Objective To explore the value of multi-slice spiral CT (MSCT) with three dimensional (3D) postprocessing for assessing the lung volume and compare it with pulmonary function test (PFT). Methods In 60 cases, there were 34 healthy controls and 26 patients with emphysema. CT scan and PFT were performed within 3 d in all case. The total lung was respectively scanned at the end of full inspiration and full expiration, using GE Lightspeed 16 slices spiral CT. The total lung volumes and voxel index (VI) at threshold range of -1023 Hu to -900 Hu were measured by pulmonary quantitative software of AW4.2 workstation. Results The full expiration volume(Vex) significantly correlated with residual volume(RV) (r=0.908) as well as the full inspiration volume (Vin) with total lung capacity (TLC) (r=0.897). The value of (Vin-Vex) well correlated with forced vital capacity(FVC), as well as Vex/Vin with RV/TLC, VI Ain with TLC, VI Aex with RV. Conclusion Significant correlation of lung volume accessed by MSCT with 3D technique with PFT is useful for assessing the pulmonary function.

Purpose: To summarize the efficiency and the experience of the puncture aspiration and sclerosing therapy of hepatic and renal cysts. Materials and methods: 27 patients were treated with percutaneous aspiration and alcohol injection of the cystic cavity using 20G Greene needles. Among the 27 patients, 11 were with hepatic cyst, 15 with renal cyst, and 1 with polycystic kidneys. The size of cysts ranged from 3.5 to 12 cm, and the amount of aspirated fluid varied from 21 to 550ml. Pure alcohol (99. 7%) was injected into the cavities after apiration. Results: All the puncture procedures were successful, and no major complications occurred, The clinical symptoms were relieved or disappeared after the treatment. 18 cases were followed for 3 months to 5 years. The efficient indices: Grade I one case (polycystic kidneys), Grade Ⅱ 4 cases and Grade Ⅲ 13 cases. Conclusion: CT guided percutaneous puncture aspiration and sclerosing treatment of hepatic and renal cysts can be considered as an effective alternative to surgical treatment. The simple aspiration of polycystic kidneys is very helpful in relieving symptoms and improving renal functions.

Objective To create a further understanding of the angiographic features of the carotid artery pseudoaneurysm (CAPA) and to explore the clinical diagnostic value of angiography.Methods Sixteen cases of CAPA with clinical and angiographic data were analyzed retrospectively. The angiographic appearances in all of the patients were observed dynamically and precisely with a double blind method by two experienced radiologists together and formed a consensus interpretation. Results Angiography provided a definite diagnosis for all cases. The parent arteries included the common carotid artery (1 case), common carotid artery bifurcation (9 cases), internal carotid artery (5 cases) and external carotid artery (1 case). The angiographic features of the CAPA were: All cases showed the contrast media retension in the aneuysms; turblulent flow within aneurysm in 9 cases; the “jetting sign” at the leak of the parent artery in 7 cases; increase angulation of the bifurcation of internal and external carotid arteries in 12 cases.Conclusions Angiography is the most valuable examination method in diagnosis of CAPA, and it can not only provide definite diagnosis, but also play an important role in selection of therapeutic plan.

Objective To explore the value of angiographic diagnosis and interventional therapy for Takayasu arteritis. Methods Thirty-eight patients with Takayasu Arteritis (TA)(11 men, 27 woman; aged 8-54; average age, 30.5?18) undergone angiography were analyzed retrospectively. The angiographic appearances in all of the patients were observed dynamically in a double blind method by two experienced radiologists together and formed a consensus interpretation. Results According to the classification of Lupi-Herrea, typeⅠwas found in 11 cases, typeⅡin 15, typeⅢin 7 and typeⅣin 5 by angiography. Among 38 patients the arterial involvement ineluded subclavian artery in 20 cases (52.6%), the abdominal aorta in 15 cases (39.5%), the renal artery in 14 cases (36.8%), thoracic aorta in 10 cases (26.3%), carotid artery in 9 cases (23.7%), iliac artery in 9 cases (23.7%), axillary artery in 7 cases (18.4%), superior mesenteric artery in 4 cases (10.5%), coronary artery in 3 cases (7.9%), pulmonary artery in 3 cases (7.9%), and so on. Percutaneous transluminal angioplasty was performed in 22 cases and the stent placement was managed in 12 cases successfully. Conclusions Angiography is one of the ideal and reliable methods for the diagnosis and guidance of the interventional treatment for TA, and the latter is a mini-invasive and effective way for TA.

