1.Three Cases of Lichen Nitidus Associated with Various Cutaneous Diseases.
Eun Byul CHO ; Heung Yeol KIM ; Eun Joo PARK ; In Ho KWON ; Kwang Ho KIM ; Kwang Joong KIM
Annals of Dermatology 2014;26(4):505-509
Lichen nitidus (LN) is an uncommon, usually asymptomatic cutaneous eruption characterized by the presence of multiple, small, flesh-colored papules. The epidemiologic and pathophysiologic characteristics of LN have not yet been defined. Furthermore, LN has rarely been described in association with other cutaneous diseases. We herein report 3 cases of LN associated with various cutaneous diseases, including lichen striatus, oral lichen planus, and psoriasis vulgaris.
Lichen Nitidus*
;
Lichen Planus
;
Lichen Planus, Oral
;
Lichens
;
Mouth
;
Psoriasis
2.A Case of Oral Lichen Planus Improved after Tacrolimus Mouth Rinse Treatment.
Young Chae LEE ; Sook ja SON ; June Hyunkyung LEE ; Tae Young HAN
Korean Journal of Dermatology 2017;55(7):475-476
No abstract available.
Lichen Planus, Oral*
;
Mouth*
;
Tacrolimus*
3.Benefits of Screening for Oral Lichen Planus.
Gian Paolo BOMBECCARI ; Francesco SPADARI ; Aldo Bruno GIANNÌ
Annals of Dermatology 2016;28(6):779-780
No abstract available.
Lichen Planus, Oral*
;
Mass Screening*
5.Three Cases of Oral Lichen Planus Treated with Topical Tacrolimus.
Korean Journal of Dermatology 2006;44(4):521-523
Oral lichen planus (OLP) is a painful chronic inflammatory condition, that is often resistant to many therapeutic approaches, including immunosuppressive agents. Topical tacrolimus has recently been recognized as a safe and effective remedy in the treatment of OLP. We, rerein, describe 3 patients with oral lichen planus, who showed a substantial improvement after the use of topical tacrolimus ointment (0.1%). This topical agent was well tolerated in all 3 patients and could be used an effective medicine in controlling oral lesions of lichen planus.
Humans
;
Immunosuppressive Agents
;
Lichen Planus
;
Lichen Planus, Oral*
;
Tacrolimus*
6.Perforating Lichen Nitidus Associated with Oral Lichen Planus.
Eun Byul CHO ; Young Wook LEE ; Eun Joo PARK ; In Ho KWON ; Hee Jin CHO ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Dermatology 2010;48(11):1012-1015
Lichen planus is an unique, common inflammatory disorder that affects the skin, mucous membranes, nails and hair. Oral lichen planus is among the more common mucosal conditions with an unknown etiology. Lichen nitidus is an uncommon, usually asymptomatic cutaneous eruption that is characterized by the presence of multiple, small, flesh colored papules. Perforation in lichen nitidus is a rare phenomenon. Lichen nitidus is distinguished from lichen planus on both clinical and histologic grounds. However, the possibility that lichen nitidus represents a micropapular variant of lichen planus has never been definitively excluded. Herein, we report on a case of perforating lichen nitidus associated with oral lichen planus.
Hair
;
Lichen Nitidus
;
Lichen Planus
;
Lichen Planus, Oral
;
Lichens
;
Mucous Membrane
;
Nails
;
Skin
7.Significance of cell immunoreactions and cell apoptosis in oral lichen planus.
Guan-hong DENG ; Zuo-liang CHEN ; Hong-bai CHEN ; Jun CHENG
West China Journal of Stomatology 2009;27(3):256-259
OBJECTIVETo evaluate the expression of CD4+, CD8+ T cells and cell apoptosis in oral lichen planus (OLP) and investigate the role and the relationship of immunological reaction and cell apoptosis in the pathogenesis of OLP2.
