was statistically significant(P<0.05).The rate of cardiovascular events in experiment group was 21.88％,which significant lower than that in control group 40.63％,the difference was statistically significant(P<0.05).The serum C-reactive protein,troponin T,Ps and PSGL-1 were significantly decreased in the two groups,and the experimental group was significantly smaller than the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions was 15.63％in the control group and 9.38％in the experimental group,the difference was not statistically significant.Conclusion Danhong injection treatment of elderly patients with cardiac intervention after the clinical effect is significant,high security,the incidence of cardiovascular events is low.

Objective: To develop titanium posted keeper removable magnetic attachment and to decrease its influence on magnetic resonance imaging(MRI). Methods: Pre fabricated soft magnetic alloy pin cap keeper(PSAPK), casting non precious alloycoping keeper(CNPAK), casting precious alloy coping keeper(CPACK), titanium post keeper(TPK) and titanium post(TP) were prepared and applied on the maxilla of a volunteer, MRI was taken and measured. Results: ①The attachments producing artifacts in MRI from the biggest to the smallest were listed in following rank: PSAPK, CNPAK, CPACK, TPK and TP. ②After removing the keeper from titanium post keeper, the post had no artifact on MRI. ③The artifact was the smallest taken with SE sequence. Conclusion: Titanium post keeper is an effective way to solve the artifact problem and will bring benefits to the patients who need MRI examination of head.

Objective To investigate the relationship between transient ischemic attack(TIA) and intracranial or extracranial artery stenosis.Methods Digital subtraction angiography (DSA) was further used in 56 cases with cerebral artery stenosis from 68 TIA patients after examinations of B ultrasound of neck, transcranial color doppler(TCD) and cardiac ultrasound. Results 6 cases were shown stenosis or occlusion in middle cerebral arteries(MCA), 21 cases were shown stenosis or occlusion in arteria carotis interna,8 cases were shown stenosis in subclavian arteries and 28 cases were shown stenosis or occlusion in vertebral arteries or basal arteries. 44 cases with TIA were related to stenosis of large arteties, 16 cases of which were intracarotid TIA, and 28 cases were vertebrobasilar TIA; 18 cases were embotic TIA, 15 cases of which were intracarotid TIA, and 3 cases were vertebrobasilar TIA. 4 casea were lacunar TIA; and 2 cases were related to vascular spasm. Conclusions Most patients with TIA have cerebral artery stenosis.There is a positive correlation between TIA and intracranial or extracranial artery stenosis.

Objective To investigate the clinical effect of Guizhi Fuling Capsule Combined with activating blood circulation to remove stasis to treat uterine fibroids.Methods 84 patients with uterine fibroids from June 2015 to October 2016 in our hospital were randomly selected and divided into experimental group and control group, 42 cases in each group.The control group was treated with Guizhi Fuling Capsule,and the experimental group was treated with blood activating and Stasis Removing Therapy on this basis of treatment.The patients were followed up for three months, and the clinical treatment effects of the two groups were compared and analyzed.Results The total effective rate of the experimental group was 97.6%,which was significantly better than the control group(76.1%), the difference was statistically significant(P<0.05);through the change of single symptom in two groups, it was found that there was no significant difference between the experimental group and the control group;The improvement rate of anemia, vaginal bleeding, abdominal pain, dysmenorrhea, menorrhagia in the experimental group was significantly higher than the control group, the difference between the two groups was statistically significant(P<0.05);The average volume of uterine fibroids in the experimental group was significantly lower than that in the control group, the difference was statistically significant(P<0.05).Conclusion Guizhi Fuling Capsule Combined with promoting blood circulation and removing blood stasis therapy has obvious effect and less adverse reaction.It can be used and popularized in clinic.

It is important to establish a simple method of culture in vitro to obtain purity oligodendrocyte. This paper introduced the re-searches about co-culture in vitro with rat cortical gliocyte, proliferation and differentiation of oligodendrocyte progenitor, differentiation of oligodendrocyte and identification of cell surface antigens at different stages of development.

To review the research of block copolymer micelles as delivery system for poorly soluble(antineoplastic) carrier over the last 10 years,including the composition,preparation methods and factors which influence the loading efficiency,physicochemical properties,and targeting characteristics of block copolymer micelles.Block copolymer micelles are self-assembled structures formed from amphiphilic block copolymers by dispersing in aqueous media.The hydrophilic blocks of the copolymer form the outer shell of the micelle,while the hydrophobic blocks form the inner core,and the proper coreshell micellar architecture was constituted.Block copolymer micelles have a whole set of unique properties,such as small sizes,narrow particle size distribution,high drug loading capacities,and available disposition characteristics in the body.Block copolymer micelles have been found as promising drug carriers due to making poorly soluble antineoplastic lysis,toxicities and side effects decrease,bioavailability increase,and targeting the drugs to specific sites in a passive way or attaching ligands in an active way,which can be specifically(recognized) by receptors onto the surface of copolymers.

Objective To investigate the risk factors associated with feeding intolerance in very low birth weight infants (VLBWI) and to investigate the beneficial factors for preventing feeding intolerance.Methods Retrospectively analysis was carried out in 151 VLBWI cases in our hospital from January 2005 to November 2010.Logistic regression analysis was performed to find the risk factors of feeding intolerance.Results The overall rate of feeding intolerance in VLBWI was 47.7 ％ (72/151).Dysporia and infection were associated with feeding intolerance in VLBWI (Wald x2 =7.748 and 4.555,P =0.05 and 0.033 respectively).Gender,multifetation were not associated with feeding intolerance(Ps ＞0.05).Conclusion The feeding intolerance is associated with dysporia and infection in VLBWI.