1.The development and application of an encapsulated aneurysm clip with biomembrane graft across the vessels.
Songtao QI ; Wenqing ZHANG ; Wenfeng FENG ; Guofeng XU ; Lijin HUANG ; Jun FAN ; Zhuang CHEN
Journal of Biomedical Engineering 2008;25(3):699-702
The external wrapping of intracranial aneurysm is the definitive treatment of choice for surgical clipping or endovascular occlusion, yet there may exist considerable difficulties and risks because so far neither ideal wrapping techniques nor ideal wrapping materials have been obtained. An encapsulated aneurysm clip with biomembrane graft across the vessels is introduced in this article. By clipping the neck and wrapping the sack of aneurysm simultaneously, this clip successfully solves the problems of unreasonable encapsulated materials and techniques; it has been proved to be an effective method for treating intracranial refractory aneurysms.
Equipment Design
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Humans
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Intracranial Aneurysm
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surgery
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Ligation
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instrumentation
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Neurosurgical Procedures
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instrumentation
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Vascular Surgical Procedures
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instrumentation
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methods
3.Endoscopic mucosal resection with a ligation device for early gastric cancer and precancerous lesions: comparison of its therapeutic efficacy with surgical resection.
Hyun Soo KIM ; Dong Ki LEE ; Soon Koo BAIK ; Jun Myoung KIM ; Sang Ok KWON ; Dae Sung KIM ; Mee Youn CHO
Yonsei Medical Journal 2000;41(5):577-583
Endoscopic mucosal resection with a ligation device (EMR-L) has become important in the curative treatment of precancerous lesions and early gastric cancers (EGCs), but little is known of the long-term efficacy and survival rates of EMR-L compared with surgical resection. We analyzed the therapeutic efficacy and safety of EMR-L in cases of EGC and precancerous lesions and compared the results of EMR-L with those of gastrectomy in patients with EGC over the same periods. EMR-L was performed on 20 EGCs and 54 precancerous lesions including tubular adenomas with or without severe dysplasias in 74 patients. Macroscopic type, size and location of the lesion were determined by endoscope, and the depth of invasion in EGCs was determined by endoscopic ultrasonography and confirmed by pathologic examination of the resected specimens. All the EGC cases were endoscopically followed up for at least 18 months (range, 18-66 months). Patients were selected that underwent subtotal gastrectomy and the survival rates were compared with those that underwent EMR-L. Complete resection was made in a single EMR-L treatment session in 61 cases (82.4%; 91.5%, were precancerous lesions and 65% were EGCs). After a repeat trial of EMR-L, the total rate of complete resection of precancerous lesions and EGCs was 92.6% and 85.0%, respectively. The survival rate of EGCs showed that complete resection by EMR-L resulted in 2 and 5 year survival rates of 100% and 95%, which are comparable to those of surgery (100% and 100%). This study suggests that EMR-L is a technically simple, minimally invasive and highly safe and effective treatment modality for selective EGCs, and offers an alternative to surgical treatment.
Adult
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Aged
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Aged, 80 and over
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Comparative Study
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Endoscopy, Digestive System*
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Female
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Gastrectomy
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Human
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Ligation/instrumentation*
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Male
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Middle Age
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Precancerous Conditions/surgery*
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Stomach Neoplasms/surgery*
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Time Factors
4.Development of a multiple ligator and its endoscopic therapy for patients with esophageal varices.
Feng QI ; Qi-zhen QUAN ; Zi-qin SUN ; Yao-jun WANG ; Xue-liang JIANG
Chinese Journal of Medical Instrumentation 2002;26(2):129-130
The ligators we have developed is a kind of economical and effective six-ring ligator. Endoscopic variceal ligation (EVL) was performed to treat bleeding from esophageal varices in patients with liver cirrhosis using self-made ligator and foreign multiple ligator. There are similar effects with both self-made ligator and foreign mutiple ligator in the control of variceal bleeding, variceal obliteration and rebleeding (93.8%, 87.5%, 0 in the group with self-made ligator, 94.5%, 87.1%, 2.4% in the group with foreign multiple ligator, P>0.05). In terms of the quality index, successful operation rate, hemastatic rate, variceal obliteration rate, rebleeding rate, complications and variceal recurrence rate, the self-made ligator is as good as the foreign multiple ligator, but much cheaper.
