1.A Survey on the Non-communicable Disease Prevalence and its Risk Factors Analysis in Residents in Shanghai
Liang-Feng WANG ; Ying WANG ; Shun ZHANG ;
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(05):-
Objective To evaluate the epidemic status of main non-communicable chronic diseases among the residents of Jingan district in Shanghai.Methods Multistage cluster sampling was adopted.960 residents were investigated with questionnaire and physical examination.Results The prevalence rates of Hypertension,diabetes mellitus,Cerebral vessels and Heart-blood were 25.6%,5.8%,3.1%and 5.7%,respectively.The multivarate logistic regression analysis showed that the related risk factors to four non-communicable chronic diseases included family history,the OR(95%CI)1.6(1.2~2.3),6.9 (3.5~13.6),4.5(2.0~10.0),2.2(1.2~4.0)separately.Conclusion Hypertension,diabetes are the main non-communicable disease hazarding the public health.The government and professional institutes should raise the attention on this serious problem and finance more as well as supplying policy support.
2.The effect of apomorphine on visual discrimination learning and reversal learning in rats
Feng SHAO ; Liang LI ; Weiwen WANG
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(3):193-195
Objective Using apomorphine, a potent dopamine receptor agonist and rotating T-maze, the effect of apomorphine on the visual discrimination learning and reversal learning in rats was investigated. Methods All rats were trained in a visual discrimination task (food reward and light stimulus) in rotating T-maze. After reaching the acquisition criterion, rats were trained in a reversal task (food reward and without light stimulus) in the same maze. During the period of visual discrimination task, apomorphine was administrated either 30 minutes prior to learning or after learning immediately. Results The results showed that apomorphine, which was given either 30 minutes prior to visual discrimination learning or after learning, could impair the acquisition of discrimination learning( 259.20±26.29 and 264.00±16.97, compared to 168.00±16.97 and 163.20±20.08) and apomorphine, which was given only after visual discrimination learning, could impair the acquisition of reversal learning (451.20±39.44 compared to 360.00±29.39). Conclusion The results showed that apomorphine, which was given either 30 minutes prior to visual discrimination learning or after learning, could impair the acquisition of discrimination learning and apomorphine, which was given only after visual discrimination learning, could impair the acquisition of reversal learning.
4.X-ray crystallographic analysis and revision of NMR spectral assignments for rhetsinine
Qizhi WANG ; Jingyu LIANG ; Xu FENG
Journal of China Pharmaceutical University 2009;40(6):503-505
Rhetsinine has been isolated from the fruits of Evodia rutaecarpa ( Juss. ) Benth. ~1H NMR and ~(13)C NMR assignments reported previously for rhetsinine were revised on the basis of UV, IR, ESI-MS,~1H NMR, ~(13)C NMR and X-ray crystallographic analysis.
5.Experimental study and preliminary clinical application of microwave coagulation therapy for hepatic malig-nancies after interruption of hepatic blood flow
Jingbing WANG ; Huimin LIANG ; Gansheng FENG
Journal of Interventional Radiology 2001;0(05):-
Objective To investigate the change on the extent of coagulated lesion under various interrupting methods of hepatic blood flow in vivo animal livers, and the clinical effect of combining tran scathcter arterial chernoembolization(TACE) with percutaneous microwave coagulation therapy (PMCT) for primary and metastatic hepatic tumors. Methods Using FORSEA MTC-3-500s microwave coagulator, we performed microwave tissue coagulation in vivo liver of 6 pigs at 60 W, 2 min and of 20 rabbits al 40 W, 2 min with or without the interruption of hepatic blood flow. 27 patients with primary hepatic carcinoma(30 nodules) and 8 patients with metastatic carcinoma( 12 nodules) underwent the combination therapy of 1 - 4 sessions of TACK followed by within 3-10 days by 1 - 3 sessions of PMCT guided by ultrasonography and/or CT. The 42 lesions measured from 2. 3 cm to 15.6 cm were taken place. Results In vivo liver, the greatest dimension of the lesions coagulated by microwave with the interruption of hepatic arterial and portal flow were 22.510.6 mm at 40 W, 2 min and 28. 6?1. 2 mm at 60 W, 2 min, which were markedly larger than those without the interruption (13.3?0.3; and 15.6?0.7 mm, P
