Nursing experience in the therapy of 45 cases of Rh blood group incompatibility was reported,and the nursing requirements were raised as follows:(1)good nurse patients relationship is important and psychological nursing should be done well.(2)Teach the patient to insist of systematic treatment,master timely intrauterine state of fetus.(3)Observe progressions and regression of jaundice,and general statement of newborn.(4)Enhance newborn nursing in the phototherapy.(5)Observe newborns physical signs in the course of blood exchange,predict the occurrence of complications.Results:one case was labor induced sine fetal death,40 cases lived without complications,4 cases died,the cure rate reached 88.9 percent.Conclusion:Though Rh blood group incompatibility is severe,most of them can be cured through timely treatment and careful nursing.

Objective To compare the initial detection rate and the accuracy of qualitative diagnosis of multislice spiral computed tomography (MSCT),gastrointestinal tract radiography,gastroscopy,and endoscopic ultrasonography in the diagnosis of gastric lipoma,with a focus on evaluating the diagnostic value of MSCT.Methods Twenty-six patients with gastric lipoma,6 males and 20 females with a mean age of 61 years (ranging from 41 to 82 years) and confirmed by pathology,were enrolled in the present study.Their clinical,pathologic and imaging findings were retrospectively analyzed.All the patients underwent gastroscopy,and plain and dynamic enhanced MDCT scans.Of them 21 cases underwent endoscopic ultrasonography and 12 cases gastrointestinal tract radiography.Results The detection rate was 88.5％(23/26) and 80.8％(21/26),P＞0.05 for MSCT and gastroscopy,respectively,in the initial diagnosis of gastric lipomas,both higher than that of gastrointestinal tract radiography (41.7％,5/12).The accuracy of qualitative diagnosis of MSCT (100％,23/23) was higher than that of endoscopic ultrasonography (71.4％,15/21),gastrointestinal tract radiography (0％,0/5) and gastroscopy (0％,0/21).The lesions located at the gastric antrum in 18 cases (69.2％,including 10 front wall,6 posterior wall and 2 pyloric canal),the gastric body in 7 cases (26.9％) and the gastric fundus in 1 case (3.8％).All the lipomas presented as round or ovoid nodule with clear boundary on MSCT images,and homogeneous or mixed low density.The CT values,long dimensions and volumes ranged from-50 to-95Hu (mean-72.58Hu),5.7 to 40.7mm (mean 17.67mm) and 0.02 to 7.03cm3 (mean 1.89cm3),respectively.Contrast-enhanced CT scans showed no enhancement in all the lesions.Conclusion MSCT can make accurate locating and qualitative diagnosis for gastric lipomas.

Objective To evaluate the effect of limb remote ischaemic preconditioning on pul-monary function in patients undergoing cardiac valve replacement surgery with cardiopulmonary by-pass.Methods Seventy patients,32 males and 38 females,aged 18-70 years,weighing 45-90 kg, ASA physical status Ⅱ or Ⅲ,scheduled for elective cardiac valve replacement surgery with cardiopul-monary bypass,were divided into 2 groups using a random number table,35 in each group.Patients in group R received three cycles of right upper-limb 5 min ischemia (blood-pressure cuff inflation to≥ 200 mm Hg)and 5 min reperfusion (blood-pressure cuff deflation to 0 mm Hg)at 10 min after in-tubation.In group C,the cuff was placed around the arm but not inflated.At 10 min after intubation (T0),at 1 h after aortic declamping (T1)and at 6 h (T2),12 h (T3),24 h (T4)after surgery,arte-rial blood was sampled to conduct gas analysis,PaO2/FiO2ratio and alveolar-arterial oxygen gradient (A-aDO2)were calculated,and the dynamic lung compliance (Cd)and static lung compliance (Cs) were also recorded.The occurrence of pulmonary adverse events was recorded until discharge. Results Compared with T0,PaO2/FiO2was decreased in the two groups at T1-T4,A-aDO2was de-creased at T2-T4,Cs and Cd were increased in group C at T3,and were increased in group R at T2, T3(P<0.05).Compared with group C,the Cs and Cd at T2,T3were increased in group R.There were no significant differences between the two groups in the PaO2/FiO2,A-aDO2at T0-T4.The oc-currence of the pulmonary adverse events was decreased significantly in group R than in group C (P<0.05).The occurrence of pulmonary adverse events was declined significantly in group R than in group C (P<0.05).Conclusion Limb remote ischemic preconditioning can improve the lung compli-ance and reduce the occurrence of the pulmonary adverse events in patients undergoing cardiac valve replacement surgery.

