1.Assessment of lung volume using multi-slice spiral CT and comparison with pulmonary function test
Journal of Third Military Medical University 2003;0(09):-
Objective To explore the value of multi-slice spiral CT (MSCT) with three dimensional (3D) postprocessing for assessing the lung volume and compare it with pulmonary function test (PFT). Methods In 60 cases, there were 34 healthy controls and 26 patients with emphysema. CT scan and PFT were performed within 3 d in all case. The total lung was respectively scanned at the end of full inspiration and full expiration, using GE Lightspeed 16 slices spiral CT. The total lung volumes and voxel index (VI) at threshold range of -1023 Hu to -900 Hu were measured by pulmonary quantitative software of AW4.2 workstation. Results The full expiration volume(Vex) significantly correlated with residual volume(RV) (r=0.908) as well as the full inspiration volume (Vin) with total lung capacity (TLC) (r=0.897). The value of (Vin-Vex) well correlated with forced vital capacity(FVC), as well as Vex/Vin with RV/TLC, VI Ain with TLC, VI Aex with RV. Conclusion Significant correlation of lung volume accessed by MSCT with 3D technique with PFT is useful for assessing the pulmonary function.
2.CT Guided Puncture Aspiration and Sclerosing Treatrment of hepatic and Renal Cysts
Liguang ZOU ; Yong PENG ; Ken CHEN
Journal of Interventional Radiology 1994;0(02):-
Purpose: To summarize the efficiency and the experience of the puncture aspiration and sclerosing therapy of hepatic and renal cysts. Materials and methods: 27 patients were treated with percutaneous aspiration and alcohol injection of the cystic cavity using 20G Greene needles. Among the 27 patients, 11 were with hepatic cyst, 15 with renal cyst, and 1 with polycystic kidneys. The size of cysts ranged from 3.5 to 12 cm, and the amount of aspirated fluid varied from 21 to 550ml. Pure alcohol (99. 7%) was injected into the cavities after apiration. Results: All the puncture procedures were successful, and no major complications occurred, The clinical symptoms were relieved or disappeared after the treatment. 18 cases were followed for 3 months to 5 years. The efficient indices: Grade I one case (polycystic kidneys), Grade Ⅱ 4 cases and Grade Ⅲ 13 cases. Conclusion: CT guided percutaneous puncture aspiration and sclerosing treatment of hepatic and renal cysts can be considered as an effective alternative to surgical treatment. The simple aspiration of polycystic kidneys is very helpful in relieving symptoms and improving renal functions.
3.Expression of angiogenic factors in myocardial tissue of diabetic rats
Linlin CHEN ; Chun GUI ; Xiaomin WEI ; Liquan CHEN ; Liguang ZHU
Chinese Journal of Pathophysiology 2014;(6):1098-1102,1109
AIM:To observe the expression of angiogenesis factors in the myocardial tissue of streptozotocin-induced diabetic rats .METHODS:The diabetic rat model was induced by intraperitoneal injection of streptozotocin .After 12 weeks, the cardiac function was measured by MPA cardiac function analysis system .The myocardial collagen volume fraction ( CVF) was assessed by Masson staining .The capillary vessels was quantified as the ratio of capillary to myocyte (C/M) using CD31 immunostaining.The expression levels of vascular endothelial growth factor (VEGF), angiopoietin ( Ang)-1, endostatin and Ang-2 were observed by Western blotting .RESULTS:Compared with normal control group , the left ventricular end-diastolic pressure (LVEDP) was evidently increased (P<0.01), but left ventricular pressure rise maximum rate (+dp/dtmax), left ventricular pressure decrease maximum rate (-dp/dtmax) and the ratio of capillary/myo-cyte (C/M) were significantly decreased (P<0.05).The CVF and the expression level of endostatin were significantly increased, whereas the expression levels of VEGF and Ang-1 evidently decreased (both P<0.05) in diabetic rats.Howev-er, no marked difference in the expression of Ang-2 between the 2 groups was observed (P>0.05).CONCLUSION:Im-balances between the angiogenic factors (VEGF and Ang-1) and anti-angiogenic factors (endostatin) may play an impor-tant role in the pathogenesis of diabetic cardiomyopathy .
