1.A Retrospective Analysis of 105 Drowning Victims with Psychiatric Disorders
Hai ZHAO ; Limin DONG ; Lianjie SUN ; Deyuan DENG ; Meng HE
Journal of Forensic Medicine 2014;(6):456-459
Objective To analyze the features of drowning victim s with psychiatric disorders to support further investigation on such cases. Methods O ne hundred and five archives of drowning victim s with psychiatric disorders from January 2010 to June 2014 in H arbor Public Security Subbureau, Shanghai Public Security B ureau were reviewed. The decedents’ general inform ation, autopsy findings, case inves-tigation data and disease histories were statistically analyzed. Results O f the 105 cases, 104 were sui-cides. Most decedents were poorly educated. Most suicides occurred in warm clim ate, and the corpses were usually found within 2 days. Most decedents had no suicide history and notes, but had abnorm al m ental or behavior changes before suicide. D epression, depression status and schizophrenia were the m ain types of psychiatric disorders, and only 9 decedents had received regular therapies before their deaths. Conclusion Mental disorder is a high risk factor in the drowning victim s. G uardians should be aware of psychotic abnorm al behaviors, especially during warm clim ate seasons.
2.Application of rapid rehabilitation nursing in perioperative nursing of patients with laparoscopic hiatal hernia
Yao SUN ; Yong ZHAO ; Qianqian TAN ; Lianjie ZHANG
Chinese Journal of Modern Nursing 2017;23(3):404-408
Objective To explore the clinical effect of rapid rehabilitation in the perioperative nursing of patients who received total laparoscopic hiatal hernia repair and analyze specific methods and practice. Methods Totally 236 patients who received total laparoscopic hiatal hernia repair between June 2012 and June 2016 were selected by purposive sampling method and were divided into the control group and the intervention group by using the random function method,with 118 patients in each group. Patients in the control group received routine nursing,while patients in the intervention group received nursing based on the concept of rapid rehabilitation,namely,health education related to diseases and operations before operation, reduction of in-dwelling urethral catheter,temperature and humidity control,infusion warming,warmth retention of human body and infusion volume control during operation as well as early ambulation,early removing of stomach tubes, preventive use of thrombus therapeutic instrument and other nursing measures for rapid rehabilitation after operation. The differences in time of early ambulation,time of anal exhaust,time of first feeding, postoperative morbidity,hospitalization time and hospitalization expenses between two groups were compared.Results The proportion of ambulation within 24 hours after surgery in the intervention group was 93.22%,which was higher than that in the control group (40.68%) (χ2=73.611,P<0.01);the time of removing stomach tubes,anal exhaust and first feeding were [(19.5±4.70),(21.9±2.2),(23.6±3.1)] hours in the intervention group,and they wereshorter than those in the control group [(26.8±3.6),(26.5±1.8),(28.9±4.3)] hours (t=13.394,17.579,10.861;P<0.01);the incidence rate of postoperative complications in the intervention group was 2.54%,which was lower than that in the control group (18.64%) (χ2=16.151,P<0.05);in the intervention group,the postoperative hospitalization time and expenses were (5.6±2.1) days and (28772.9±1890.1) yuan,and they were lower than those in the control group [(7.8±1.8) days,(30011.7±2113.4) yuan] (t=8.640,4.746;P<0.01).Conclusions The application of rapid rehabilitation in the perioperative nursing of patients with hiatal hernia repair enables patients to ambulate earlier,reduce the incidence of postoperative complications and accelerate the recovery of intestinal functions after operation.
3.The effects of dynamic instability training on the postural control, balance and walking of stroke survivors
Lianjie MA ; Xudong GU ; Yan LI ; Jianming FU ; Yunhai YAO ; Linhua TAO ; Liang LI ; Ya SUN ; Hua WU
Chinese Journal of Physical Medicine and Rehabilitation 2023;45(3):210-215
Objective:To observe any effect of dynamic motor instability training on the balance and postural control of stroke survivors.Methods:Forty stroke survivors with poor balance were randomly divided into a control group and an observation group, each of 20. In addition to routine rehabilitation, the observation group was given 20 minutes of dynamic motor instability training, 5 days a week for 8 weeks, while the control group underwent routine rehabilitation for the same length of time. Before and after the intervention, surface electromyogram of the rectus femoris, biceps femoris, and erector spinae were recorded during perturbation. Activation time and the intensity of the anticipatory and complementary postural adjustments (APAs and CPAs) were also observed. Balance and lower limb motor functioning were assessed using the Berg balance scale (BBS), the Fugl-Meyer lower extremity assessment (FMA-LE), and GaitWatch analysis.Results:After the treatment the average activation time of the rectus femoris, biceps femoris in the affected side and those of the biceps femoris [(-84.31±5.74)s] and erector spinae in the intact side in APAs were all significantly shorter in the observation group than in the control group, while the average activation intensity of the rectus femoris and erector spinae was significantly greater. There was no significant difference in the activation intensity of each muscle group in CPAs after the treatment. After the intervention the average BBS score, FMA-LE score, stride length and walking speed of the observation group all were significantly better than the control group′s averages.Conclusions:Supplementing traditional rehabilitation training with dynamic motor instability training can further improve the posture control of stroke survivors and promote recovery of their balance and walking ability.