METHODSImmunohistochemical technique was used to study the expression of CD4+, CD8+ T cells in 27 OLP cases. TUNEL was used for detecting the cell apoptotic index (AI) in 17 OLP2 cases.
RESULTSThe expression of CD4+, CD8+ T cells were obviously elevated in lamina propria of OLP group compared with control group (P<0.05). There was a strong significance when compared the ration of CD4/CD8 in both group. AI was remarkably increased in epithelia cells and significantly decreased in lymphocytes in lamina propria in OLP cases compared with its expression in the control group respectively.
CONCLUSIONThe increased amount of CD4+, CD8+ T cells in lamina propria of OLP and the change ration of CD4/CD8 suggest that immune response is involved in the pathogenesis of OLP. The abnormal cell apoptosis plays an important role in the pathogenesis of OLP.
Apoptosis ; Epithelial Cells ; Humans ; Lichen Planus, Oral
9.A Case of Squamous Cell Carcinoma Originating from Oral Lichen Planus.
Bo Ri KIM ; Sang Young BYUN ; Jin Ho CHUNG ; Kwang Hyun CHO
Korean Journal of Dermatology 2015;53(8):635-637
Oral lichen planus (OLP) is a relatively common chronic inflammatory disease of uncertain etiology. OLP lesions rarely undergo spontaneous remission and have the potential to undergo malignant transformation. The risk of malignant transformation in OLP is estimated to be between 0.4% and 5.3%; two clinical studies in Korea reported the frequency of malignant change as 2.9% and 2.85%. However, to the best of our knowledge, there has been no individual case report in the Korean dermatological literature to date regarding the malignant transformation of OLP. Herein, we report the case of a 77-year-old Korean woman with long-standing OLP that underwent transformation to oral squamous cell carcinoma. This is the first well-documented case report of squamous cell carcinoma that developed from OLP.
Aged
;
Biopsy
;
Carcinoma, Squamous Cell*
;
Female
;
Humans
;
Korea
;
Lichen Planus
;
Lichen Planus, Oral*
;
Remission, Spontaneous
10.The Relationship between Anger Expression and Its Indices and Oral Lichen Planus
Masoumeh MEHDIPOUR ; Ali TAGHAVI ZENOUZ ; Alireza FARNAM ; Rana ATTARAN ; Sara FARHANG ; Maryam SAFARNAVADEH ; Narges GHOLIZADEH ; Saranaz AZARI-MARHABI
Chonnam Medical Journal 2016;52(2):112-116
Oral lichen planus (OLP) is a common inflammatory disease with unknown etiology. Depression, stress and anxiety are psychological factors that their influence on the expression of lichen planus by affecting the immune system's function has been confirmed. There is a probable relationship between anger and OLP expression. Therefore, the present study aimed to evaluate the association of "anger" and OLP. In this descriptive study 95 subjects were included in 3 groups. A: patients with oral lichen planus, B: positive control, C: negative control. Anger and its indices were assessed by the State-Trait Anger Expression Inventory-2 (STAXI-2) questionnaire, and pain was measured via the Visual Analogue Scale (VAS). The collected data were analyzed statistically using SPSS 18 software. The lichen planus and positive control groups bore higher total anger index (AX index) values compared with the negative control. Comparing anger expression-in (AXI) among the lichen planus and negative control groups revealed higher grades in lichen planus group. Evaluating the pain severity index (VAS) data and anger indices in lichen planus group, Spearman's Rank Correlation Test revealed a significant correlation between TAngR (reactional anger traits) and pain severity. The findings of this study indicated that there was a significant correlation between anger control and suppression of lichen planus development. On the other hand, the patients with more severe pain mostly expressed their anger physically. Based on the findings, we can make the claim that anger suppression and its control-in (gathering tension) may play a role in the development of lichen planus as a known psychosomatic disorders.
Anger
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Anxiety
;
Depression
;
Hand
;
Humans
;
Lichen Planus
;
Lichen Planus, Oral
;
Psychology
;
Psychophysiologic Disorders
;
Visual Analog Scale