1.Proceedings of the 2002 annual meeting of Chinese orthopedic trauma association
Chinese Journal of Orthopaedic Trauma 2002;0(03):-
The 2002National Annual Meeting org anized by the newly founded Chinese Orthopedic Trauma Association was held in Shenzhen in J une,with attendance of 180surgeons.Leaders of Chinese Orthopedic Society and many senior professors from the o rthopedic field also attended the me eting.The major topics of this 3-day meeting were“pelvic &acetabular fractures”and“open fractures”.5orthopedic trauma experts coming from Germany and US were invited to give pr esentations at the first day symposium,with the topics about radiologic al diagnosis,surgical approach and su rgical techniques of pelvic &acetab ular fractures.Precious experiences were exchanged in trauma resuscitation,management of open fractures and man agement of infection of bone and join t.225articles were received for this m eeting,with the contents covering e very part of the skeletal system.Clinically,the treatments reported at the meeting involved modern orthopedic surgical techniques and experiences in non -operative management.As for the basic research,application of tissue e ngineering in the orthopedic field w as discussed.45articles selected for oral presentation covered the management of pelvic &acetabular fractur es,choice of internal or external fixation in treatment of proximal femoral fractures,soft tissue management i n bone and joint infections,and clinical tria ls in the treatment of scapular fractures,proximal humeral fractures,d istal radial fractures and calcaneal fractures.The articles received also revealed that the methods adopted in clinical research should be improved and standardized in China so as to promote better natio nal comparison and exchange.[
2.Assessment of the methods used to analyze the clinical outcomes in 180 clinical reports in orthopaedic trauma
Chinese Journal of Orthopaedic Trauma 2002;0(03):-
Objective To assess the methods used to analyze the clinical outcomes in recent 180c linical reports in orthopaedic trauma in Chi na.Methods Statistical analysis was done with t he collection of the papers of2002Symposium of Chinese Orthopedi c Trauma Association in the aspects o f their research scope,object,case number,fracture classification,c riterion of follow -up and application of statistics.Results Of the total 225papers received by the symposium,180were clinical reports which reported more than ten thousand cases.The s cope of reports was wide and included majo r current methods of fracture treatm ent.The papers with statistical analysis were only 6.1%.Fracture classifica tions and criteria of follow up were v aried without a standard.No prospec tive report was found.Conclusion Current methods in clinical study on orthopaedic trauma should be improv ed.[
3.Clinical study of enteral nutrition support with low carbohydrate formula in severe traumatic brain injury patients with hyperglycemia
Chuanmei WANG ; Lidan XU ; Xiaoyan LAI
Parenteral & Enteral Nutrition 1997;0(04):-
Objective: To investigate the treatment effect of rational enteral nutrition in hyperglycemia after severe brain injury.Methods: 60 patients were randomly divided into control group and study group.The control group was given homogenized diet and the study group was given low carbohydrate formula.Blood glucose,ALB,K+,Na+,Cl-,TG,TC were measured before and after therapy.Results: After the nutrition treatment,patients biochemical indices of fasting blood-glucose,blood sugar 2 hours after meal in study group were significantly lower than control group(P
4.Effect of comprehensive health intervention on serum lipids in obese children
Lidan XU ; Xishao LIU ; Chuanmei WANG ; Xiaoyan LAI
Chinese Journal of Clinical Nutrition 2009;17(6):346-348
Objective To evaluate effect of comprehensive health intervention on serum lipids in obese children.Methods Totally 67 obese children (obesity group) who were treated in Baoan People's Hospital re-ceived one-year comprehensive health interventions. Another 65 normal-body-weighted children were recruited as control group.The changes of body height,weight,BMI,blood pressure (BP),and serum lipids were recorded before and after interventions.Results Compared with the control group,the weight,BMI,BP,TG,and LDL-C in the obesity group significantly decreased (P<0.05 or P<0.01).The BMI,BP,and TG in the obesity group were significantly improved after intervention (P<0.05 or P<0.01).HDL-C was significantly higher than the pre-intervention level (P<0.05),while was significantly lower than that in the control group (P
5.Application of fiber bronchoscopy with three-way laryngeal mask airway continuous ventilation in 1-6 month old infants with oxygen-dependent respiratory disease
Jie GUO ; Zhipeng JIN ; Qi WANG ; Lidan CUI
Journal of Clinical Pediatrics 2015;(7):641-644
ObjectiveTo discuss the values of fiber bronchoscopy with three-way laryngeal mask airway continuous ventilation in 1-6 month old infants with oxygen-dependent respiratory diseases.MethodsFrom January 2010 to May 2011, 29 cases of 1-6 month old infants with oxygen-dependent respiratory diseases who underwent conventional ifber bronchoscope and 148 cases of 1-6 month old infants with oxygen-dependent respiratory diseases who underwent ifber bronchoscopy with three-way laryngeal mask airway continuous ventilation were enrolled in control and treatment groups respectively. The success rate of ifber bronchoscope and the incidence rate of complications were compared between two groups.ResultsIn the treatment group, the success rate of ifber bronchoscope was 89.2% which was signiifcantly higher than 58.6% in the control group and the rate of laryngeal edema was 9.1% which was signiifcantly lower than 35.3% in the control group. The rates of endotracheal intu-bation ventilation and postoperative hemorrhage were lower than those in the control group, but the difference was not statistical ly signiifcant.ConclusionFiber bronchoscopy with three-way laryngeal mask airway continuous ventilation is superior to the traditional ifber bronchoscope in 1-6 month old infants with oxygen dependent respiratory system diseases.