Objective To explore the therapeutic effect of lignans extracted from Eucommia Ulmoides Oliver on diabetes encephalopathy(DE)rats and the effects on nuclear factor E2 related factor 2(Nrf2)/heme oxygenase-1(HO-1)signaling pathway.Methods A rat model of DE was established,and 48 successfully established DE rats were randomly divided into model group,and low-and high-dose lignans groups(200 and 400 mg/kg),and metformin(200 mg/kg)group,with 12 rats in each group.Another 12 healthy rats served as control group.Each group of rats was giv-en corresponding drug intervention once a day for 6 consecutive weeks.Cognitive and memory abilities,serum levels of IL-6,TNF-α,MDA and SOD,and mRNA and protein levels of Nrf2 and HO-1 in the hippocampus were measured in all groups.Pathological changes of the hippocampus were observed after HE staining.Results Compared with the control group,significantly longer escape latency and increased serum levels of IL-6,TNF-α and MDA,while lower times of crossing original platform,shorter residence duration of original platform quadrant,decreased serum SOD level,and reduced mRNA and protein levels of Nrf2 and HO-1 in the hippocampus were observed in the model group(all P＜0.05).Low-and high-dose lignans treatment reversed all above indica-tors when compared with model group(P＜0.05).What's more,the effects of high-dose lignans treatment were more significant than low-dose treatment in escape latency,serum levels of IL-6,TNF-α and MDA,times through the original platform,residence duration of the original platform quadrant,serum SOD level,and mRNA Nrf2 and HO-1 in the hippocampus(6.07±0.70 vs 4.76± 0.52,30.96±2.96 s vs 23.49±2.60 s,77.02±6.51 U/ml vs 61.71±6.75 U/ml,0.69±0.06 vs 0.49± 0.05,0.74±0.07 vs 0.57±0.06,P＜0.05).Conclusion Eucommia lignans can improve the cogni-tive ability,enhance the antioxidant capacity,inhibit inflammatory response and protect the hippo-campus of DE rats,and the mechanism may be related to the activation of Nrf2/HO-1 signaling pathway.

Objective To study the nursing effect of temporary ballon occlusion of the abdominal aorta in the treatment of pernicious placenta previa and placenta accrete. Methods Nursing points and experience of 126 cases of pernicious placenta previa and placenta accreta using temporary ballon occlusion of the abdominal aorta to prevent intraoperative bleeding in caesarean section were retrospectively summarized. This paper introduced the method, safety and superiority of the way of temporary ballon occlusion of the abdominal aorta, and the method of nursing care of patients with temporary ballon occlusion of the abdominal aorta, and the methods of the observation and prevention of postoperative bleeding and the nursing of pain. Results Totally 126 patients successfully achieved hemostasis, no hysterectomy occurred. Conclusions Through effective nursing of temporary ballon occlusion of the abdominal aorta in the treatment of pernicious placenta previa and placenta accrete, the postpartum hemorrhage, blood transfusion and the risk of hysterectomy can be reduced.

Objective To investigate the application effects of information primary care quality control in obstetric ward so as to improve the nursing quality and provide better service.Methods The content of the information nursing quality control was revised by nursing department. Management measures of information primary care quality control were established and implemented.Results Through practice, the rate of nursing quality indexes, satisfaction rate of nursing service and satisfaction rate of nurses to quality control of nursing were improved (P<0.05).Conclusions The establishment of information primary care quality control system ensures the real-time and objectivity of nursing quality control and improves satisfaction and enthusiasm of nurses, thus effectively improves nursing quality and satisfaction of patients.