6.Experimental Study of Human Esophageal Carcinoma Cells Eca 109 Apoptosis Induced by Sodium Cantharidinate in Vitro
Feng LIANG ; Mingyan WANG ; Dongqing XU
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(03):-
Objective To study sodium cantharidinate induced apoptosis of human esophageal carcinoma Eca109 in vitro. Methods The change of human esophageal carcinoma Eca109 treated with sodium cantharidinate were analyzed by MTT and FCM assay. Results Human esophageal carcinoma Eca109 were treated with sodium cantharidinate for 24 h,the cell proliferation was obviously inhibited(P
7.Simultaneous Determination of Epimedium Glycoside and Other 4 Kinds of Active Ingredients in Xianling Gubao Capsules by Three Wavelength Switching Method
Liang FENG ; Shuhao CHU ; Xiaocai WANG
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(10):68-71
Objective To establish the method for simultaneous determination of epimedium glycoside and other 4 kinds of active ingredients in Xianling Gubao Capsules by three wavelength switching method. Methods An Waters Atlantis T3 C18 column (4.6 mm × 250 mm, 5 μm) was used with the mixture of acetonitrile-0.05% formic acid solution as the mobile phase in gradient elution (0–5 min, 12%–20% A; 5–15 min, 20%–55% A; 15–35 min, 55% A;35–55 min, 55%–76% A; 55.1 min, 12% A; 55.1–60 min, 12% A). Detection wavelength was as follow: 0–30 min, 212 nm; 30–42 min, 246 nm; 42–60 min, 270 nm. The flow rate was 1.0 mL/min. The column temperature was 30 ℃. Results The calibration curves of asperosaponin Ⅵ, psoralen, angelicin, epimedin C, and icariin were in good linearity among the ranges of 101.6–3048 ng, 8.7–261 ng, 7.9–237 ng, 117.2–3516 ng, 78–2340 ng, respectively. In the instrument precision test, stability test, repeatability test, the RSD was less than 3%. The average recoveries were 99.83%, 100.35%, 100.59%, 100.60%, 99.72%, respectively, and all the RSD were less than 3%. Conclusion The method is sensitive, accurate, and separation effect is good, which can provide a basis for quality evaluation standard of Xianling Gubao Capsules.
8.Home-made self-expandable metallic stent therapy for benign or malignant segmental inferior vena cava obstruction
Jingbing WANG ; Huimin LIANG ; Gansheng FENG
Journal of Interventional Radiology 2001;0(06):-
Objective To investigate the clinical value of home-made self-expandable metallic stent therapy for benign or malignant segmental obstruction of inferior vena cava (IVC). Methods 48 patients, including 30 cases of benignancy and 18 of malignancy, were underwent the home-made self-expandable metallic stent endovascular implantation of IVC. Results Of 48 patients, the average obstructive length of IVC were 5.3?2.8 cm. The IVC pressure below the obstruction varied from 21.4?5.1 mmHg of preoperation to 8.4?3.3 mmHg of postoperation(P
9.The study on induced expression of heat-shock protein(HSP)70s in lung carcinoma patients
Feng LIANG ; Jin-Ping ZHENG ; Wen-Liang MA ; Feng WANG ; Tang-Chun WU ;
Cancer Research and Clinic 2001;0(04):-
Objective To analyze the expression level of HSP72 and HSP73,the subtypes of HSP70, in peripheral blood lymphocytes from lung carcinoma patients on both basic and heat injury conditions,and to explore the significance of HSP70 in the development of lung cancer.Methods Lung cancer patients were selected'as experimental group,and the health people with similar age,gender,vocational history and inhabi- tation to the experimental group were chosen as control group.The blood lymphocytes from both groups were isolated,cultured and treated with heat injury at either 37℃or 42℃.The expressions of HSP72 and HSP73 in the isolated lymphocytes were determined by Flow Cytometry.Results There were much higher expressions of HSP72 and HSP73 in control group(21.97?2.40 vs 12.77?0.66)than which in experimental group(HSP72 19.0?2.12 vs HSP73 11.74?0.68,P
10.Recent Research of Traditional Chinese Medicine in the Treatment of HIV-related Diarrhoea
Cuifang WANG ; Feng LI ; Liang NI ; Yuguang WANG
International Journal of Traditional Chinese Medicine 2009;31(5):470-471
Objective To get an overview to studies of traditional Chinese medicine treating HIV-related diarrhea recently, and analysis the predominance and inadequacies of these studies. Methods Articles about TCM treating HIV-related diarrhea from 1981 to 2008 in CNKI, CBM, VIP and MEDLINE were summarized and analyzed by analyzing and found, showing the shortages in the methods, detections, and evaluation of treating this disease.