Gastric cancer is the common malignant tumor of digestive tract,and liver metastasis in patients with advanced gastric carcinoma is the most common cause of death.The early diagnoisis of Liver metastasis of gastric cancer in patients with early diagnosis would help to improve the patient' s quality of life and prognosis.Briefly review the blood,imaging and pathological biopsy method in early diagnosis of liver metastasis of gastric cancer.However it is difficult for this.Researchers over the world should have more exchanges in order to develop guiding principles in the end.

The management of laryngeal cancer and hypopharyngeal cancer has fundamentally changed over the recent years. The optimum treatment protocols should pay close attention to the survival rate and function preservation. The purpose of this article we aimed to define the prevalence of intervention of laryngeal cancer and hypopharyngeal cancer, such as open operation, CO2 laser and non-invasive treatments, and measures that may facilitate standardization of such practices.

Humans ; Hypopharyngeal Neoplasms ; therapy ; Laryngeal Neoplasms ; therapy

0.05).CONCLUSION A similar MMN exists in guinea pigs and human.MMN has a process of development,differentiation and maturation with aging. Guinea pigs can serve as the candidate animal for MMN research.Comparing with ABR,MMN is more sensitive to evaluate the central auditory function.

Colorectal cancer (CRC) is one of the most common digestive system neoplasms in China. Recently, the morbidity and mortality rates of CRC continue to increase with the improvement of people's living standard and the change of the dietary structure. It was accepted that the etiology of colorectal cancer is a multi-factor and multi-step process. However, the mechanism of CRC is still unclear. MicroRNAs (miRNAs) are a class of -21 nucleotide non-coding RNAs and function as a negative regulator of gene expression after transcription, participating in tumor angiogenesis, tumor cell proliferation and invasion. MicroRNA-21 (miR-21), as an important oncogenic RNA, plays a vital role in the development and progression of CRC. This review summarizes the advances in research on miR-21 in colorectal cancer.

OBJECTIVE:To establish the quality standard of Jinwu jiangu capsule. METHODS:Microscopy was used to identi-fy Panax notoginseng;TLC was used to identify Paeonia lactiflora and Sinomenii Caulis;HPLC was used to determine the content of paeoniflorin. The column was ZORBAX SB-C18 with mobile phase of acetonitrile-0.1% phosphoric acid(13∶87,V/V)at a flow rate of 1.0 ml/min,detection wavelength was 230 nm,column temperature was 30 ℃ and injection volume was 10 μl. RESULTS:Microscopy showed P. notoginseng had obvious features;P. lactiflora and Sinomenii Caulis in preparation were well-separated with clear spots. The linear range of paeoniflorin was 0.014-1.412 μg/μl(r=0.999 2);RSDs of precision,stability and reproducibility tests were lower than 2%;recovery was 95.73%-99.48%(RSD=1.54%,n=6). CONCLUSIONS:The method is simple,accurate and reproducible,and can be used for the quality control of Jinwu jiangu capsule.

Objective:To study the correlations between ethics morality, society, psychological cognition and health and disease. Methods:A total of 356 patients were selected to analyze the influence to health and disease from six perspectives that included family ethics, social morality, life style, interpersonal relationship, mental health, and personality traits. Result:Psychosomatic diseases were occurred in 126 cases, and 220 cases of neuro-sis diseases. The disease incidences in the subjects with high cognitive level were significantly lower than those with low cognitive level (P<0. 01). The cognitive levels of family ethics, social ethics, life style, interpersonal rela-tionship, and mental health were closely related to health and disease (P<0. 05). Conclusion:The cognitive lev-els of ethics morality, society, psychology were closely associated with disease. It should be vigorously advocated that the whole society follow the ethics morality standards, to prevent diseases.

Objective]The article summarizes the experience of professor Zhou Enchao in treating diabetic nephropathy . [Methods]Pro.Zhou Enchao treats diabetic nephropathy by pairing drugs; discuses the clinical experience of professor Zhou Enchao in the treatment on diabetic nephropathy from the pathogenesis,treatment,and one case. [Results]Professor Zhou Enchao believes that the disease is caused by Qiyin deficiency, mixed with wet ,Fengxie and blood stasis. Pro.Zhou Enchao treats diabetic nephropathy by pairing drugs,such as astragalus membranaceus and Chinese yam,radix rehmanniae recene and radix scrophulariae,corn stigma and loofah sponge,stiff silkworm and scorpio,salvia miltiorrhiza and earthworm. And these usually lead to good curative effect. [Conclusion]Professor Zhou's clinical experience in treating diabetic nephropathy from pairing drugs is well worth extending in clinic for it always has significant effect.

Acromegaly is mostly caused by a pituitary adenoma secreting growth hormone ( GH ) , which leads to a wide range of endocrine morbidities, with an insidious onset and slow progression.A long-term overproduction of GH results in elevated insulin-like growth factor-1 ( IGF-1 ) level, which in turn, would cause target organ damage and an increased risk for mortality and decreased quality of life.Herein, the literature regarding the progress of drug therapy for acromegaly in recent five years is reviewed.

Objective To investigate the effect of electroacupuncture at bilateral points Quchi on blood pressure variability in hypertensive disease patients.Methods One hundred and two patients were randomly allocated to treatment and control groups, 51 cases each. Methods The treatment group received electroacupuncture at bilateral points Quchi and the control group, no treatment as a blank control. Twenty-four-hour dynamic blood pressure and blood pressure variability were observed in the two groups of patients. Results There were statistically significant post-treatment differences in 24-hour systolic pressure standard deviation (24 hSSD), daytime systolic pressure standard deviation (dSSD) and night systolic pressure standard deviation (nSSD) between the treatment and control groups (P<0.05). There were no statistically significant post-treatment differences in 24-hour diastolic pressure standard deviation (24 hDSD), daytime diastolic pressure standard deviation (dDSD) and night diastolic pressure standard deviation (nDSD) between the treatment and control groups (P>0.05).Conclusion Electroacupuncture at bilateral points Quchi can reduce systolic pressure variability in hypertensive disease patients.