6.Thalidomide inhibits TGF-?1-induced transdifferentiation of human fetal lung fibroblast cell line to myofibroblast
Zhi WANG ; Lidan ZHAO ; Xuan ZHANG ; Fulin TANG ; Mengxue YU
Basic & Clinical Medicine 2006;0(01):-
Objective To investigate the effects of Thalidomide(THD)on transdifferentiation of human fetal lung fibroblast(HFL-F) to myofibroblast(MF) induced by Transforming Growth Factor-?1(TGF-?1) and the effects on trans differentiated MF.Methods HFL-F to MF trans-differentiation was induced with 5 ?g/L TGF-?1.The effect of 50 ?g/L THD on HFL-F to MF transdifferentiation was evaluated by measuring hydroxyproline(HYP) content with alkaline hydrolysis colorimetry,?-smooth muscle actin(?-SMA) protein with Western Blot,?-SMA and collagen Ⅲ(COL Ⅲ) mRNA with semiquantitative RT-PCR.Results THD inhibited TGF-?1 induced up-regulation of HYP and COLⅢ mRNA expressions(all P0.05).For HFL-F treated with 5 ?g/L TGF-?1 for 96 h,THD inhibited COLⅢ mRNA expression(P
7.The interventional treatment of complex lymphatic malformation in children
Lidan WANG ; Sui HUANG ; Fan LIU ; Qi MA ; Yu CHEN
Chinese Journal of Radiology 2017;51(6):441-445
Objective To explore the interventional treatment method for complex and refractory lymphatic malformation in children.Methods The clinical data of 78 cases with complex and refractory lymphatic malformation during January 2013 to January 2016 in our department were retrospectively analyzed.The lesions involved the neck in 28 cases,maxillofacial regions in 19 cases,the chest and armpit in 8 cases,the limb in 7 cases,the pelvic cavity and retroperitoneal space in 6 cases,the superior mediastinum in 3 cases,the hypogloeeis in 3 cases and scrotum or perineum region in 4 cases.All the children underwent ultrasound or MRI imaging studies preoperatively.The interventional procedures included:(1) Percutaneous puncture of the LM for sclerotherapy.The lesions were punctured with 20 G needle under the guidance of DSA or ultrasound and the correct positions were confirmed with angiography.The liquid of the lesions was extracted as far as possible.The dosage of sclerosing agents was adjusted according to the size of lesion.The dose of Laurolacrogol injection was 1/10—1/5 of the amount of the liquid in the lesions and the maximum of Laurolacrogol foam was ≤8 ml(20 mg).The dose of Pingyangmycin was ≤ 8 mg.(2) The drainage catheter placement and sclerotherapy.Percutaneous catheter drainage under ultrasound guidance or by surgery was conducted.The liquid in the lesions was drained by retaining the catheter for 1-4 weeks,and sclerotherapy was applied for several sessions during this period.(3) Treatment for one time a week,2 times a session.The interval of every two sessions was 4 weeks.The sclerosing agents included:Laurolacrogol Injection or Pingyangmycin for the lesions with high tension,Laurolacrogol foam for the lesions with low tension,Pingyangmycin for the microcystic lesions.Statistical analysis was conducted using SPSS20.0 software.Results A total of 208 sessions of sclerotherapy for 78 LM patients were performed and average session was (3.0±0.8).Nine patients used Lauromacrogol foam,23 patients used Lauromacrogol Injection,39 patients used pingyangmycin,while combined treatment was conducted in 7 patients.Laurolacrogol injection was used in 20 cases,Pingyangmycin in 29 cases and combination therapy in 5 cases for the high tension lesions in the neck,maxillofacial,chest and armpit.The low tension lesions of pelvic cavity and retroperitoneal space in 6 cases and of superior mediastinum in 3 cases were placed with draining catheters,and treated with sclerotherapy with Laurolacrogol foam.Three cases with hypogloeeis LM was neonates,who were treated with Laurolacrogol injection.The lesions on the limb and scrotum or perineum region were almost microcystic,were treated with Pingyangmycin in 9 cases and with combination therapy in 2 cases.The total curative rate was 97.4% (76/78),total effective rate was 100% (78/78).Imaging examinations showed that the cavities were closed or only a small amount of residual sclerotic lesions were present.Clinical examinations showed that the surface masses almost disappeared.The follow up period was 6 months to 2 years.There were no serious complication and adverse reactions occurred.Conclusions Interventional treatment is a safe,effective,and minimally invasive treatment for the complex and refractory lymphatic malformation.In order to receive the best treatment effect,we should use targeted therapy for different region and type of LM.
