1.Medical equipment risk management comprehensive analysis of quality and safety
China Medical Equipment 2014;(10):101-103,104
Objective: The medical equipment safety risks were avoided and reduce in clinical use. Methods: The security issues to may occur in the process of clinical diagnosis and treatment must be recognized on the multiple links of the medical equipment design, manufacture, management, and the user from the perspective of system security. From the causes of the formation of risk classification, risk assessment, and risk several aspects were analyzed, and work out preventive measures. Results:through the medical equipment quality and safety risk management, take appropriate measures to prevent the happening of the security risks, the influence of the safety risk factors is avoided and reduced. Conclusion:the medical equipment quality and safety risk problem involves many complicated factors, It must be strengthened the quality safety risk of the medical equipment comprehensive analysis, evaluation, management and control.
3.Research progress of CD+4 CD+25 Foxp3 Treg cells in the hematological malignancies
Journal of Leukemia & Lymphoma 2008;17(3):237-240
Thymus derived CD+4; CD+25 regulatory T cells (Treg) are thought to be specific T cells that play an important role in controlling autoimmunity, preventing transplant rejection, restraining anti-infectious immune response, suppressing allogeneic immune respons. More recently, these cells are reported to have the ability of suppressing antitumor immune response. Foxp3 are the most specific protein of Treg. In this review, we will discuss the expression of CD+4 CD+25 Treg in patients with hematological malignancies and its implication for immunotherapy.
4.Retrobulbar injection with triamcinolone acetonide for macular edema caused by retinal vein occlusion
Ming AN ; You WANG ; Liang YING
Ophthalmology in China 2009;18(4):254-256
Objective To evaluate the therapeutic efficacy of retrobulbar injection with triamcinolone acetonide (TA) for macular edema caused by retinal vein occlusion (RVO). Design Retrospective case series. Participants 21 eyes of 21 patients with macular edema caused by RVO. Methods Retrobulbar injection with TA 40 mg was performed on 21 eyes. The visual acuity, intraocular pres-sure, fundus fluorescein angiography (FFA) and macular central thickness under the optical coherence tomography (OCT) were recorded and analyzed before and after treatment. The follow-up duration was 6-11 months. Main Outcome Measures The visual acuity and the macular central thickness of OCT. Result Visual acuity was improved at the end of follow-up in 16 eyes (76.2%) and unchanged in 5 eyes (23.8%). Macular central thickness was (287.55±121.70) μm at the end of follow-up and (617.23±185.58) μm before treatment. The difference was statistically significant(P=0.000). After treatment, the comparison of visual acuity and macular central thickness be-tween CRVO patients and BRVO patients, as well as between ischemic RVO patients and non-ischemic RVO patients had no significant difference (P>0.05). In patients of course less than 6 months, the visual prognosis after treatment is better than that of before treatment (P=0.011, 0.01), while in patients of course more than 6 months, no difference of vision could be detected before and after treatment (P= 0.583). The result of FFA showed decrease of fluorescein leakage. During follow-up, intraocular pressure of all patients was in the nor-real range. Recurrence of macular edema was found in 8 eyes 2 to 6 months after treatment. Conclusions Retrobulbar injection with TA is a safe, effective, and easy method to treat macular edema caused by RVO. Early treatment can get better efficacy. (Ophthalmal CHN, 2009, 18: 254-256)
5.Research on recombinant human PA2G4 family member Ebp1: current status and future perspective.
Chinese Journal of Oncology 2012;34(8):561-565
Adaptor Proteins, Signal Transducing
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chemistry
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metabolism
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Animals
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Apoptosis
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Cell Differentiation
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Cell Line, Tumor
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Cell Proliferation
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Humans
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Neoplasms
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pathology
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Phosphorylation
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Protein Isoforms
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RNA-Binding Proteins
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chemistry
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metabolism
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Transcription Factors
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antagonists & inhibitors