Objective To explore the factors that affect the teaching effect of medical statistics study for clinical postgraduates and to provide a reference for further improving teaching Quality. Methods Four hundred and eighty-nine students who had attended Medical statistics in 2013 Fall semester were surveyed by the self-designed questionnaire. The Logistic regression model was used to analyze the factors affecting the learning effect. Results A total of 489 questionnaires were distributed and 488 valid questionnaires were returned (the return rate was 99.80%). 71.11% (347/488) were entirely in favor of giving medical statistics course while 23.98% were relatively supportive. Statistics recognition, learning motivation, finishing homework and the satisfaction of learning were the factors that affect the grades. The OR values are 1.547, 1.723, 1.374, 1.433 for the above four factors respectively. The difference was statistically significant (P<0.05). Conclusion In medical statistics teaching, it can improve students' performance by introducing case study, simplifying the mathematical formula, combi-ning the theory and computer statistical software practice, and improving teaching methods, which helps improve the quality of teaching.

OBJECTIVETo determine the risk factors of urinary calculi in Shenzhen for proper interventions.

METHODSA population-based case-control study including 334 urinary calculi cases and 721 controls was carried out. A total number of 34 factors were analyzed using unconditional logistic regression.

RESULTSSeventeen factors were associated with urolithiasis based on the logistic regression analysis. Ten factors entered the last model of the logistic multivariate regression. The more protein consumption (OR = 2.14, 95% CI: 1.71 - 2.69), positive history of first relatives with urolithiasis (OR = 2.61, 95% CI: 1.70 - 4.01), longer outdoor exposure (OR = 1.39, 95% CI: 1.16 - 1.66) and chronic inflammation of urinary system (OR = 4.09, 95% CI: 1.38 - 12.14) were risk factors of urinary calculi. Higher education background (OR = 0.46, 95% CI: 0.29 - 0.73), drinking more water (OR = 0.59, 95% CI: 0.48 - 0.72), drinking more juice (OR = 0.41, 95% CI: 0.18 - 0.94), more milk and milk product consumption (OR = 0.82, 95% CI: 0.68 - 0.99), vegetable (OR = 0.70, 95% CI: 0.55 - 0.91) and fruit consumption (OR = 0.78, 95% CI: 0.64 - 0.94) were protective factors of urolithiasis.

CONCLUSIONDietary habits were the major influencing factors of urinary calculi. Positive history of family with urolithiasis and social-economic factors were also associated with the disease.

Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; China ; epidemiology ; Feeding Behavior ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Risk Factors ; Urinary Calculi ; epidemiology

Background Results of genetic testing for antipsychotic drugs can guide the rational use of drugs in clinical practice and help improve the clinical symptoms of patients with schizophrenia.However,there is currently limited evidence in China regarding the impact of genetic testing results on medication adherence,social function and drug side effects of antipsychotic drug treatment.Objective To explore the improvement of clinical symptoms,medication adherence and social function in patients with schizophrenia under the guidance of antipsychotic drug gene testing results and examine the safety of drug treatment,so as to provide references for ifor precise treatment of schizophrenia patients.Methods Patients with acute schizophrenia who received hospitalization at Dazhou Minkang Hospital from July 2019 to August 2021 as well as met the diagnostic criteria of the International Classification of Diseases,tenth edition(ICD-10)were selected as research subjects(n=144).Based on random number table,subjects were divided into study group and control group,with 72 cases in each group.Control group received drug treatment based on the doctor's clinical experience,while study group received drug treatment based on the results of gene testing for antipsychotic drug.Both treatments lasted for 12 weeks.At baseline as well as 2,4,8 and 12 weeks after treatment,Positive and Negative Syndrome Scale(PANSS),8-item Morisky Medication Adherence Scale(MMAS-8),Social Functional Rating Scale(SFRS)and Treatment Emergent Symptom Scale(TESS)were adopted for assessment.Result Time effect and group effect of the reducing rate of PANSS,MMAS-8 and SFRS scores in the groups were statistically significant(Ftime=95.251,6.650,14.101,Fgroup=38.055,58.175,128.221,P<0.01).The interaction effect of the reduction rates of MMAS-8 scores in two groups was statistically significant(Finteraction=5.837,P<0.01).The group effect and interaction effect of the severity scores of drug side effects and patient pain scores in two groups were statistically significant(Fgroup=7.553,81.533,Finteraction=8.693,9.322,P<0.01).Conclusion In terms of improving clinical symptom relief,medication adherence,social function and drug side effects,medication for patients with schizophrenia guided by genetic testing of antipsychotic drugs may be more effective than that relying on medication based on clinical experience.