1.Effect of non-accompany nursing on mood of caesarean section maternal
Xiangying NG ZHA ; Lianqing GONG ; Xiaoling DING ; Caimei YE
China Modern Doctor 2014;(30):73-75
Objective To investigate the effect of non-accompany nursing on mood of caesarean section maternal. Methods A total of 320 caesarean section maternal were selected and divided into the observation group and the con-trol group with each group 160 cases. The both groups were given routine nursing. But the daily life nursing in the control group was performed by family members, the daily life nursing in the observation group was performed by hos-pital escort. The self-rating anxiety scale(SAS), salf-rating depression scale(SDS) were and satisfaction at 1 d before surgery and 6 d after surgery in two groups were recorded and compared. Results The SAS scores in two group at 1d before surgery were similiar. The difference was not statistically significant(P>0.05). But the SAS score of the observa-tion group(45.98±1.94) were lower than that of the control group(49.15±2.88), the difference was statistically signifi-cant(P<0.05). The SDS scores in two group at 1 d before surgery were similiar. The difference was not statistically significant(P>0.05). But the SDS score of the observation group(46.15±2.25)were lower than that of the control group(51.74±3.09), the difference was statistically significant(P<0.05). The satisfaction of the observation group was better than that of the control group. The difference was statistically significant(P<0.05). Conclusion Implementing the non-accompany nursing can effectively improve reduce the anxiety and depression of caesarean section maternal, contribute to improve the quality of rehabilitation.
2. Advances in immunotherapy of extranodal NK/T cell lymphoma
Dingqian HAO ; Lianqing LI ; Maocai LI ; Lili GONG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2019;54(12):949-953
Extranodal NK/T-cell lymphoma (ENKTCL) is a relatively rare group of highly aggressive non-Hodgkin′s lymphoma (NHL). The disease has rapid clinical progress, high degree of malignancy and poor prognosis. Traditional chemoradiotherapy regimens have not shown good efficacy. In recent years, the immunotherapy of tumors has developed rapidly. At present, it has shown strong therapeutic activity in the treatment of various solid tumors such as non-small cell lung cancer, prostate cancer, melanoma and kidney cancer. Multiple tumor immunotherapy drugs have been approved by the US Food and Drug Administration (FDA) for clinical use. This article reviews recent novel immunotherapeutic regimens of ENKTCL, hoping to change the treatment modality of this malignant disease.
3.Hippocampal subfield volume alteration in post-traumatic stress disorder: a magnetic resonance imaging study.
Lu LU ; Lianqing ZHANG ; Xinyu HU ; Xiaoxiao HU ; Lingjiang LI ; Qiyong GONG ; Xiaoqi HUANG
Journal of Biomedical Engineering 2018;35(2):252-257
In the current study, we aim to investigate whether post-traumatic stress disorder (PTSD) is associated with structural alterations in specific subfields of hippocampus comparing with trauma-exposed control (TC) in a relatively large sample. We included 67 PTSD patients who were diagnosed under Diagnostic and Statistical Manual of Mental Disorders (4th Edition) (DSM-Ⅳ) criteria and 78 age- and sex-matched non-PTSD adult survivors who experienced similar stressors. High resolution T1 weighted images were obtained via a GE 3.0 T scanner. The structural data was automatically segmented using FreeSurfer software, and volume of whole hippocampus and subfield including CA1, CA2-3, CA4-DG, fimbria, presubiculum, subiculum and fissure were extracted. Volume differences between the two groups were statistically compared with age, years of education, duration from the events and intracranial volume (ICV) as covariates. Hemisphere, sex and diagnosis were entered as fixed factors. Relationship between morphometric measurements with Clinician-Administered PTSD Scale (CAPS) score and illness duration were performed using Pearson's correlation with SPSS. Comparing to TC, PTSD patients showed no statistically significant alteration in volumes of the whole hippocampus and all the subfields ( > 0.05). In male patients, there were significant correlations between CAPS score and volume of right CA2-3 ( = 0.197, = 0.034), right subiculum ( = 0.245, = 0.016), and duration statistically correlated with right fissure ( = 0.247, = 0.016). In female patients, CAPS scores significant correlated with volume of left presubiculum ( = 0.095, = 0.042), left subiculum ( = 0.090, = 0.048), and left CA4-DG ( = 0.099, = 0.037). The main findings of the current study suggest that stress event causes non-selective damage to hippocampus in both PTSD patients and TC, and gender-specific lateralization may underlie PTSD pathology.