The authors studied depression, using Zung's Self-Rating Depression Scale (SDS) in the subjects of 3,499 male and 1,335 female college freshmen of Yeungnam University. The authors collected the reports of SDS during the periods from January to February, 1986, and applied ANOVA and t-test on depression scores in order to compare them between various psychosocial factors, and sexes. The results are as follows: There was significant difference in the mean averages of total depression scores between male and female students: male students scored 35.68+7.46, female students scored 38.93+7.26 (P<0.01). The depression scores relating to the items of indecisiveness, psychomotor retardation, decreased libido, and diurnal variation were relatively higher in both groups. One hundred and sixty-one male students (4.6%) showed seriously high degree depression scores of 50 or higher, while one-hundred and seventeen female students (8.8%) showed the same scores. Female students attending in liberal arts showed higher level of depression scores (P<0.01). There was a strong tendency toward higher depression scores in the students who were dissatisfies with their home atmosphere, college, department and familiarity of parents and those who had pessimistic views of self in the past, present or future in both groups (P<0.001).
Atmosphere ; Depression* ; Female ; Humans ; Libido ; Male ; Parents ; Psychology ; Recognition (Psychology)

This study was carried out to develop a Korean language version of Zung's self-rating depression scale (SDS). The subjects consisted of 173 males and 161 females drawn from various groups of the general population by a cluster of sampling methods. In order to analyze the data on depression scores, Pearson's product moment correlation coefficient method was carried .out, as well as reliability and factor analysis, by the SPSS/PC+ program. The results obtained were as follows: The mean average of the total depression scores were 40.60. 8.66 for the subjects. Thirty-seven subjects (11.1%) showed high depression scores of 50 or over. Test-retest reliability(coefficient r=0.82, p <0.001), internal consistency(coefficient r=0.84, p <0.001) were satisfactory. Factor analysis using oblique technique rotation yielded five factors. The items of confusion, indecisiveness, decreased libido, diurnal variation, and psychomotor retardation were scored higher by the subjects. The items of suicidal rumination, psychomotor agitation, constipation, irritability, and weight loss were scored lower.
Constipation ; Depression* ; Female ; Humans ; Libido ; Male ; Psychomotor Agitation ; Weight Loss

The frequency of sexual dysfunction from rectal cancer operation has been reported with wide range from 8 to 86%. We have performed prospective study to analyze the cause of sexual dysfunction after operation in rectum which is anatomically adjacent to cavernous nerve and artery The study was done from April 1991 to March 1992 with 26 patients who were neurologically normal before the radical rectal surgery. To study intraoperative vascular damage, we performed duplex doppler sonography of penile arteries preoperatively and on tenth postoperative day. To study neurologic insult urodynamic study was performed preoperatively, tenth postoperative day and postoperative sixth month, and subjective sexual history was obtained preoperatively and postoperative sixth month. There was no evidence of change in the diameter and peak velocity of cavernous artery on penile duplex sonography and penile rigidity, implying no vascular damage. Fourteen patients (53%) complained of sexual dysfunction in postoperative sixth month. Subjective sexual dysfunction showed no correlation with age, stage, mode of operation, tumor size, tumor location from anal verge and intraluminal position of the tumor. We couldn't find any association between postoperative decreased libido and decreased self-esteem from stoma, which confirms that psychologic cause does not seem to ascribe to erectile dysfunction. Patients with neurologic deficit were 21(81%) on tenth postoperative day, but only 4(17 %) out of 23 who were followed up to postoperative sixth month. This suggests that recovery of sexual dysfunction was delayed or impossible, compared with rapid recovery of bladder dysfunction. This also suggests additional intraoperative nerve damage along cavernous nerve pathway. In conclusion, sexual dysfunction after rectal cancer operation was not caused by vascular damage nor psychologic etiology. Nerve damage is rather highly suggested, but there was no correlation with stage and mode of operation.
Arteries ; Erectile Dysfunction ; Humans ; Libido ; Male ; Neurologic Manifestations ; Prospective Studies ; Rectal Neoplasms* ; Rectum ; Urinary Bladder ; Urodynamics

Clinical observation was done on 300 cases of chronic prostatitis who visited Urologic Department. Korea University Hospital during the period of 24 months from January 1, 1976 to December 31, 1977. The results are summarized as follows. 1. The age distribution was between I9 and 65, while 55 percent of total cases belonged to the age group of 20 to 29. 2. The decreased libido was complained in 3l cases (10.3%) of chronic prostatitis, among them, 22 cases be1onged to married group. while 9 cases to unmarried group. Among the married group, 17 patients including S patients who had had vasectomy previously were between the age of SO and 49.3. Asymptomatic cases were found in 4S patients (14.3%), while many others had vague symptoms such as urethral discomfort. urethral discharge. pain on urination and perineal discomfort. 4. The past history of nonspecific urethritis were found in the l58 cases (52.7%). The duration of the infection was between l month to 6 months in 84 cases (53.1%), and between 13 months to 24 months in 49 cases (3l%). 5. Urinalysis were within normal limits in 229 cases (76.3%). Microscopic examination of prostatic fluid and urine shred wag done in all cases and in 249 cases (83%) revealed the presence of infection.
Age Distribution ; Humans ; Korea ; Libido ; Prostatitis* ; Single Person ; Urethritis ; Urinalysis ; Urination ; Vasectomy