4.Establishment of a preoperative prediction model for axillary lymph node burden in patients with early breast cancer
Xianfu SUN ; Qiang ZHANG ; Lianjie NIU ; Tao HUANG
Chinese Journal of Oncology 2021;43(5):563-568
Objective:To explore the method of predicting high lymph node load in patients with early breast cancer to avoid unnecessary sentinel lymph node biopsy.Methods:The clinicopathological and thoracic multi-slice spiral CT (MSCT) data of 2620 patients with early (cT1~2N0M0) breast cancer treated in the Affiliated Cancer Hospital of Zhengzhou University from January 1, 2014 to August 1, 2018 were collected. According to the postoperative pathological results, the patients were divided into the group with axillaryhigh lymph node burden (HNB) and the non-HNB group. The influencing factors of axillary lymph node burden in patients with early breast cancer were determined by univariate and multivariate analysis, and the diagnostic model of MSCT to HNB was established. The best cutoff value for the diagnosis of HNB was determined through analyzing the receiver operative characteristic (ROC) curve, and the consistency between MSCT diagnosis and pathological diagnosis was evaluated by Kappa test. Results:Among the 2 620 patients, 168 were diagnosed of HNB. Univariate analysis showed that the tumor size, the status of human epidermal growth factor receptor 2 (HER-2), the number of abnormal lymph nodes showed in MSCT, the ratio of the length to the diameter of the maximum abnormal lymph node as shown in MSCT, the condition of the maximum abnormal lymph node door, and the parenchyma of the maximum abnormal lymph node were related to axillary lymph node burden in patients with early breast cancer ( P<0.05). Multivariate analysis showed that the number of abnormal lymph nodes showed in MSCT was an independent influencing factor of axillary HNB in patients with early breast cancer. Compared with patients without abnormal lymph nodes, the OR values of patients with 1, 2, 3 or more abnormal lymph nodes displayed by MSCT and in axillary HNB status were 3.305, 9.379, 126.163 and 780.953, respectively. Using 3 or more abnormal lymph nodes detected by MSCT to predict the area under the ROC curve of axillary HNB in patients with early breast cancer, the area was 0.928, the sensitivity was 82.1%, the specificity was 95.4%, and the accuracy was 94.5%. Kappa test showed that the consistency between MSCT diagnosis and pathological diagnosis was relatively high ( Kappa=0.629, P<0.001). Conclusions:The number of abnormal lymph nodes showed in MSCT is an independent influencing factor of axillary HNB in patients with early breast cancer. Taking 3 or more abnormal lymph nodes showed in MSCT as the threshold can help to predict the axillary HNB status of early breast cancer patients and exempt some of them from unnecessary sentinel lymph node biopsy.
5.Establishment of a preoperative prediction model for axillary lymph node burden in patients with early breast cancer
Xianfu SUN ; Qiang ZHANG ; Lianjie NIU ; Tao HUANG
Chinese Journal of Oncology 2021;43(5):563-568
Objective:To explore the method of predicting high lymph node load in patients with early breast cancer to avoid unnecessary sentinel lymph node biopsy.Methods:The clinicopathological and thoracic multi-slice spiral CT (MSCT) data of 2620 patients with early (cT1~2N0M0) breast cancer treated in the Affiliated Cancer Hospital of Zhengzhou University from January 1, 2014 to August 1, 2018 were collected. According to the postoperative pathological results, the patients were divided into the group with axillaryhigh lymph node burden (HNB) and the non-HNB group. The influencing factors of axillary lymph node burden in patients with early breast cancer were determined by univariate and multivariate analysis, and the diagnostic model of MSCT to HNB was established. The best cutoff value for the diagnosis of HNB was determined through analyzing the receiver operative characteristic (ROC) curve, and the consistency between MSCT diagnosis and pathological diagnosis was evaluated by Kappa test. Results:Among the 2 620 patients, 168 were diagnosed of HNB. Univariate analysis showed that the tumor size, the status of human epidermal growth factor receptor 2 (HER-2), the number of abnormal lymph nodes showed in MSCT, the ratio of the length to the diameter of the maximum abnormal lymph node as shown in MSCT, the condition of the maximum abnormal lymph node door, and the parenchyma of the maximum abnormal lymph node were related to axillary lymph node burden in patients with early breast cancer ( P<0.05). Multivariate analysis showed that the number of abnormal lymph nodes showed in MSCT was an independent influencing factor of axillary HNB in patients with early breast cancer. Compared with patients without abnormal lymph nodes, the OR values of patients with 1, 2, 3 or more abnormal lymph nodes displayed by MSCT and in axillary HNB status were 3.305, 9.379, 126.163 and 780.953, respectively. Using 3 or more abnormal lymph nodes detected by MSCT to predict the area under the ROC curve of axillary HNB in patients with early breast cancer, the area was 0.928, the sensitivity was 82.1%, the specificity was 95.4%, and the accuracy was 94.5%. Kappa test showed that the consistency between MSCT diagnosis and pathological diagnosis was relatively high ( Kappa=0.629, P<0.001). Conclusions:The number of abnormal lymph nodes showed in MSCT is an independent influencing factor of axillary HNB in patients with early breast cancer. Taking 3 or more abnormal lymph nodes showed in MSCT as the threshold can help to predict the axillary HNB status of early breast cancer patients and exempt some of them from unnecessary sentinel lymph node biopsy.