4.Health status of senior high school graduates living at urban or suburban areas in Beijing
Xuefei SHANG ; Xiaohong DENG ; Liguang SUN ; Shuo CHEN
Chinese Journal of Health Management 2014;8(2):106-109
Objective To compare health status of senior high school graduates living as urban vs suburban areas in Beijing.Methods Wilcoxon rank sun test,Ridit analysis and fuzzy mathematics synthesis were used to evaluate body shape index,physical function index and health defects indicator of 39 982 senior high school graduates in Beijing.Results A total of 9 117 urban boys,9 299 suburban boys,10 380 urban girls and 11 186 suburban girls were studied.For the boys,the urban was superior to the suburban areas in body shape index (Rurt=0.518,Rsub=0.482,P<0.05) and physical function index (Rurt=0.520,Rsub=0.480,P<0.05),and the urban was inferior to suburban areas in health defects indicator (Rurb=0.501,Rsub=0.554,P<0.05) and the composite index (Ruurb=0.484,Rsub=0.516,P<0.05).For the girls,the urban was superior to the suburban areas in physical function index (Rurb=0.562,Rsob=0.442,P<0.05),and the urban was inferior to the suburban areas in health defects indicator (Rurb=0.473,Rsub=0.523,P<0.05).The differences between urban and suburban areas tended to be of no statistical significance in body shape (U=5.79,P>0.05) and composite index (U=5.73,P>0.05).In fuzzy mathematics synthesis,the scores of urban boys,suburban boys,urban girls and suburban girls were 68.37,69.13,69.83 and 69.79,respectively.Conclusion Our investigation identified some differences in body shape index,physical function index and health defects indicator among senior high school graduates living at urban vs.suburban areas,although the differences of synthetical health were not statistically significant.
5.On reform of the curriculum systems and the teaching contents of higer vocational education of pharmacy
Liguang LIANG ; Chaodong LIAO ; Wenzhen NING ; Huadong LIU ; Haiyan CHEN
Chinese Journal of Medical Education Research 2006;0(09):-
According to the training objectives of higher vocational education of pharmacy and the requirements of employment knowledge and capability, the curriculum system can be divided into modular curriculum systems which correspond with the job posts. Additionally, a set of simulating practical curriculum systems with distinct characteristics should be established in line with the job posts. By means of the reform of curriculum systems and the overall optimizing of teaching contents, the overlapping and duplication in the existing curricula can be reduced and the teaching effects can be improved.
6.Observation on growth status of Blastocystis hominis in three media
Yingfang YU ; Xiuping WU ; Yanhong CHU ; Jiaxu CHEN ; Liguang TIAN
Chinese Journal of Schistosomiasis Control 2016;(1):51-53,65
Objective To observe the growth situation of Blastocystis hominis in vitro and select the optimal method for culti?vation of B. hominis in different media. Methods Ten positive stools with B. hominis were inoculated in three different media for cultivating,namely 1640,Jone’s medium and vitro medium. And the stools with good growth status and high quantities of B. hominis were chosen to inoculate in the three media with equal amount after subcultivation,and the number of B. hominis was counted every 24 h for ten days,and the morphological changes and growth status were also observed. Results The densities of B. hominis in the 1640 and Jone’s medium were higher than that in the vitro medium 48 h after the inoculation. The same stool sample was inoculated to the three different media and observed for ten days,and the results indicated that the growth of B. homi?nis presented regular changes in the three media,the growth peaks were on the third,sixth and ninth day post inoculation;and the density of B. hominis was the highest in the Jone’s medium. The morphology of B. hominis was the clearest and most dynamic in the vitro medium,while various reproductive forms were observed in the Jone’s medium. Conclusion Jone’s medium is suitable for the growth of B. hominis and can be the first choice for the cultivation of B. hominis in vitro,and vitro medium is the best medium for observing the growth situation of B. hominis.
7.Study of Stomach Using Ferric Oxide Suspension as Oral Contrast Agent in MRI
Jian YAO ; Weiling GUI ; Liguang CHEN ; Bin ZHAO
Journal of Practical Radiology 2001;0(01):-
Objective To evaluate the applied value superparamagnetic Ferric Oxide oral contrast agent in the dignosis of MR forstomach.Methods Ferric Oxide Suspension was administered before MR scanning of stomach in 36 cases,ranged in age form 21 to 60 years old.MR findings were analysed.Results The fullness of stomach was 100% after administration of Ferric Oxide Suspension.Stomach canal appeared as negative contrast in all MR sequences,the relation between lesions in stomach and around tissue were clearly showed.During MRCP,it could restrict the high signal in stomach canal.Conclusion Oral Ferric Oxide Suspension as contrast agent during MR examination of stomach is easily accepted by patients,it is a safe and steady negative contrast agent for gastrointestinal MR examination.