Adolescent
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Adult
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Child
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Endoscopes
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Equipment Design
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Esophageal and Gastric Varices
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therapy
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Female
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Gastrointestinal Hemorrhage
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therapy
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Humans
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Ligation
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instrumentation
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methods
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Liver Cirrhosis
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complications
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Male
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Middle Aged
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Treatment Outcome
5.The initial approach of two sides hypogastric artery ligation and isolation with laparoscope before excision of presacral tumor.
Tong-Wei CHU ; Yue ZHOU ; Ping LIANG ; Shao-Jun ZHANG ; Jian WANG ; Xia ZHANG ; Nian-Chun ZHANG ; Chang-Qing LI ; Yong HAO ; Yong PAN
Chinese Journal of Surgery 2008;46(1):41-43
OBJECTIVETo observe the significance of excision of presacral tumor after two sides hypogastric artery ligation and tissue dissociation with laparoscope.
METHODSTwenty-one patients with sacral tumor were performed excision of presacral tumor after two sides hypogastric artery ligation and tissue dissociation with laparoscope.
RESULTSAll sacral tumor were removed successfully, the mean volume of operative blood was 800 ml (range 500-1900 ml), and all the patients were followed up 3-25 months, averaged time 11 months. One patient was recurred after 2 months of operation (the patient was Ewing's sarcoma, and refused to accept radiotherapy and chemotherapy after operation), 1 patents died of brain metastases after 9 months of operations. There were no recurrence in the others patients.
CONCLUSIONSThe excision of presacral tumor after two sides hypogastric artery ligation and tissue dissociation with laparoscope is an effective operation method, with the advantages of decreasing the operative blood and difficulty of sacral tumor excision, and diminishing the operation wound.
Adolescent ; Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Iliac Artery ; surgery ; Laparoscopes ; Ligation ; instrumentation ; methods ; Male ; Middle Aged ; Retrospective Studies ; Sacrum ; Spinal Neoplasms ; surgery ; Treatment Outcome ; Young Adult
6.Clinical Outcomes of Ahmed Glaucoma Valve Implantation Using Tube Ligation and Removable External Stents.
Jong Joo LEE ; Ki Ho PARK ; Dong Myung KIM ; Tae Woo KIM
Korean Journal of Ophthalmology 2009;23(2):86-92
PURPOSE: To investigate the immediate and long-term outcomes of Ahmed glaucoma valve (AGV) implantation with silicone tube ligation and removable external stents. METHODS: This retrospective non-comparative study investigated the outcomes of AGV implantation with silicone tube ligation and removable external stents in 95 eyes (90 patients) with at least 12 months of postoperative follow-up. Qualified success was defined as an intraocular pressure (IOP) of < or =21 mmHg and > or =6 mmHg regardless of anti-glaucoma medication. Those who required additional glaucoma surgery, implant removal or who had phthisis bulbi were considered failures. Hypotony was defined as an IOP of <6 mmHg. RESULTS: Mean IOP reduced from 37.1+/-9.7 mmHg preoperatively to 15.2+/-5.6 mmHg at 12 months postoperatively (p<0.001). Qualified success was achieved in 84.2% at 1 year. Hypotony with an IOP of <6 mmHg was seen in 8.4% and an IOP of <5 mmHg in 3.2% on the first postoperative day. No case of hypotony required surgical intervention. Suprachoroidal hemorrhage did not occur in this study. When stents were removed on the first postoperative day because of an insufficient IOP decrease, the mean IOP decreased significantly from 42.0 mmHg to 14.1 mmHg (p<0.001) after 1 hour. The most common complication was hyphema, which occurred in 17.9%. CONCLUSIONS: Hypotony-related early complications requiring surgical intervention were reduced by ligation and external stents in the tube. In addition, early postoperative high IOPs were managed by removing external stents. The described method can prevent postoperative hypotony after AGV implantation and showed long-term success rates comparable to those reported previously.
Equipment Design
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Female
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Filtering Surgery/*instrumentation
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Follow-Up Studies
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Glaucoma/physiopathology/*surgery
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*Glaucoma Drainage Implants
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Humans
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Intraocular Pressure
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Ligation/instrumentation
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Male
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Middle Aged
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Retrospective Studies
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*Silicone Elastomers
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*Stents
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Time Factors
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Treatment Outcome
7.A modified method for inducing periodontitis in dogs using a silk-wire twisted ligature.
