1.Development of B-ultrasonic wave video image acquisitionand management system
Liaojun CHEN ; Xiaoying BAI ; Siyuan DONG
Chinese Medical Equipment Journal 1989;0(02):-
This paper introduces the development of B-ultrasonic wave video image acquisition and management system based on Windows of the PC.With the application of VB6.0,the acquisition and dynamic display of B-ultrasonic wave video image are realized.ACCESS taken as the database and its ADO application set up,the system has the functions of query,statistics and report of B-ultrasonic wave video image.
2.Clinical effect of Total Saponins of Panax Pseudoginseng on unstable angina pectoris
Gangjun ZONG ; Jingkai CHEN ; Liaojun ZHOU
Journal of Medical Postgraduates 2005;0(S1):-
Objective: To study the effects of Total Saponins of Panax Pseudoginseng injection on unstable angina pectoris (UAP) . Methods :Forty-eight cases of UAP patients were randomly divided into Total Saponins of Panax Pseudoginseng injection treatment group and routine treatment group. The serum levels of plasminogen activator inhibitor (PAI), soluble intercellular adhesion molecule-1 (SICAM-1) and C-reactive protein (CRP) after two weeks treatment in two groups were observed. Results:The total effective rate was significantly higher in Total Saponins of Panax Pseudoginseng injection treatment group than in control group. The indexes of PAI after Total Saponins of Panax Pseudoginseng injection treatment were lower. The levels of SICAM-1 and CRP were lower in Total Saponins of Panax Pseudoginseng injection treatment group than those in control group. Conclusion:Total Saponins of Panax Pseudoginseng injection is an effective drug for UAP, and it obviously improves fibrinolytic activity and relieves inflammatory reaction.
3.Effects of methionine-induced hyperhomocysteinemia on protein C,antithrombin-Ⅲ and von willebrand factor
Jingkai CHEN ; Liaojun ZHOU ; Manqing CHEN ; Qiuliang ZHAO
Chinese Journal of Pathophysiology 2000;0(11):-
AIM: To observe the effects of methionine-induced hyperhomocysteinemia on protein C(PC), antithrombin-Ⅲ (AT-Ⅲ) and von willebrand factor (vWF). METHODS:Eighteen New Zealand rabbits were randomized as methionine group (group M,n=9) and control(group C,n=9), which were fed with methionine-rich diet(600 mg/d) and regular diet respectively for sixteen weeks.By the end of sixteen weeks,the serum biochemistry and PC,AT-Ⅲ and vWF in plasma were determined and vWF expression of endothelial cells of aorta were examined.RESULTS:In group M, the levels of methionine(29.97?5.34 ?mol/L) and homocysteine(13.30?2.19 ?mol/L) in serum were signifficantly higher than those(14.48?1.97 ?mol/L and 5.36?1.19 ?mol/L, respectively,P
4.Oxidative modification of low density lipoprotein induced by hyperhomocysteinaemia following application of methionine
Jingkai CHEN ; Qiuliang ZHAO ; Liaojun ZHOU ; Manqing CHEN
Chinese Journal of Pathophysiology 1986;0(01):-
AIM: To observe the oxidative modification of low density lipoprotein iinduced by hyper homocysteinaemia following application of methionine. METHODS: Thirty two rabbits were randomized as group methionine(group M, n =9), group cholesterol (group Ch, n= 9), group methionin+cholesterol (group M+Ch, n= 9) and control group (group C, n= 5).In group M, Ch and M+Ch, the animals were fed with the food containing 3% methionine, 3.75% cholesterol and 3% methionine+3.75% cholesterol, respectively. By the end of sixteen weeks, the blood were taken and the measurements were carried out. RESULTS: Following application of methionine, the levels of hyperhomocysteine, ox-LDL and TBARS in group M and group M+Ch were significntly higher than those of group C and group Ch ( P
5.Strategy for treatment of subtrochanteric femur fractures in children and adolescents
Liaojun SUN ; Hua CHEN ; Xiaoshan GUO ; Jun PAN
Chinese Journal of Trauma 2009;25(12):1068-1071
Objective To evaluate the treatment methods for subtrochanteric femur fractures in children and adolescents.Methods Sixty-two patients (at age of 4-16 years) with subtrochanteric fe-mur fractures were managed with traction and delayed hip spica (14 patients, set as nonoperative group) ,titanium elastic nails or pin combined with cast (38 patients, set as less invasive group) and plates (10 patients, set as traditional operative group).The radiologic outcomes, hip joint function and complica-tions of the patients were analyzed.Results According to Beaty scoring, five patients in nonoperative group and 44 in operative group obtained satisfactory early radiologic outcomes.Late radiologic outcome was satisfactory in nine patients from nonoperative group and 46 from operative group according to Theolo-gis scoring, with statistical differences between two groups (P<0.05).Sanders scoring showed excellent results in 11 patients and good in three from nonoperative group, and excellent results in 43 and good in five from operative group, with no statistical differences between two groups (P > 0.05).Less invasive group and traditional operative group showed significantly statistical different in aspects of complications and Sanders scores (P < 0.05).Conclusions Operative treatment provides more satisfactory early and late radiologic results than nonoperative methods.Less invasive operations have better outcomes than tra-ditional operative methods.Selection of treatment modalities based on age, body weight, fracture features and soft tissue conditions of children is the prerequisite for a good outcome.