6.Predictors and prediction scores of shunt-dependent hydrocephalus in patients with aneurismal subarachnoid hemorrhage
Lianjie SUN ; Guanjun FENG ; Rixat PARHAT ; Xiaopeng YANG ; Hongxing WU
International Journal of Cerebrovascular Diseases 2023;31(2):151-156
Shunt-dependent hydrocephalus (SDHC) is a common and serious complication of aneurismal subarachnoid hemorrhage (aSAH). The incidence of SDHC after aSAH was 9%-36%, and it is associated with the poor outcome of patients. This article reviews the predictors and prediction scores of SDHC after aSAH.
7.Effects of transcranial magnetic stimulation on the swallowing and brain-stem auditory evoked potentials of dysphagic stroke survivors
Zhongli WANG ; Ming ZENG ; Minmin JIN ; Danni XU ; Yunhai YAO ; Jianming FU ; Fang LIU ; Fang SHEN ; Lianjie MA ; Xuting CHEN ; Xiaolin SUN ; Xudong GU
Chinese Journal of Physical Medicine and Rehabilitation 2023;45(7):620-627
Objective:To observe any effects of contralateral repeated transcranial magnetic stimulation (rTMS) of the swallowing motor cortex on the swallowing and brainstem auditory evoked potentials (BAEPs) of stroke survivors with dysphagia.Methods:A total of 83 stroke survivors with dysphagia were randomly divided into an ipsilesional stimulation group ( n=22), a contralesional stimulation group ( n=21), a bilateral stimulation group ( n=20), and a control group ( n=20). In addition to their conventional dysphagia training, those in the three stimulation groups received 3Hz rTMS while the control group was given fake stimulation. The treatment was administered daily for 20 minutes, 6 days a week, for 5 consecutive weeks. Before and after the treatment, swallowing function was assessed videofluoroscopically and using the Dysphagia Outcome and Severity Scale (DOSS). The oral and pharyngeal stages of swallowing were evaluated using the videofluoroscopic dysphagia scale (VDS). Brain stem conduction was assessed using BAEPs. Results:After treatment the average DOSS scores of all 4 groups were significantly better than before the treatment. The average DOSS scores of the contralesional and bilateral sti-mulation groups were then significantly better than those of the other two groups. The sub-item and total VDS scores of all 4 groups had decreased significantly, but the average score of the bilateral stimulation group was significantly lower than the control group′s average. Ipsilesional stimulation significantly improved the VDS sub-item scores for the triggering of pharyngeal swallowing, laryngeal elevation, and pharyngeal transit time compared with the control group. In the contralesional stimulation group the average total score and the VDS sub-item scores for apraxia, premature bolus loss, oral transit times, the triggering of pharyngeal swallowing, vallecular residue, laryngeal elevation, coating on the pharyngeal wall, and pharyngeal transit time were significantly lower than those of the control group, on average. After the treatment the latencies of BAEP waves I, III and V and the I-III, III-V and I-V interpeak intervals had decreased significantly in all four groups, but the average latencies and intervals of the bilateral and contralesional groups were significantly shorter than those of the control group. The latencies and intervals of the bilateral stimulation group were then significantly shorter than those in the ipsilesional stimulation group on average. The average latency of wave V in the bilateral stimulation group (6.53±0.73ms) was significantly shorter than that in the contralesional stimulation group after the treatment.Conclusion:Bilateral rTMS over the swallowing motor cortex combined with conventional dysphagia training can significantly improve the swallowing of dysphagic stroke survivors.