ObjectiveTo explore the clinical features, treatment, and outcomes of tachycardia induced cardiomy-opathy (TIC) in children.MethodsThe clinical data of 20 children with TIC hospitalized from January 2007 to October 2014 were retrospectively analyzed.ResultsIn 20 patients with TIC, there were 11 infants, one toddler, 5 pre-school age children, and 3 adolescent patients were as follows: 15 cases of atrial tachycardia (distributed in each age group), 3 cases of paroxysmal supraventricular tachycardia (2 in infancy and one in adolescence), and 2 cases of ventricular tachycardia (2 in infancy). After the treatment of anti-arrhythmic drugs, sinus rhythm was restored in 11 patients and ventricular rate was controlled in 5 patients while poor effect of drug was found in one patient who received radiofrequency ablation eventually and got cured. Three patients received radiofrequency ablation after admission immediately. Compared with those before treatment, left ventricular ejection fraction (LVEF) and left ventricular diastolic diameter (LVDD) measured by cardiac ultrasonography were signiifcantly improved after treatment (P<0.01).ConclusionsTIC is common in infancy. Atrial tachycardia is the main type of arrhythmia. Generally drug therapy is the ifrst choice in the treatment of TIC but in older children and those refractory to drug therapy the radiofrequen-cy ablation is chosen.

To study the effect of Sorbaria Sorbifolia extract on anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine.

To explore The clinical value of Multimode ultrasound in evaluating cerebral hemorrhage with intracranial pressure（ICP）. Methods A total of 17 patients with cerebral hemorrhage who received lumbar puncture according to their medical necessity in the ICU of the Affiliated Hospital of Yanbian University from September 2019 to June 2021 were enrolled. The diameter of optic nerve sheath （ONSD） and transcranial Doppler ultrasound （TCD） were performed before lumbar puncture. The patients were divided into elevated intracranial pressure group （9 cases） and normal intracranial pressure group （8 cases），according to the results of lumbar puncture pressure （more than 200 mmH2O was defined as elevated intracranial pressure，and 80～200 mmH2O was defined as normal intracranial pressure）. The Systolic blood pressure，diastolic blood pressure，partial pressure of carbon dioxide，GCS，ONSD and TCD parameters （such as peak systolic velocity，end diastolic velocity，mean blood flow velocity and pulse index of bilateral middle cerebral artery） were compared between the two groups，and the correlation between ICP and ONSD，pulse index（PI） was analyzed. Results （1）The systolic blood pressure，diastolic blood pressure，partial pressure of carbon dioxide （P CO2） and GCS scores between the two groups were not significantly different （all P> 0.05）；（2）The ONSD was significantly higher in the elevated intracranial pressure group［（5.15±0.24） mm vs. （3.97±0.22） mm，t=10.69，P<0.001）］；（3）The systolic peak flow velocity （PSV），end diastolic flow velocity （EDV） and mean flow velocity （MV） between the two groups were not significantly different（all P> 0.05），while the PI was significantly higher in the elevated intracranial pressure group［Right（1.20±0.19） vs.（0.95±0.12），t=3.148，P=0.007）；Left（1.20±0.17） vs. （0.92±0.10），t=3.893，P=0.001）］.（4）ICP was significantly associated with PI （r=0.52，P<0.02） and ONSD（r=0.64，P<0.01）. Conclusion Combine with Ultrasonographic ONSD measurement and TCD can effectively assess intracranial hypertension in patients with intracerebral hemorrhage.