Se Eun KIM ; Eui Ri LEE ; Yesran LEE ; Manbok JEONG ; Young Woo PARK ; Jae Sang AHN ; Jeong Taek AHN ; Kangmoon SEO
Journal of Veterinary Science 2012;13(2):193-197
This study was designed to assess the effectiveness of a modified silk ligature twisted with wire for inducing advanced periodontitis. Periodontitis was induced in five premolars and one molar of 20 healthy dogs over a 60-day period. The dogs were divided into four groups according to the ligature-inducing materials used: soft moistened food only, wire ligature (WL), silk ligature (SL) and twisted ligature with silk and wire (SWL). Periodontal indices were recorded, and dental radiographs were taken before and after 60 days of ligation. The ligatures were checked daily and the day the ligature fell out was noted. The period during which the ligatures were maintained was significantly shorter for the SL group compared to the SWL group (p < 0.05). Results of the clinical examination showed that almost all periodontal status parameters including the plaque index, gingival index, clinical attachment level, and bleeding on probing were significantly exacerbated in the SWL group compared to the other groups (p < 0.05). Radiographic evaluation demonstrated that alveolar bone levels were significantly lower in the SWL group than the other groups on day 60 (p < 0.05). These results suggested that experimental periodontitis induced by SWL could be an effective method for investigating periodontitis in canine models.
Alveolar Bone Loss/veterinary
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Analgesics, Opioid/therapeutic use
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Animals
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Dog Diseases/*pathology
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Dogs
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Ligation/instrumentation/methods/*veterinary
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Materials Testing/veterinary
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Pain/drug therapy/veterinary
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Periodontitis/pathology/*veterinary
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Tramadol/therapeutic use
8.Transumbilical single-port laparoscopy combined with improved double hernia needles for pediatric hydrocele.
Jin-Chun QI ; Wen-Yong XUE ; Suo-Lin LI ; Bao-Sai LU ; Jiang-Hua JIA ; Yan-Ping ZHANG ; Lei DU ; Meng LI ; Wei LI
National Journal of Andrology 2016;22(9):809-812
ObjectiveTo compare the clinical effect of transumbilical single-port laparoscopy combined with improved double hernia needles with that of traditional open surgery in the treatment of hydrocele in children.
METHODSWe retrospectively analyzed 35 cases (54 sides) of pediatric hydrocele treated by transumbilical single-port laparoscopy combined with improved double hernia needles (laparoscopy group). We recorded the operation time, intraoperative blood loss, hospital stay, scrotal edema, and postoperative complications and compared them with those of another 46 cases (58 sides) treated by traditional open surgery (open surgery group) during the same period.
RESULTSThe laparoscopy group showed a significantly shorter operation time, less intraoperative blood loss, milder scrotal edema, and fewer hospital days than the open surgery group (all P<0.05). However, no statistically significant difference was found in the incidence of postoperative complications between the two groups (P>0.05). Subcutaneous emphysema developed in 2 patients in the laparoscopy group, which disappeared after 1-3 days of oxygen inhalation and other symptomatic treatment, while scrotal hematoma occurred in 1 and incision fat liquefaction in 2 patients in the open surgery group 3 days postoperatively, which healed after debridement suture and daily dressing, respectively. The patients were followed up for 3-6 months, which revealed no late complications in the laparoscopy group but 1 case of unilateral recurrence and 2 cases of offside recurrence in the open surgery group, all cured by laparoscopic internal ring ligation.
CONCLUSIONSTransumbilical single-port laparoscopy combined with improved double hernia needles is superior to traditional open surgery for the treatment of pediatric hydrocele and therefore deserves clinical generalization.
Blood Loss, Surgical ; Child ; Edema ; diagnosis ; Female ; Humans ; Laparoscopy ; instrumentation ; methods ; Length of Stay ; Ligation ; Male ; Needles ; Operative Time ; Postoperative Complications ; diagnosis ; surgery ; Postoperative Period ; Recurrence ; Retrospective Studies ; Scrotum ; Subcutaneous Emphysema ; etiology ; Testicular Hydrocele ; surgery ; Umbilicus