The incidence of iatrogenic bile duct injuries has been increased along with the application of laparoscopic surgery, although surgical lesions have been reduced and postoperative recovery has been accelerated. Once bile duct injury occurs, the short-term and long-term adverse effects are very severe. Therefore, the prevention and timely diagnosis and treatment of bile duct injuries are critical. In order to better understanding iatrogenic bile duct injuries and guiding the clinical practices for young surgeons, this paper provides the updated information on common causes, mechanisms, diagnosis, and treatment of iatrogenic bile duct injuries through review of domestic and international literature.