Objective To explore the value of imaging diagnosis on complications after kidney transplantation. Methods The radiologic appearances of 165 patients with postoperative complications were reviewed in a double blind method by two experienced radiologists. Results In the 158 patients with postoperative pulmonary infections, the main etiological causes according to their frequency were bacteria,fungus,virus,and so on. The postoperative pulmonary infections of the patients with renal transplantation were diagnosed as normal(28,17 7%),increased lung markings(44,27 8%) and pulmonary infection(84,53 2%) by chest X-rays and CT. The renal artery stenosis after kidney transplantation was diagnosed in 5 cases, and thrombosis of pancreas blood vessel after operation of simultaneous pancreas-kidney transplantation was diagnosed in 1 case by DSA. Conclusions Radiography and CT scan are very useful in the clinical diagnosis of postoperative pulmonary infections in the patients with renal transplantation,and radiography should be the first choice for the imaging diagnosis. DSA is one of the ideal and reliable measns to diagnose the postoperative vascular complications in kidney transplant recipients.

Objective To make a futher understanding of the CT features of primary carcinoma of vagina and to explore the clinical value of CT diagnosis of it.Methods Sixteen cases of primary cacinoma of vagina with clinical and CT data confirmed by pathology were analyzed retrospectively. The CT findings were observed in a double blind method by three experienced radiologists together and formed a consensus interpretation. Results The accurate rate of CT diagnosis for primary carcinoma of vagina was 81.3% in the 16 cases. There were 2 stage I, 6 stage II, 4 stage III and 4 stage IV lesions which were diagnosed by CT. The numbers of cases of the elevated type, ulcerative type and infiltrative type were 11, 3, and 2,respectively. The transcatherter internal pudendal arterial chemoembolization were successfully performed in 2 patients with vaginal carcinoma. Conclusion CT is not only a non-invasive method of detecting primary carcinoma of vagina,but also play an important role in differentiating the clinlcal phase and type of it. In more advanced stages of vaginal carcinoma, interventional therapy is chosen as the useful treatment to avoid exenterative surgery, preserve anatomy and function.

OBJECTIVE To make a further understanding of the imaging findings of the carotid artery pseudoaneurysm (CAPA) in head and neck and to explore the clinical value of imaging in diagnosis of it, especially the angiographic diagnosis. METHODS The clinical and imaging data of 36 patients with CAPA were analyzed retrospectively. The imaging appearances in all of the patients were observed by two experienced radiologists together and formed a consensus interpretation. RESULTS Imaging examination can establish definitive diagnosis in all cases. The parent arteries included the common carotid artery (2 case), common carotid artery bifurcation (18 cases), internal carotid artery (10 cases) and external carotid artery (2 cases). The imaging features of the CAPA were:the contrast media retained in the aneuysm in all cases;the aneuysm lumen with turbulent flow in 18 cases;the"jetting sign"at the leak of the parent artery in 14 cases;increase of bifurcation angles of internal and external carotid arteries in 24 cases. CONCLUSION Imaging examination is the most valuable examination method in diagnosis of CAPA, and it can not only make definitive diagnosis, but also play an important role in selection of therapeutic planning.

Objective To summarize the imaging features of neurofibromatosis.Methods Imaging data of 7 patients with neurofibromatosis proven by operation and clinical syndrome,were retrospectively analyzed.Results In 7 cases of neurofibromatosis,the findings of CT and MRI displayed 3 cases of bilateral vestibular schwannoma,2 of which were combined with optical nerve glioma;1 case of optical nerve glioma complicated with neurofibromatosis under cervical dura;1 case of meningioma and 2 cases with the changes of dura spinal sac.The last two cases displayed abnormal skull and spinal canal,concave change of vertebra and enlarged dura spinal sac,partially stretched to never root on CT plain flim and MRI.Conclusion Neurofibromatosis can be definitely diagnosed by optimal imaging examination based on comprehensive analysis of imaging features and typical syndromes.