PURPOSE: Chronic prostatitis is characterized by various symptoms. To elucidate the prevalence of such symptoms, we developed a questionnaire composed of six pain-related, seven sex-related, and 11 voiding-related questions and evaluated chronic prostatitis patients under 50 years of age. MATERIALS AND METHODS: From March 1995 to July 1996, a total of 500 patients (prostatitis 303, prostatodynia with history of prostatitis 153, prostatodynia only 44) underwent study. The mean age was 35 years and the average duration of infliction was 3.5 months. RESULTS: Perineal, testicular, and penile pains were the most often complained types of perceived pains. The most frequently complained voiding symptoms were frequency, weak stream, residual urine sensation and dribbling which were seen in over 40% of the patients. More than 50% of the patients responded as having some type of voiding difficulty. For sexual symptoms, premature ejaculation , decreased libido and orgasm, decreased potency, and pain associated with ejaculation were seen in 64%, 55%, 54%, and 47% of the patients. When the prostatitis and prostatodynia patients were compared to one another to find out any characteristic symptoms of prostatitis, there was no difference in pain but statistically significantly higher response was observed in ejaculation associated pain and a decrease in orgasm in the prostatitis group. CONCLUSIONS: Our data have helped to elucidate the characteristics of symptoms in prostatitis patients, and the questionaire can be used as a tool to standardize prostatitis symptoms, and to evaluate treatment responses.
Ejaculation ; Humans ; Libido ; Male ; Orgasm ; Premature Ejaculation ; Prevalence* ; Prostate* ; Prostatitis ; Surveys and Questionnaires ; Rivers ; Sensation

Apart from sleep wake disorders, nowadays, modafinil is being prescribed for several psychiatric disorders including depression. Despite being reported as to be having very low abuse potential, cases of modafinil dependence had come to the limelight. In this case report, we describe a 35 year old man with bipolar affective disorder while in remission who developed modafinil dependence and later on, had hypersexuality when he increased the dose of modafinil from 400 to 1,000 mg/day. Existing literature suggests that modafinil when taken above prescribed doses can cause many side effects ranging from nausea, vomiting to psychotic exacerbation and mania. However, hypersexuality as a side effect of modafinil overuse is not commonly seen. The exact pathophysiological mechanism of modafinil induced hypersexuality is not clear. Clinicians should be aware of possibility of modafinil leading to dependence and this rare significant side effect of modafinil.
Bipolar Disorder ; Depression ; Libido ; Mood Disorders ; Nausea ; Sleep Wake Disorders ; Substance-Related Disorders ; Vomiting

PURPOSE: This study was conducted to investigate the relationship between serum total testosterone levels and scores on the Aging Male's Symptom (AMS) scale and the International Index of Erectile Function (IIEF) in men with erectile dysfunction with testosterone deficiency syndrome (TDS). MATERIALS AND METHODS: From January 2005 to July 2008, 134 patients who complained of sexual dysfunction such as erectile dysfunction or decreased libido as the main symptoms of TDS with serum total testosterone levels less than 3.5 ng/ml were evaluated by independent t-test and linear regression analysis, respectively. Patients with treated hypogonadism within 6 months, with a history of taking a PDE5 inhibitor or an antidepressant for a depressive disorder, or who had metabolic syndrome were excluded from this study. RESULTS: The AMS scale and its 3 subdomain scores were not significantly correlated with the total testosterone level. By contrast, the total IIEF score and the score of each IIEF domain except sexual desire showed a weakly significantly positive correlation with serum total testosterone. CONCLUSIONS: In TDS patients with erectile dysfunction, there was a low relationship between serum total testosterone levels and the AMS scale and a weakly positive correlation between total testosterone levels and all IIEF domains except sexual desire. There was a low relationship between the AMS scale, the sexual desire domain score of the IIEF, and total testosterone. We should understand these limitations when evaluating patients with erectile dysfunction with TDS. New scales should be developed for the evaluation of erectile dysfunction in these patients.
Aging ; Depressive Disorder ; Erectile Dysfunction ; Humans ; Hypogonadism ; Libido ; Linear Models ; Male ; Sorbitol ; Testosterone ; Tyramine ; Weights and Measures

