1.Effects of electroacupuncture on the elderly's postoperation cognitive dysfunction after general anesthesia
Wei ZHOU ; Jinyan QU ; Yaoxiong CHEN ; Furong LUO ; Xiaojie LIU ; Licheng CHEN
Chinese Journal of Physical Medicine and Rehabilitation 2014;36(5):372-375
Objective To study the effects of electroacupuncture (EA) on the elderly's postoperation cognitive dysfunction (POCD) after general anesthesia.Methods Patients who need to have surgical operation done for lumbar spinal stenosis were randomly divided into an observation group (electroacupuncture and routine intravenous anesthesia) and a control group (only routine intravenous anesthesia),and EA was administered to those in the electroacupuncture group for 30 minutes at an interval of 10 minutes,beginning at 30 minutes prior to routine intravenous anesthesia and lasted till the end of the surgery.The differences regarding intraoperative propofol and remifentanil dosage,cognitive function,the levels of serum interleukin-6(IL-6),interleukin-10 (IL-10) and S100-β were compared.Results The intraoperative propofol and remifentanil dosages in observation group were (6.54 ± 3.27) μg/(kg· h) and (3.67 ± 2.53) mg/(kg· h),respectively,while those in control group were (9.70 ± 4.82) μg/kg and (5.62 ± 1.73) mg/kg.The intraoperative propofol and remifentanil dosages in observation group were significantly lower than those in control group (P < 0.05).At 72 hours post-operation the incidence of POCD in observation group was significantly lower than that in control group (1 case,2.5% versus 8 cases,20%),while the MMSE score was higher in observation group than that in control group (25.7 ± 1.9 versus 23.2 ± 2.1).The post-operation level of serum IL-6,IL-10 and S100-β in observation group were significantly lower than that in control group (P < 0.05).Conclusion Electroacupuncture could significantly improve the elderly's postoperation cognitive dysfunction after general anesthesia.It could inhibit the excessive expressions of IL-6,IL-10 and S100-β,alleviate the brain damage and reduce the incidence of POCD.
2.A case report of mixed epithelial stromal tumor of male kidney
Lintao CAO ; Licheng QU ; Jiufeng TAN
Chinese Journal of Urology 2023;44(9):702-703
Mixed epithelial and stromal tumors of the kidney (MESTK) are very rare in male kidney tumors. One case was reported in this article. The patient accidentally discovered a renal space occupying lesion during physical examination and underwent laparoscopic radical left nephrectomy. The postoperative pathological results were reported as MESKT, with immunohistochemical staining of ER (+ ), PR (+ ), SMA (+ ). After a follow-up of 4 months, the results showed that the patient had no signs of tumor recurrence or related complications.
3.Standard Comparison of Toxicological Test Methods for Cosmetics(II)
HE Licheng ; SANG Jing ; XIE Zhen ; QU Linji ; KANG Hua ; KUANG Rong
Chinese Journal of Modern Applied Pharmacy 2023;40(16):2224-2230
“Measures for the Administration of the Registration and Recordation of Cosmetics” classified new cosmetic raw materials, setting a systematic and detailed request list for new raw materials registration and recordation. This paper sorted out the requirements and compared domestic and foreign standards for acute oral toxicity test, subchronic oral toxicity test and combined chronic toxicity/carcinogenicity test, providing comments and suggestions on current standards.
4.Standard Comparison of Toxicological Test Methods for Cosmetics(Ⅲ)
Zhen XIE ; Linji QU ; Jing SANG ; Jinsong ZHANG ; Xiaopeng ZHANG ; Licheng HE ; Rong KUANG
Chinese Journal of Modern Applied Pharmacy 2024;41(7):957-961
China has become the world's second largest consumer market for cosmetics. The rapid development of the cosmetics industry requires that its regulatory management and standard and regulation also need to keep pace with the times and constantly improve. This paper compares domestic and foreign standards for skin sensitisation test, skin phototoxicity test and skin photoallergy test, and analysis the specific problems of the current standards and make recommendations.