Objective: To analysis HIV infection status among volunteer blood donors in Shaoxing area from 2001 to 2014, and to provide evidence for recruiting strategy of volunteer blood donors. Methods: A statistical analysis was conducted on the confirmed HIV-positive cases of volunteer blood donors from 2001 to 2014 in Shaoxing area. Results: 36 volunteer blood donors were confirmed anti-HIV positive, and the positive rate was 0.09‰. Only 1 volunteer blood donor was confirmed anti-HIV positive before 2006, and the HIV-positive rate rose and the changes in volatility after 2006. The HIV-positive rate in Zhuji was highest compared to other blood center of Shaoxing. The HIV-positive rate in male and female were 4.14∶1, men who had sex with men remain at great risk for HIV infection. Conclusions Anti-HIV positive rate was lower among volunteer blood donors in Shaoxing area. Since 2006 years, anti-HIV positive rate increased. The anti-HIV positive rate were different in the different blood center in Shaoxing area, HIV antibody confirmatory positive is more common in young males volunteer blood donors.

【Objective】 To evaluate the screening efficacy and practical value of the portable microfluidic biochemical analyzer in the detection of blood donors before blood donation. 【Methods】 Blood donor samples, clinical blood samples and constant quality control products were collected. Referring to the documents of ISO15189 and National Health Industry Standard, the precision and accuracy of hemoglobin (Hb) and alanine aminotransferase (ALT) were verified and compared with other detection systems. 【Results】 The MS200 biochemistry instrument has an intra-batch precision of 1.40% to 1.46%, inter-batch precision of 1.91% to 1.94%, and correctness bias of -0.9% to -1.3% for Hb test, and an intra-batch precision of 3.77% to 4.86%, inter-batch precision of 4.92% to 6.02%, and correctness bias of -3.0% to -4.8% for ALT test, which were within the range of quality requirements of industry standard. Comparison of Hb test results between MS200 biochemistry and Hb201 analyser on 1 189 peripheral blood samples from donors showed no statistically significant difference (P>0.05). 65 samples showed positive correlation between MS200 biochemistry and XS-900i automated hematology analyzer on Hb test results (R²=0.986, P=0.000). Correlation analysis of all the results of ALT detection by MS200 biochemical analyzer and AU480 biochemical analyzer in 1 065 samples showed a positive correlation (R²=0.965, P=0.000). The elevated ALT samples did not affect the Hb test results, and the samples with abnormal Hb value did not affect the ALT test results, with no interference between the two items in the detection. 【Conclusion】 The MS200 biochemical analyzer based on microfluidic technology has reliable methodological performance and can meet the need of pre-donation testing.