Positron emission tomography,a kind of functional imaging technology might reflect tissue metabolism,and had become an important tool in oncologic study.Radiolabelled glucose,amino acid and ligand are commonly used as PET tracer in meningioma diagnosis.Various tracers reproduce different aspects of meningioma metabolism,while meningioma proliferation rate closely related to functional activity.PET could give us information on meningioma biologic characters in vivo atraumatically.As a functional imaging technology,PET had shown incomparable advantage in differential diagnosis of meningioma,and monitoring therapeutic response of meningioma.

Magnetic resonance diffusion imaging contrasts by water molecule diffusion,reflecting water diffusion status.Owing to the unique mechanism,diffusion imaging is sensitive to anatomic alteration of fiber tract and becomes an important technique in the detection of diffuse axonal injury.Diffusion-weighted imaging shows DAI lesion via emphasizing diffusion composition,diffusion tensor imaging is more sensitive to diffusion anisotropy of the lesion,and fiber tractography can directly demonstrate fiber disruption.MR-diffusion imaging not only improves conspicuity of DAI,but also has grading and prognostic value.

Objective To transmit and browse DICOM images in HIFU remote diagnosis system in Web.Methods Mix-patterned programming of.NET and VC++ was used to create a multi-layers architecture.Results The online compression and web browsing of DICOM images were realized.Conclusion Treatment can be livingly played back and suggestions were proposed for doctors.Medical service in high quality can be provided for remote patients.[Chinese Medical Equipment Journal,2008,29(3):39-41]

Objective: To detect the mRNA levels of AK097082 and BC031001 encoded by psiTPTE22 gene in order to determine whether psiTPTE22 gene is the microarray-detected over-expressed gene in colon cancer and explore the role of psiTPTE22 in carcinogenesis. Methods: RT-PCR and real-time fluorescence quantitative PCR were used to detect the transcription of AK097082 and BC031001 encoded by psiTPTE22 gene in kidney, liver, stomach, lung, and colon cancer tissues and adjacent normal tissues as well as nine cancer cell lines and placenta tissues. Results: RT-PCR showed that only the mRNA of BC031001 encoded by psiTPTE22 was expressed in colon tissues. Real-time quantitative PCR assay and F test confirmed that there was no significant difference between colon cancer and adjacent normal tissues (P > 0.05). So psiTPTE22 was not the specific up-regulated gene in colon cancer detected by microarray. Real-time quantitative PCR assays also confirmed that BC031001 was over-expressed in kidney, liver, stomach, and lung normal tissues but had low expression in corresponding cancer tissues. BC031001 had no expression or weak expression in several cancer cell lines but had relatively high expression in placenta tissues. F tests found that the difference was significant in the expression level of BC031001 between kidney, liver, stomach, and lung adjacent normal tissues and the corresponding cancer tissues (P < 0.05). Conclusions: The mRNA expression of BC031001 encoded by psiTPTE22 gene has negative correlation with several kinds of cancer. Further studies are needed to reveal the mechanism underlying its down-regulation and its role in a carcinogenesis.

Humans ; Nephritis ; etiology ; therapy ; Prognosis ; Purpura, Schoenlein-Henoch ; complications ; therapy ; Sjogren's Syndrome ; etiology ; therapy

Objective This paper aimed to evaluate the effect of preoperative embolization on the intraoperative blood loss of sacrum chordoma.Methods forty patients involved with the spinal chordoma were retrospectively analyzed in this study.The preoperative embolization group consisted of 16 sacrum chordoma patients were embolizationed by gelatin sponge particles (10 male and6 female)age from 35 to 71 years old,(mean 57.9 years) ; and the control group consisted of 4 sacrum chordoma patients (3 male and 1 female),age from 43 to 61 years old(mean 51.8 years).analyzed the predictive value of preoperative embolization in correlation with the intraoperative blood loss.Results The mean blood loss (2025.0 ±818.5)ml of sacrum chordoma in the preoperative embolization group was insignificantly than that (1950.0 ± 802.1) ml in the control group,(P ＞ 0.05).Conclusion The study shows that the preoperative feeding artery embolization of the spinal tumor has no significant effect on the intraoperative blood loss in the surgical excision of the sacrum chordoma.

