AIM: To establish a method for the determination of trace amounts arsenic in Pule'an Tablet (Chinese Cabbage Pollen). METHODS: Hydride generation atomic absorption spectrometry was used to determine arsenic by microwave digesting sample. RESULTS: The detection limit of the method was 0.045 ?g/Kg, RSD= 5.9%, the recovery was in the range of 90%～106%. CONCLUSION: The method is simple,rapid and with high sensitivity, and can be applied for the determination of trace amounts arsenic in Pule'an Tablet.

Objective Using IPA rate to assess platelet reactivity of coronary heart disease patients re-ceived the dual antiplatelet therapy after PCI. Methods CHD patients received the loading dose of clopidogrel (300 mg)on the first day of hospitalization or before PCI,then received clopidogrel(75 mg/d)and aspirin(100 mg/d) for one year. IPA was measured after administration of the loading dose of clopidogrel. The patients were divided into the HPR and LPR group according to the rate of IPA. Observe patients incidences of cardiovascular events were followed up for one year. Results A total of 102 patients were enrolled into this study ,including 77 males and 25 females with average age of 65.7 ± 10.9. Patients were divided into the HPR and LPR group with 69 and 33 patients,respectively. The average IPA value of HPR group was obvious lower than that of LPR group(P<0.01). The accumulative 12-month cardiovascular events incidence in the HPR and LPR group were 15.9% and 3.0% respectively ,with significant difference (P < 0.05). Conclusion IPA could be used to evaluate platelet reactivity,which suggests that clinicians can detect IPA to reduce or avoid the recurrence of cardiovascular events.

OBJECTIVE: To retrospectively analysis the clinical data of facial nerve defects repair with greater auricular nerve graft. METHOD: The transmastoid approach was adopted to repair the facial nerve defects by means of nerve grafting. Preoperative and postoperative facial nerve functions were graded according to the House-Brackmann scale. RESULT: The patterns of temporal bone fracture in the 8 patients were longitudinal, most lesions occurred in the region of the second genu and its surrounding, preoperatively, all patients had Grade VI function. In 3 patients of facial nerve tumors, the tumors involved multiple nerve segments, and histologic results were all schwannomas, preoperatively, 1 case had Grade III function, 2 cases had Grade V function. In 2 patients of iatrogenic trauma of the facial nerve, the primary disease was chronic otitis media with cholesteatoma, the lesions were localized at the mastoid segment and the second genu respectively. In 1 patient of molten steel burn, the lesions was localized at the tympanic segment, preoperative facial nerve function was Grade VI. In addition to 3 cases lost to follow-up, the remaining patients, 4 recovered to a Grade III, 3 to a Grade VI, 2 to a Grade V and 2 remained at Grade VI. CONCLUSION In present study, the most common cause of facial nerve transection was temporal bone fracture. Facial nerve reconstruction by means of greater auricular nerve grafting was a practical and effective method, the best postoperative recovery of facial nerve function was Grade III.
Adult ; Cranial Nerves ; transplantation ; Ear ; innervation ; Facial Nerve Injuries ; surgery ; Facial Paralysis ; surgery ; Female ; Humans ; Male ; Mastoid ; surgery ; Middle Aged ; Nerve Regeneration ; Neurosurgical Procedures ; methods ; Retrospective Studies ; Temporal Bone ; injuries ; surgery ; Young Adult

Objective:To investigate the preoperative ascending aorta diameter in patients with acute type A aortic dissection in the Chinese population, compares and analyze the differences in preoperative blood biomarkers, and evaluate the impact of the preoperative ascending aorta diameter in this part of patients on the short-term prognosis of patients.Methods:A collection of 641 patients with acute type A aortic dissection who were enrolled in the " Acute Aortic Syndrome High-Risk Early Warning and Intervention Study" project from January 2018 to January 2020 were collected. Divide the patients into two groups (group Ⅰ<55 mm, group Ⅱ≥55 mm) according to the preventive intervention value of ascending aorta diameter recommended by the guideline for studying preoperative ascending aorta diameter difference in blood biomarkers and the influence of ascending aorta diameter on the short-term prognosis of patients. All patients had CT scans to assess the diameter of the ascending aorta before operation.Results:In this study, all patients with acute type A aortic dissection had a mean preoperative ascending aorta diameter of (46.9±9.7)mm. The preoperative ascending aorta diameter of all patients was less than 55 mm, accounted for 84.1%. Male patients were more likely to have aortic dissection than females; most patients' age was less than 60 years old. The preoperative blood inflammatory index counts were higher in the ascending aorta diameter ≥55 mm group. However, the long-term prognosis of patients with different ascending aorta diameters before surgery was not apparent in this study. The preoperative survival rate and short-term survival rate of patients with ascending aorta diameter <55 mm were higher than those of other groups, but the difference was not statistically significant.Conclusion:In patients with acute type A aortic dissection, the diameter of the ascending aorta is usually less than 55 mm. Moreover, the blood inflammatory index counts are high in the preoperative ascending aorta diameter ≥55 mm group. Meanwhile, patients with smaller ascending aorta diameter have better survival rate and short-term prognosis.

Adrenal Cortex Hormones ; Antibodies, Monoclonal, Murine-Derived ; Humans ; Rituximab ; Thrombocytopenia ; gamma-Globulins