1.Supervision on Measurement of Quality and Safety on Medical Treatment Facility
Liangcai ZHANG ; Jing LI ; Yan HE
Chinese Medical Equipment Journal 2003;0(12):-
To combine "the rule of military medical measurement" with the current situation of medical treatment quality control, the foundation, important component and necessary condition of medical treatment quality control was described. Some idiographic advices of intercoordination and communication in medical measurement institution, the direction and training of special technique, and how to develop compulsion coerciveness checking in base course were given. These are valuable for insuring medical treatment facility in hospital.
2.Effect of myocardial insulin resistance on expression of p38MAPK in ischemic heart failure in rat
Liling ZHENG ; Liangcai CHEN ; Weiping WU ; Hongwei CHEN ; Zhimeng ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2013;(3):169-171
Objective This study was carried out to investigate the effect of myocardial insulin resistance on expression of p38 mitogen-activated protein kinase (MAPK) in ischemic heart failure in rat.Methods Male sprague-dawley rats were subjected either to ligation of the left anterior descending artery (LAD) (n =24) or to sham operation (n =24).After two weeks,cardiac size and function were determined by echocardiography.Glucose and fatty acid (FAO) oxidation rates as well as insulin response were measured in the isolated working heart.The protein expression of p38MAPK was evaluated by Western blotting.Results The infarcted hearts were dilated and had a reduced ejection fraction (ejection fraction <0.50).The basal glucose oxidation was preserved,but the fatty acid oxidation was significantly reduced.Insulin effect on substrate oxidation was significantly impaired for both the decrease in fatty acid oxidation and the increase in glucose oxidation.The protein expression of p38MAPK in infracted hearts wasfisigni cantly reduced(P<0.05).Condusion Myocardial infarction in rats caused partial insulin resistance at the level of substrate oxidation,which was associated with cardiac contractile dysfunction and the expression of p38MAPK.
3.Application of procalcitonin to the diagnosis of pneumonia in patients after kidney transplantation
Daming WANG ; Bin ZHU ; Liangcai DING ; Jinsong ZHANG
Chinese Journal of Emergency Medicine 2011;20(5):524-527
Objective To evaluate the practical value of procaleitonin(PCT)in diagnosis of pneumonia in patients after kidney transplantation.Method A total of 102 patients with pneumonia after kidney transplantation were reviewed.According to the diagnostic criteria of pathogens of pneumonia,32 patients were enrolled in bacterial group and 70 patients in non-bacterial group.The data of the PCT level and the C-reactive protein (CRP) level of the two groups were determined and compared with each other.Results There was significant difference in PCT level between bacterial pneumonia patients after kidney transplantation and non-bacterial pneumonia patients group (P<0.01).The difference in CRP level between bacterial pneumonia patients after kidney transplantation and non-bacterial pneumonia patients group was not significant (P>0.05).The changes of PCT level and the CRP level in 32 patients with bacterial pneumonia after kidney transplantation were not significant (P>0.05),and they were not associated with each other.Conclusions Monitoring the PCT level in patients with bacterial pneumonia after kidney transplantation would have an obviously clinical significance in diagnostic value.
4.Diagnosis of fenestration variation of intracranial artery and vascular anomalies with CT angiography
Liping ZHANG ; Binghang TANG ; Liangcai LI ; Yaqi HE ; Renguo WU
Chinese Journal of Cerebrovascular Diseases 2014;(10):531-535
Objective To investigate the diagnosis of intracranial artery fenestration and its other vascular anomalies with CT angiography ( CTA ) . Methods The image data of 653 patients examined with head CTA and 39 patients diagnosed as intracranial artery fenestration in Zhongshan Hospital Affiliated to Sun Yat-sen University from January 2013 to January 2014 were analyzed retrospectively. The incidence, location,morphology of intracranial artery fenestration, and other vascular anomalies were analyzed. Results (1) In 653 patients,39 (5. 97%) with 41 artery fenestrations were detected. The detection rates of basilar artery fenestration was 3. 37% (n=22),vertebral artery fenestration was 0. 31% (n=2),anterior cerebral artery fenestration was 1. 22% (n =8),anterior communicating artery fenestration was 0. 61%(n=4),and middle cerebral artery fenestration was 0. 76% (n=5),respectively. The post-circulation fenestration was mainly convex lens type (66. 67%,n =17),the anterior-circulation fenestration was mainly fissure type (76. 47%,n=24),and there was significant difference (χ2=7. 411,P<0. 05). (2) In the 39 patients,22 complicated other vascular anomalies. Most of them were unilateral or bilateral fetal-type posterior cerebral arteries (n=10),and followed by aneurysms (n=5). The locations of 5 aneurysms were far from the fenestration,3 located in the communicating segment of internal carotid artery,1 in the top of basilar artery,and 1 in the M2 segment of bilateral middle cerebral arteries. Conclusion CTA can intuitively and clearly reveal the intracranial artery fenestration and other vascular anomalies. But there is no significant correlation between arterial fenestration and vascular anomalies.