BACKGROUND: Clinical researches found that portal vein occlusion was beneficial to inhibit growth of hepatocarcinoma, promote compensatory hyperplasia of un-blocking hepatic tissue and decrease metastasis of portal vein occlusion; however, it should be fu~her proved by animal experiments.OBJECTIVE: To investigate models of portal vein occlusion of hepatic VX2 tumor in rabbits and evaluate value of multi-slice CT.DESIGN: Randomized grouping design and animal study.SETTING: Department of Radiology, Xinqiao Hospital of the Third Military Medical University of Chinese PLA.MATERIALS: The experiment was carried out in the Imaging Department of Xinqiao Hospital of the Third Military Medical University of Chinese PLA from July 2002 to January 2005. Forty New Zealand rabbits were divided according to digital table into 4 groups: immediate group (transplantation of tumor after immediate portal vein occlusion), 3-week group (transplantation of tumor at 3 weeks after portal vein occlusion), negative control group and positive control group, 10 in each group.METHODS: Hepatic VX2 tumor was transplanted with abdominal-embedding innoculation at immediate portal vein occlusion and 3 weeks after portal vein occlusion. Meanwhile, they were divided into negative control group (Left external branch of portal vein was done sham-operative block,and left exite was embedded and inoculated pseudoly) and positive control group (Transplanted tumor did not suffer from portal vein occlusion). All rabbits were scanned with multi-slice CT.MAIN OUTCOME MEASURES: General changes of liver, changes of tumor, metastasis of tumor, vascular-imaging displaying rate of multi-slice CT of hepatic artery and portal vein, blood flow of liver, blood volume,mean transit time, permeability of vascular surface and fraction of hepatic arterial infusion (HAI).RESULTS: All 40 animals were involved in the final analysis. ① Tumor did not grow in both immediate group and 3-week group. In 3-week group,left endite was atrophied and growth of tumor was inhibited. The maximal diameter of tumor was smaller than that in positive control group [(2.55 ±0.46), (3.59±0.37) cm, t=5.57, P ＜ 0.001]. Incidences of metastasis in liver and lung were lower in 3-week group than those in positive control group (10%, 40%; 100%, 90%); however, there was no significant difference. ② Scanning with multi-slice CT, displaying rate of branches hepatic artery was lower in grade Ⅲ than that in grade Ⅰ and Ⅱ (40%, 70%,100%, P ＜ 0.05); but there was no significant difference of displaying rate of portal vein at various grades (P ＞ 0.05). ③ Values of blood flow of liver,blood volume, mean transit time and permeability of vascular surface were lower in immediate group and 3-week group than those in control groups,but values of HAI were increased.CONCLUSION: Ligating left external branch of portal vein is an ideal way to establish models of portal vein occlusion of hepatic VX2 tumor in rabbits; furthermore, multi-slice CT plays a key role in evaluating effect of portal vein occlusion.

Objective To analyze the status of blood supply at appearance of the first enhanced signal on dynamic contrast-enhanced MRI of hepatic cell cancer(HCC) of differentiated degree.Methods HCC was induced chronically with 1 ml of 2% DEN solution once a day in 80 rats for 14 weeks,and another 10 rats served as normal controls.All rats received dynamic contrast-enhanced MRI examination on week 16,18,20,21,22,23,24,25.The time-intensity curve was drawn and the slope rate of the first enhanced signal(S_(first)) was counted,then specimens were taken and observed of microvessel density(MVD) with light microscope.Results The differentiated degree of HCC was correlated with S_(first) and MVD.The poorer HCC differentiation,the bigger S_(first).Well differentiated HCC had low MVD,while poorly differentiated had higher MVD.Conclusion MVD is the main influence factor for that the S_(first) were significantly different between HCC of differentiated degree.