Objective To study and analyze the functional electrical stimulation therapy compliance of patients with paralysis of limb movement disorder and its influence factors. Methods A total of 168 patients with paralysis of limb movement disorder from December 2014 to August 2016 were selected as the research object, and the treatment compliance of all the patients were evaluated, then the treatment compliance of patients with different gender, ages, education degree, social support degree, disease course, treatment cognition, psychology state, pecuniary condition, living conditions and medical insurance situation were compared too, then the relationship between those study factors and treatment compliance of these patients were analyzed by the Logistic regression analysis. Results One hundred and four cases of 168 patients with paralysis of limb movement disorder with higher treatment compliance of functional electrical stimulation therapy, the rate was 61.90%,the treatment compliance of patients with different gender, ages, education degree, social support degree, disease course, treatment cognition, psychology state, pecuniary condition, living conditions and medical insurance situation all had obvious differences, and those study factors all had close relationship to the treatment compliance of these patients by the Logistic regression analysis, all P<0.05. Conclusions The functional electrical stimulation therapy compliance of patients with paralysis of limb movement disorder still need to be improved, and its influence factors are more, so they should be paid to targeted intervention according to these influence factors.

To analyze the genetic characterization of epidemic rubella virus strains isolated in Liaoning from 2007-2012, a total of 145 rubella virus strains were isolated using Vero/Slam cell line from the patients' throat swabs during rubella outbreaks and sporadics cases in Liaoning Province from 2007 to 2012. Fragments of 945 nucleotides containing 1E gene from 145 rubella virus isolates were amplified by RT-PCR, the PCR products were sequenced and analyzed. Based on the 739 nucleotides of 1E gene, the phylogenetic trees were constructed with 32 WHO rubella reference strains of 13 genotypes downloaded from GenBank and 145 rubella virus strains. The results showed that the 145 rubella virus strains in 2007 -2012 belonged to genotype 1E, nucleotide acids and amino acids similarities were 97.2%-100.0% and 97.6%-100.0%, respectively. Compared to the 1E reference strains(Rvi/ Dezhou.CHN/02, RVi/MYS/01), the nucleotide acids and amino acids similarities were 96.6%-99.2% and 98.2%-100.0%, respectively except for one amino acid change (Val246-Ala246) of RVi/Shenyang. Liaoning. CHN/13.11/13, and Asp262-Asn262 of RVi/Shenyang. Liaoning. CHN/13.11/4 and RVi/Liaoyang. Liaoning. CHN/26. 11/2. there had no change found in the important antigenic epitope sites, the hemagglutination inhibition and neutralization epitopes of the other rubella viruses. All the 145 strains isolated had the same amino acid change (Leu338--Phe338) in E1 protein. These findings suggested that genotype 1E of rubella virus was the predominant genotype in Liaoning province. the rubella prevailed in recent six years was mainly caused by rubella viruses genotype 1E with multi-transmission routes.
Amino Acid Sequence ; China ; epidemiology ; Epidemics ; Genotype ; Humans ; Molecular Sequence Data ; Phylogeny ; Rubella ; epidemiology ; virology ; Rubella virus ; classification ; genetics ; isolation & purification ; Sequence Alignment ; Viral Envelope Proteins ; chemistry ; genetics