OBJECTIVE To sum up the cases of hospital infection,in order to further improve the experience of the work of hospital infection.METHODS The investigation of hospital infection situation among inpatients 2005-2007 was reviewed.RESULTS The hospital infection rates in 2005-2007 were 1.81%,1.65% and 1.52%,respectively,mainly in the lower respiratory tract infection and surgical incision.CONCLUSIONS Hospital infection is closely related with the age,the underlying diseases,the antibiotic misuse and the environment.

Objective:To investigate surgical indications and operative techniques of intracranial arachnoid cysts(IAC). Methods:Thirty patients with IAC treated in Nanjing General Hospital of Nanjing Command were analyzed retrospectively.Cyst wall removal and communicated cyst with adjacent cistern or subarachnoid space was performed in 18 patients,cyst-peritoneal shunt in 8 patients,simple resection in 4 patients. Results: Follow-up CT scans after surgery showed that all cysts disappear or shrinked.Conclusion: Cyst-peritoneal shunt was indicated in recurrent cysts after resection,senile patients and infants.Microsurgery resection of the cyst is preferred in majority of the patients,removal of the cyst wall and communicating the cyst with arachnoid cistern were key procedures for preventing relapse.

Objective To investigate the effect of warfarin on coagulation function and hemorheology index in patients with atrial fibrillation. Methods Retrospective a total of 90 patients with atrial fibrillation who underwent anticoagulant therapy from June 2014 to December 2015 in The Fourth People's Hospital of Wenling City were randomly divided into the control group and the warfarin group with 45 cases in each group.The patients in the control group were treated with aspirin, the patients in the warfarin group were treated with warfarin.The indexes of coagulation function and hemorheology were measured before and after treatment, and the effects of warfarin on patients with atrial fibrillation were observed and analyzed. Results After treatment, there was no significant change in coagulation function in the control group, the thrombin time (PT), thrombin time (TT), and partially activated thrombin time (APTT) of warfarin group were significantly increased, the difference was statistically significant (P<0.05), and the coagulation function of warfarin group was significantly higher than that of the control group, the difference was statistically significant (P<0.05).The plasma viscosity, red blood cell index, high shear whole blood viscosity, low shear whole blood viscosity and fibrinogen (FIB) were significantly lower in the two groups, the difference was statistically significant (P<0.05), and the high shear whole blood viscosity, low shear whole blood viscosity and FIB of warfarin group were significantly lower than those of the control group, the difference was statistically significant ( P <0.05 ). Conclusion Warfarin has a potent effect on platelet activation, which can produce anticoagulation by adjusting coagulation function, platelet parameters and hemorheology in patients with atrial fibrillation.

Objective To investigate the expression of phosphodiesterase 5 (PDE5) in clitoral corpus cavernosum and effect of icariin on cyclic GMP (cGMP) levels in vitro. Methods The presence of mRNA coding for PDE5 in clitoral corpus cavernosum was detected by means of RT PCR analysis.The effect of icariin with various concentrations on cGMP levels,which is the target of PDE5 in vivo,was measured by 125 I radioimmunoassay with sildenafil as positive control. EC 50 of icarrin and sildenafil was calculated. Results There was a lane around 800 bp on the agar electrophoresis of the production of RT PCR,which was as long as we designed according to cDNA sequence of PDE5.In the presence of SNP,icariin increased cGMP concentrations in rabbit clitoral corpus cavernosum with increasing dose. Conclusions The results support the proposal that icariin may influence cGMP level by NO cGMP signaling pathway as an inhibitor of PDE5.