Objective We previously demonstrated that peroxiredoxin 3 (PRX3) was overexpressed in cervical cancer and the expression of PRX3 was positively associated to that of oncogenes E6/E7 of human papillomaviruses (HPV) type 16.The present study was conducted to investigate the link between HPV oncogenes and PRX3,which would be helpful to understanding the mechanism for cervical carcinogenesis.Methods Cervical epithelial cells were cultured and were transfected with recombinant pcDNA3.1 vector containing HPV16 E6/E7.The changes of PRX3 expression were detected by quantitative real time PCR and Western blotting.Results In the epithelial cells which stably expressed HPV16 E6/E7,the expression of PRX3 was significantly down-regulated at both mRNA and protein levels compared to that in the control cells.Conclusion Integration of high risk HPV DNA into the chromosomes of cervical epitheliums induced the change of the PRX3 expression,which might be involved in the initiation of cervical cancer.

Objective:To explore the current status of post-traumatic stress disorder (PTSD) and family resilience in high-risk pregnant women, and analyze the correlation between them.Methods:From March to December 2019, convenience sampling was used to select 400 high-risk pregnant women from a ClassⅢ Grade A hospital in Zhengzhou as the research object. The General Information Questionnaire, PTSD Checklist-Civilian Version (PCL-C) and Family Resilience Questionnaire were used to investigation when pregnant women went to the Obstetric Clinic for review to analyze the relationship between PTSD and family resilience of delivery women. A total of 400 questionnaires were issued, and 378 valid questionnaires were returned with the effective response rate of 94.5%.Results:The total PCL-C score of 378 pregnant women with high-risk pregnancy was (31.53±7.54) and the total family resilience score was (76.85±12.74) . The level of PTSD was negatively correlated with family resilience with a statistical difference ( r=-0.287, P=0.003) . The results of hierarchical regression analysis showed that the firmness and support of family resilience could explain 38.3% of the total variability of PTSD in high-risk pregnancy women. Conclusions:Family resilience of high-risk pregnant women has a negative predictive effect on PTSD. Medical and nursing staff should reduce the level of PTSD in high-risk pregnant women from the perspective of family resilience.

Objective:To explore the influence of the "4C" continuous nursing model on the quality of life and breastfeeding self-efficacy of puerperium women.Methods:A total of 136 puerperium women in a tertiary hospital from February to December 2019 were selected as the research objects by convenience sampling method. According to the random number table, they were randomly divided into the control group and the intervention group, with 68 cases in each group. Conventional nursing methods were applied in the control group, while "4C" continuous nursing model was applied on the basis of the control group in the intervention group. The MOS 36-Item Short Form Health Survey (SF-36) and the Breastfeeding Self-Efficacy Scale were applied to compare the quality of life and breastfeeding self-efficacy between the two groups before and after the intervention. In this study, a total of 136 questionnaires were issued and 126 valid questionnaires were returned. The effective response rate was 92.65%.Results:The scores of SF-36 and Breastfeeding Self-Efficacy Scale of the intervention group were higher than those of the control group, and the differences were statistically significant ( P<0.05) . Conclusions:The "4C" continuous nursing model can improve the quality of life of puerperium women and improve the self-efficacy of breastfeeding.

Objective To explore the types of variations in the origin of left gastric artery (LGA) using MSCT angiography.Methods The abdominal MSCT angiography data of 1 500 patients were respectively reviewed,in thoses the abdominal aorta,celiac trunk,LGA,common hepatic artery (CHA),splenic artery (SA) and superior mesenteric artery (SMA)were shown clearly.The origins of the LGA and related artries were focused.A new typing method (types Ⅰ-Ⅹ) was established.And the incidence of various types was calculated.Results The normal anatomical origin (type Ⅰ) of LGAwas noted in 1 342 cases (1 342/1 500,89.47％).Eight types of LGA variant origin were identified in 70 cases (70/1 500,4.67％).LGA variant origin combined with celiomesenteric trunk (CMT) were observed in 47 cases (47/1 500,3.13％).The most common type of LGA origin variation was LGA originated from the abdominal aorta combined with CMT (type Ⅴ) which was found in 24 cases (24/1 500,1.60％).And the least common type was the namely LGA,SA,CHA and SMA arose independently from abdominal aorta (type Ⅵ) which was found in 3 cases (3/1 500,0.20 ％).LGA originated from SMA (type Ⅷ) was not found in all 1 500 cases.Conclusion There are many kinds of variations in the origin of LGA.The new typing method can contribute the comprehensive and intensive data for understanding the anatomical and radiographic features.