8.Application of pulse indicator continuous cardiac output monitoring in the fluid management of children with acute respiratory distress syndrome
Zhipeng JIN ; Qi WANG ; Jun SU ; Lidan CUI ; Yibing CHENG
Chinese Journal of Applied Clinical Pediatrics 2017;32(6):439-441
Objective To explore the application value of pulse indicator continuous cardiac output (PiCCO) monitoring in the fluid management of children with acute respiratory distress syndrome (ARDS).Methods Thirty-two children with ARDS admitted to Pediatric Intensive Care Unit(PICU) of Zhengzhou Children's Hospital,from April 2013 to April 2016,were divided into intervention group (15 cases) and control group (17 cases) by adopting random number table method.Fluid management of intervention group by PiCCO,control group by central venous pressure,the 2 groups' oxygenation index (OI),acute lung injury score,mechanical ventilation time and 28 days mortality were statistically compared.The categorical data were analyzed by using SPSS 11.0 software,and the t test was used for the measurement data.The categorical data and mortality comparison were analyzed by adopting x2 test.The difference was statistically significant at P < 0.05.Results After 3 days of mechanical ventilation,the changes of OI in the intervention group were significantly higher than those in the control group [(175.0 ±-43.7) mmHg vs.(143.0 ± 42.8) mmHg (1 mmHg =0.133 kPa),t =2.090 0,P < 0.05].The intervention group was significantly shorter than the control group [(10.45 ± 3.12) d vs.(12.63 ± 2.87) d,t =2.058 7,P < 0.05].There was no significant difference between 2 groups in acute lung injury score,PICU length of stay and 28 days mortality (all P > 0.05).Conclusions PiCCO monitoring and guidance in the fluid management of pediatric ARDS can improve oxygenation after 3 days,reduce mechanical ventilation time,but can not significantly reduce the 28-day mortality.
9.Clinical analysis of severe complications after percutaneous dilational tracheostomy in patients of Neuro-surgery Department
Yueqiao XU ; Weitao CHENG ; Ning WANG ; Wenjin CHEN ; Lidan JIANG
Clinical Medicine of China 2016;32(10):947-949
Objective To analyze the clinical characteristics and treatment Methods of severe com?plications after percutaneous tracheotomy( PDT) in neurosurgery patients,and to provide reference for the treat?ment and rescue of these patients. Methods A retrospective analysis of 578 cases after PDT was performed in Neurosurgery Intensive Care Unit ( NSICU ) of Xuanwu Hospital of Capital Medical University from 2005 to 2015. The types of complications,treatment method and prognosis were analyzed. Follow?up was 3 months to 1 year. Results Eighteen cases with severe complications,including bleeding,wound infection,asphyxia caused by tracheal mucosa suffocation,airway stenosis caused by granulation tissue,subcutaneous emphysema and neu?momediastinum,etc. After treatment and active rescue,most patients recovered,no patients die directly associated with surgery. Conclusion PDT plays an important role in the treatment of patients in NSICU,but it is still pos?sible to have serious complications,so physicians must understand and be prepared for complications,and pay more attention to prevent poor prognosis.
10.Comparative study of enteral and parenteral nutrition support in critically ill patients
Chuanmei WANG ; Lidan XU ; Meifang JIANG ; Xiaoyan LAI
Parenteral & Enteral Nutrition 1997;0(03):-
Objective: To compare the effect of enteral and parenteral nutrition on critically ill patients. Methods: 48 patients with critically ill in ICU were randomly divided into EN group and PN group.The nutritional index and the complication were compared between groups. Results: The levels of Hb,TP and ALB were significantly increased after EN,and the rates of complications in PN group were higher in PN group than that in EN group. Conclusion: Compared to parenteral nutritional support,enteral nutritional support can improve the nutritional condition and have less complications in critically ill patients.