Objective: To investigate the current status of job burnout in in-service sailors, and to provide a basis for the development of intervention measures for job burnout in sailors. Methods: From September 2015 to May 2016, stratified cluster random sampling was used to select 6 172 in-service sailors from 13 provinces and cities as research subjects. General demographic data including age, education background, and household registration and occupational characteristics such as job position, navigating zone, and nature of employment were collected. The Maslach Burnout Inventory-General Survey (MBI-GS) was used to measure the levels of emotional exhaustion, depersonalization, low occupational efficiency, and job burnout, and the influencing factors for job burnout were also analyzed. Results: Of all 6 172 in-service sailors, 112 (1.8%) had a positive result in emotional exhaustion, 870 (14.1%) had a positive result in depersonalization, and 3 517 (57.0%) had a positive result in low occupational efficiency. Of all sailors, 63.3% had job burnout, among whom 54.1% had mild burnout, 8.7% had moderate burnout, and 0.5% had severe burnout. There was a significant difference in the score of job burnout between the sailors with different ages, education backgrounds, types of household registration, job positions, navigating zones, ornature of employment (P<0.05). Age, education background, household registration, job position, navigating zone, and nature of employment were major influencing factors for job burnout in in-service sailors (P<0.05) , and there was a higher level of job burnout in the sailors with an age of 30-39 years, education background of junior college or above, urban registration, a job position of second mate/third engineer, a navigating zone of coastal lines, orthe nature of employment of freelance sailor. Conclusion There is a high incidence rate of job burnout among in-service sailors, and the sailors with a young age, urban registration, a navigating zone of coastal lines, or thenature of employment of freelance sailor tend to have low occupational efficiency. Related measures should be adopted for active intervention.

Objective To study the relationship between seven antibody of lung cancer and the chemotherapy effect and prognosis of patients with non-small cell lung cancer(NSCLC).Methods A total of 42 patients with NSCLC admitted to Taihe County People's Hospital from June 2022 to December 2023 were selected.All subjects underwent 4 cycles of chemotherapy.They were divided into effective group(n=25)and non-effective group(n=17)according to the outcome of chemotherapy.The seven antibody of lung cancer were titrated and compared and the efficacy in evaluating chemotherapy was analyzed by receiver operating characteristic(ROC)curve.In addition,the subjects were divided into a good prognosis group(n=21)and a poor prognosis group(n=21)according to the difference in clinical outcomes.The seven antibody of lung cancer were titrated and compared between the two groups,and the relationship between the antibody level and the prognosis of NSCLC patients was determined by multivariate Logistic regression analysis.Results The an-tibody level in effective group was lower than that in the non-effective group(P＜0.05).ROC curve analysis confirmed that the level of CAGE,GAGE7,GBU4-5,P53,PGP95,SOX2 and MAGEA1 is significantly re-lated to better efficacy of chemotherapy and the areas under the curve were 0.861,0.769,0.778,0.786,0.793,0.842 and 0.833,respectively.The antibody level of lung cancer in poor prognosis group was higher than those in good prognosis group(P＜0.05).Multiple Logistic regression analysis confirmed that the seven antibody levels were the risk factors for poor prognosis in NSCLC patients(all OR value＞1,P＜0.05).Conclusions The level of seven antibody of lung cancer are negatively related to the chemotherapy effect and prognosis of NSCLC patients.With increase of the seven antibody level of lung cancer,prognosis of patients re-sulted from chemotherapy is worse.

OBJECTIVE: To develop a mental health self-assessment scale for Chinese seafarers. METHODS: The detail dimensions and clauses of Mental health scale for Chinese seafarers( MHSCS) was composed through literature reviews,interviews and expert evaluation. A total of 1309 seafarers were randomly recruited as test subjects by convenience sampling method, and the preliminary scale was constructed to predict their mental health. The formal scale was established after data analysis by analyzing means of differentiation,correlation,exploratory factor and frequency,then its reliability and validity were tested. RESULTS: The MHSCS contains 109 entries in 11 dimensions. Its Cronbach 's αcoefficient of the total scale and each dimension was 0. 638-0. 982,and the retest reliability was 0. 806-0. 922. The scores in each dimension of the scale were positively correlated with the scores of each dimension of Symptom Checklist 90 scores( correlation coefficient = 0. 486-0. 860,P < 0. 01). The confirmatory factor analysis showed that the model fitted well(x~2/df = 2. 93,the normed fit index was 0. 950,the non-normed fit index was 0. 970,the incremental fit index was 0. 970,the relative fit index was 0. 950,the comparative fit index was 0. 970,the root mean square error of approximation was 0. 067). CONCLUSION: The MHSCS has good reliability and validity,meets the requirements of psychometrics standard,and can be used as a mental health evaluation tool for the Chinese seafarers.