6.Minimally invasive plate osteosynthesis and humeral head replacement for treatment of elderly patients with Neer four-part fractures
Liaojun SUN ; Gao HUANG ; Xiaoshan GUO ; Xianbin YU ; Wei HU ; Hua CHEN
Chinese Journal of Trauma 2012;28(5):412-417
ObjectiveTo identify the curative effect of minimally invasive plate osteosynthesis (MIPO) and humeral head replacement in treatment of elderly patients with Neer four-part fractures.MethodsUsing the deltoid pectoral approach,28 patients with fresh Neer four-part fractures were treated by the locking plate combined with MIPO (Group A) and 27 by the humeral head replacement (Group B).Neer score,Constant-Murley score and simple shoulder test (SST) questionnaire were adopted for assessing the treatment outcome.ResultsGroup A was followed up for mean 32.1 months,which showed screws protruding into the joint space in two patients,tuberosity upward and backward displacement in one and femoral head ischemic necrosis in one.The mean visual analog scale (VAS) score,the mean Neer score and the mean Constant-Murley score were 2.2 points,88.6 points and 86.5 points respectively.There were average 9.0 answers for “yes” in the SST questionnaire.Group B were followed up for mean 34.6 months,which showed shoulder dislocation or subluxation in four patients,tuberosity displacement or excessive reduction in eight.The mean VAS score,the mean Neer score and the mean Constant-Murley score were 2.4 points,78.9 points and 77.3 points respectively.The mean number of answer for “yes” in SST questionnaire was 8.0 questions.There showed no statistical difference in VAS score between the two groups.While statistical difference was found in complications,Neer score,Constant-Murley score and SST score between two groups,with Group A superior to Group B.Conclusions For most elderly patients with Neer four-part fractures,MIPO has satisfactory results under strict control of surgical indications and technical tips.The humeral head replacement surgery still has many unresolved problems and needs careful consideration.
7.A modified posterolateral approach for lateral and posterior malleolar fractures: a preliminary report
Wenlai FANG ; Mochuan CHEN ; Liaojun SUN ; Jianzhong KONG
Chinese Journal of Orthopaedic Trauma 2020;22(1):45-48
Objective To observe the clinical efficacy of internal fixation through a modified posterolateral approach in the treatment of lateral and posterior malleolar fractures.Methods From January 2015 to January 2018,25 patients with fracture involving the lateral and posterior malleolus were treated at Department of Orthopedics,The Second Affiliated Hospital to Wenzhou Medical University.They were 13 males and 12 females,aged from 18 to 70 years (mean,43.1 years).By the Lauge-Hansen classification for ankle injury,9 cases belonged to supination-supination type of degree Ⅲ,11 to supination-supination type of degree Ⅳ,and 5 to pronation-supination type of degree Ⅳ.By the Haraguchi classification,all the posterior malleolar fractures in this series belonged to type Ⅰ.Internal fixation through a modified posterolateral approach was performed for all the lateral and posterior malleolar fractures.Their operation time,fracture healing time and postoperative complications were observed.At the last follow-up,ankle joint function was assessed by the American Orthopedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale.Results In the 25 patients,the operation time ranged from 50 to 100 min (mean,70 min).Of this group,21 patients were followed up for 12 to 18 months (mean,14 months).Bony union was achieved after 3 to 5 months after operation.Superficial wound infection was observed in 3 cases.No such complications occurred like postoperative adhesion,deep infection,contracture of flexor hallucis longus tendon,or loosening or breakage of implants.By the AOFAS ankle-hindfoot scale at the last follow-up,the ankle function was excellent in 13 cases,good in 6 and fair in 2.Conclusion The modified posterolateral approach is worth popularizing in clinic because it provides possibilities of fixating the lateral and posterior malleolar fractures by the same incision,not stripping the muscular origins of the flexor hallucis longus and reducing postoperative adhesion of the flexor hallucis longus.