20 cases of cavus deformity of foot were corrected by tarsal wedge osteotomy. The procedure was adopted because this type of deformity had its peculiar anatomical features. 18 feet were followed up postoperatively. and the result was found to be satisfactory 7 months to 5 years alter the operation. The following 2 problems were particularly discussed:1.Cavus defomity is characterized by a marked increase in the longitudinal arch and flexion of the forefoot, with the dome of the arch situating just under naviculo-cuneiform joint. It is therefore deemed most reasonable to perform osteotomy at this point. We think that this procedure gives better result than that recommended by McElvenny and Caldwell or v-osteotomy designed by Japas.2.In cavus foot the result of the operation depends a great deal on an accurate measuremnt of the deformity on the x-ray film. It was suggested that the deformity may be classified as mild, moderate and severe types basing on the measurement of the lateral x-ray film of the affected feet.

Objective To study the effect of rosiglitazone, a ligand of peroxisome proliferator-activated receptor gamma (PPAR?), on the expression of PPAR? in hepatic stellate cells (HSCs) and its effect on the biological characters of HSCs. Methods The activated HSCs were devided into three groups:control, 3??mol/L rosiglitazone group, and 10??mol/L rosiglitazone group. The expression of PPAR?, ?-smooth muscle actin(?-SMA), and type Ⅰ and Ⅲ collagen was detected by means of RT-PCR, Western blot and immunocytochemistry respectively. The cell proliferation was determined with MTT colorimetric assay. The cell apoptosis was demonstrated with flow cytometry. Results The expression of PPAR? at mRNA and protein level markedly increased in HSCs of 10??mol/L rosiglitazone group(t≥4.627, P