OBJECT: Risperidone, unlike other atypical antipsychotics, is thought to elevate prolactin levels. This paper examines the relationship of risperidone-induced hyperprolactinemia and the sexual dysfunctions of the patients in the real clinical practice. METHODS: Forty nine patients (male 22, female 27) with 6 month-over risperidone medication were assigned and serum prolactin was assayed in serum by radioimmunometric assay. In the distinction of sex, six adverse events possibly associated with increased prolactin levels were determined by interviewing the patients (poor erection, ejaculatory dysfunction, galactorrhea, decreased libido, orgasmic dysfunction and obesity in male;amenorrhea, vaginal dryness, galactorrhea, decreased libido, orgasmic dysfunction and obesity in female). RESULTS: In 49 patients, thirty six patients (male 15;56%, female 21;95%) showed hyperprolactinemia and twenty two patients (male 13;48%, female 8;36%) had sexual side-effects. Both risperidone dosage per day and duration were not correlated with prolactin levels and adverse events. There was no significant direct correlation between serum prolactin levels and sexual adverse events. CONCLUSION: The risperidone-associated increase in serum prolactin levels was not significantly directly correlated with the emergence of possible prolactin-related adverse events in the real clinical practice. However, our results suggest that risperidone-induced hyperprolactinemia may play a role in sexual dysfunction of female patients.
Antipsychotic Agents ; Female ; Galactorrhea ; Humans ; Hyperprolactinemia* ; Libido ; Obesity ; Orgasm ; Pregnancy ; Prolactin ; Risperidone

In contrast to previous dogma, the decline in testosterone levels in postmenopausal women is thought to be age-related and not a specific function of the menopause. In addition to normal aging, many conditions affecting ovarian and adrenal function, factors leading to increased SHBG levels can decrease androgen levels below the physiologic range in women. Clinical symptoms of female androgen deficiency include a loss of libido, lack of well-being, and persistent fatigue. However, the diagnosis of female androgen deficiency, as recently provided by the Princeton consensus statement, is under debate due to several limitations. Testosterone therapy in postmenopausal women with symptoms suggestive of androgen deficiency remains controversial. The adverse effects of testosterone therapy appear to be low in incidence, but more studies are necessary to assess long-term safety. Therefore, the decision to treat or not to treat androgen deficiency in postmenopausal women must be carefully considered on an individual basis by comprehensive evaluation of potential benefits and risks.
Aging ; Consensus ; Fatigue ; Female ; Humans ; Incidence ; Libido ; Menopause ; Risk Assessment ; Testosterone

Ninety-one cases of chronic prostatitis were studied endoscopically and the results were evaluated. Endoscopic appearance of the bladder neck in the presence of chronic prostatitis was classified as 1. Normal bladder neck, 16 cases (17.5 per cent) 2. Elevated posterior urethra, 8 cases (8.7 per cent) 3. Contracture of the neck, 19 cases (20.8 per cent) 4. Diffuse, irregular swelling and narrowing of the neck, 19 cases (20.8 per cent) 5. Reversed V-neck, 2S cases (31.8 per cent) In this study it was found that the bladder neck was abnormal in 82.1 per cent of the cases. In 36 instances or 39.5 per cent. the verumontanum appeared normal but abnormal in 55 cases or 60.5 per cent. Bilateral prostatic urethral walls were inflammatory in 57 cases and unilaterally inflammatory in 6 cases. Forty-two cases (46.1 per cent) revealed elevation of the posterior urethra and the prostatic urethral floor was hyperemic and edematous in 44 cases. In 40 cases (43.9 per cent), the normal bladder mucosa was observed, trabeculation and cellulation in 43 cases and trigonal and interureteric thickening in 7 cases were also observed. Decreased libido was present in 12 instances (33.3 per cent) of 36 cases having normal verumontanum and in 25 instances (45.4 per cent) of 55 cases having abnormal one. Urinary symptoms were most frequently positive in cases with bladder neck contracture. The results of treatment using Ultzmann's urethral syringe were evaluated as follows: Complete cure was obtained in 8 cases (19.5 per cent) almost complete cure in 14 cases (34.1 per cent), improvement in 15 cases (36.5 per cent) and no remarkable change in 4 cases (9.7 per cent). Five cases had transurethral resection and four achieved almost complete cure and one improved clinically. Subjective symptoms were completely relieved in 23 cases (56.1 per dent) and more than two thirds of the previous symptoms were gone in 18 cases (43.9 per cent) after treatment. In summary. endoscopic examination on chronic prostatitis is s worthwhile and important procedure in establishing therapeutic criteria.
Contracture ; Endoscopy ; Libido ; Mucous Membrane ; Neck ; Prostatitis* ; Syringes ; Urethra ; Urinary Bladder