Objective To compare the obesity-related laboratory results between single abdominal obesity and symmetric obesity in adolescents. Methods A total of 11 460 young students in two provinces were surveyed.Among them 31 students with symmetric obesity (SO group) and 39 students with single abdominal obesity (SAOgroup) were enrolled into the analysis. The age, gender, and body weight were matched between two groups.Blood pressure (Bp), lipids, leptin (LP), fasting plasma glucose (FPG), fasting insulin (FINS), insulin sensi-tivity index (ISI), and serum uric acid (UA) were measured. Liver ultrasonic imaging was performed. The differ-ences of the laboratory results were compared. Results Compared with the SO group, in the SAO group, the inci- dence of fatty liver ( P = 0. 04 ), triglyceride ( P < 0. 001 ), apelipoprotein B ( P < 0. 005 ) as well as FINS, LP,and UA (all P <0. 001 ) were significantly higher, while apolipoprotein A was significantly lower (P <0. 005). LP were positively correlated with FINS (P <0. 001 ) and negatively correlated with ISI (P <0. 001 ). FINS were posi-tively correlated with UA ( P < 0. 001 ) and negatively with ISI ( P < 0. O01 ). Conclusion Adolescents with ab-dominal obesity have higher risks of endocrine and cardiovascular diseases than those with ymmetrical obesity.

OBJECTIVE: To assess the effect of CPAP therapy on sleep quality and quality of life in patients with moderate or severe OSAHS. METHOD: Seventy-two patients diagnosed as OSAHS by polysomnography (PSG) were assigned to receive CPAP therapy for 3 months. At baseline and three months after treatment patients underwent polysomnography (PSG). Analyze the results of PSG, sleep quality, excessive daytime sleepiness, quality of life and the general well-being. RESULT: The lowest average oxygen saturation and the average blood oxygen saturation improved significantly after CPAP therapy, and the longest sleep apnea time and AHI decreased obviously (P < 0.01). Except body pain, the other seven dimensions of SF-36 improved obviously (P < 0.01); ESS, PSQI and GWB also improved (P < 0.05). CONCLUSION For patients with moderate or severe OSAHS, CPAP therapy can obviously improve the sleep quality, excessive daytime sleepiness, improve patients' life quality and the general well-being.
Continuous Positive Airway Pressure ; Humans ; Oximetry ; Polysomnography ; Quality of Life ; Sleep Apnea, Obstructive ; therapy