5.Investigation of ECG Holter System Based on SD Card
Xiang YAO ; Guangping RUAN ; Wei YU ; Xingyun RUAN ; Liangcai ZHANG
Chinese Medical Equipment Journal 1989;0(01):-
Objective To develop ECG Holter system with SD card as storage medium. Methods Data that used MSP430F449 SCM to acquire 3-channel ECG signal to record SD card through serial peripheral interface were reviewed and analyzed on computer. Results Portable ECG Holter System based on SD card is realized. The using of SD card can enhance storage performance. Conclusion Low-cost, and high-performance solution program is observed.
6.Research on design and application of image analysis system for micro particles
Jing LI ; Xingyun RUAN ; Liangcai ZHANG ; Zhirong XU ; Rongjun WANG
Chinese Medical Equipment Journal 2004;0(07):-
The paper puts forward the design and application of an imaging analysis system for micro-particles.The structure of the system,design theory and its application are discussed in the paper.
7.Working mode conversion for skill improvement of technicians in medical engineering
Xingyun RUAN ; Liangcai ZHANG ; Zhirong XU ; Rongjun WANG
Chinese Medical Equipment Journal 2004;0(09):-
The quality of technicians is the dominate factor to determine the level of medical engineering section.The key to improving technical skills is to do basic jobs.During the Tenth Five-Year-Plan,we not only did many basic jobs and research works in science but did a lot of revolutions in order to accelerate the development of medical engineering and improve the working quality.Compared with the past,we have made great progress and development in standardized management,technology support,technician education,scientific researches,studies,technology level,the quality of service,etc.
8.Quality Control Methods for Important Indexes of X-ray Generators
Yi ZHU ; Xingyun RUAN ; Liangcai ZHANG ; Zhirong XU ; Zhenzhou WANG
Chinese Medical Equipment Journal 1989;0(02):-
The quality control methods are the important to improve the exactness of diagnses and the effectivity of treatment.X-ray imaging quality is an important factor in improving the X-ray diagnosis effect.To serve this purpose,medical engineering personnel should do the X-ray quality control regularly to keep every parameter in accordance with national standards and demands.The quality control methods for several important indexes of X-ray generators are also discussed.[Chinese Medical Equipment Journal,2008,29(2):99-101]
9.Effect of Interventional Therapy of Urokinase on Sudden Hearing Loss
Libin TANG ; Tangying LI ; Liangcai GAO ; Jicai SUN ; Lijie ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2007;13(4):395-396
Objective To observe the effect of interventional therapy of urokinase on sudden hearing loss.Methods65 patients with sudden hearing loss were divided into the treatment group (n=35) and control group (n=30). The patients of the treatment group were treated with urokinase pouring into vertebral artery accordingly into labyrinthine artery in order to improve internal ear microcirculation. Those of the control group were treated with routine drug dropping in vein. All patients of two groups were examined by pure tone test before and after treatment and the therapeutic effect of two groups was compared.ResultsIn the treatment group, the audition of 21 cases recovered, 12 cases got 15~30 dB increasing, 2 cases increased <15 dB. In the control group, the audition of 10 cases recovered, 4 cases got 15~30 dB increasing, 9 cases increased <15 dB and 7 cases had no obvious improvement. There was a significant difference between effects of two groups ( P<0.05).ConclusionThe effect of urokinase on sudden hearing loss is superior to routine drug dropping in vein.
10.Relationship of Th17 cells as well as interleukin (IL)-17A and IL-23R mRNA with psoriasis vulgaris
Diqing LUO ; Yukun ZHAO ; Junhua LIU ; Liangcai WU ; Haiyan ZHANG ; Changyou WU ; Yun LIU
Chinese Journal of Dermatology 2011;44(12):879-881
Objective To assess the number of peripheral blood Th17 cells and mRNA expressions of IL-17A and IL-23R and their correlations with disease severity in patients with psoriasis vulgaris (PV).Methods Tissue specimens were resected from the lesions of 25 patients with PV and normal skin of 10 human controls,and venous blood samples were obtained from 20 of the patients and all of the normal human controls.Reverse transcription PCR and flow cytometry were carried out to measure the mRNA levels of IL-17A and IL-23R in these tissue specimens and quantify the number of peripheral blood CD4+IL-17+ T lymphocytes.Psoriasis area and severity index (PASI) was calculated for these patients.Results A significant increase was observed in the IL-17A and IL-23R mRNA levels in the patients compared with the controls (0.996 ± 0.231vs.0.437 ± 0.096,t =10.572,P < 0.05; 1.006 ± 0.339 vs.0.491 ± 0.196,t =6.015,P < 0.05).The levels of both IL-17A mRNA and IL-23R mRNA were positively correlated with PASI (r,=0.67,0.70,respectively,both P < 0.05).The number of CD4+IL-1 7+ T lymphocytes in peripheral blood showed no significant differences between the patients and controls.No statistical correlation was observed between the counts of CD4+IL-17+ T lymphocytes and expression levels of IL-17A or IL-23R mRNA in psoriatic lesions.Conclusions In patients with PV,there is an increase in the expressions of IL-17A and IL-23R mRNA in lesions,which are correlated with disease severity,while no significant change is observed in the number of peripheral blood CD4+IL-17+ T cells.