8.Double chemoembolization of hepatic carcinoma by TACE and portal vein PCS
Liguang ZOU ; Ken CHEN ; Yueyong QI ; Jing MA ;
Journal of Third Military Medical University 2003;0(16):-
Objective To study the method and efficacy of double chemoembolization of hepatic carcinoma by transcatheter arterial cheomembolization (TACE) and portal vein port catheter system (PCS). Methods PCS was implanted in portal vein in 17 cases of irresectable primary hepatocellular cancer (HCC) during operation. One month later, chemoembolization of portal vein via PCS was performed, meanwhile TACE was also done (hepatic arterial portable vein chemoembolization, HA PVCE). A total of 120 cases of HCC treated simply with TACE were served as the control. Results The technical success rate was 100% in both TACE and portal vein PCS. Hepatic arteriography showed rich or moderate blood supply of HCC in 134 cases and PCS portography showed tumor staining in 6 cases. In groups of HA PVCE and TACE, the positive alpha fetoprotein (AFP) level decreased in 80% and 71.6% cases; half a year survival rate was 85.7% and 74.4%, and one year survival rate was 71.4% and 52.4%, respectively. Conclusion Double chemoembolization by TACE and portal vein PCS is a safe procedure with high technique success rate and therapeutic efficacy for irresectable hepatic carcinoma.
9.Reflection on the implementation of continuing medical education by using both domestic and foreign medical imaging websites
Song ZHANG ; Li CHEN ; Qichuan ZHANG ; Ping LIU ; Liguang ZOU
Chinese Journal of Medical Education Research 2017;16(3):310-313
With the development of computer network technology,network teaching has become an important mode of continuing medical education.There are many kinds of medical imaging websites from both domestic and foreign.In general,they can be divided into three main categories,in terms of society official websites,academic journal websites,and educational resource websites.On the basis of the introduction of the representative domestic and international medical imaging websites,this paper analyzes the advantages and disadvantages of them,and emphasizes some measures to improve the application value of them in continuing medical education,including to establish an authoritative academic website to achieve continuing medical education credits,to strengthen the resources and function of various medical image sites,and to promote intelligent and personalized self-learning,etc.We hope the combination of medical imaging websites with continuing medical education will be much closer,so as to provide a good platform for imaging personnel to improve their professional level and scientific research ability.
10.Examination of gastric carcinoma with CT virtual gastroscopy using bi-tilted CT scanning
Yueyong QI ; Liguang ZOU ; Shuhua DAI ; Qingrong SUN ; Tie CHEN ; Lin CHEN
Chinese Journal of General Surgery 2001;0(09):-
Objective To investigate the procedure,imaging features and clinical significance of CT virtual gastroscopy(CTVG) in the diagnosis of gastric carcinoma using bi-tilted CT scanning.Methods Thirty patients and ten normal volunteers had bitilted CT scan using helical CT(GE lightspeed 16 CT).The patients and yolunteers were given bubble-making powder by mouth and placed in a supine position on the CT table.CTVG and MPR images were obtained using the virtual dissection and reform of GE.Results The appearances of the inner lesion and normal wall of the stomach on CTVG were similar to those on fiberoptic gastroscopy.The CTVG and MPR features of gastric cancer were focal or diffuse mural thickening,soft tissue mass,stenosis of stomach,cancerous ulcer,infiltration to adjacent tissues,and lymph node and distant metastases.In comparison with fiberoptic gastroscopy(as the gold standard),CTVG showed a diagnostic accuracy of 92.5 %,a sensitivity of 93.3 %,a specificity of 90.0 %,a positive prediction value of 96.7 %,and a negative prediction value of 81.8 %.Conclusions CTVG is a safe,reliable,non-invasive method for demonstrating the structure of normal and abnormal stomach,and is a good complementory method to conventional fiberoptic gastroscopy.