1.Ethic thinking on the medical privacy of SARS patients
Chinese Medical Ethics 1994;0(05):-
There is a contradictory between patients' privacy on his condition and the public' civil of knowing facts in the course of preventing and treating SARS.The contradictory should be argued in favor of ethics and be supported by social psychology.
2.Research progress on mechanisms of arsenic trioxide in treating lymphoma
Li MA ; Liang-Ming MA ;
Cancer Research and Clinic 1999;0(05):-
Now the treatment of lymphoma mainly uses combined chemotherapy and radiotherapy.Es- pecially hemopoietic stem cell transplantation is effective in the treatment to the patients with refractory and later stage.During the recent years the domestic and foreign scholars have obtained the encouraging results with arsenic trioxide to treat lymphoma.This article has reviewed the experimental study and the clinical re- search progress about arsenic trioxide in application to lymphoma cells.
3.VEGFR-3 expression in esophageal carcinoma and its significance
Journal of Third Military Medical University 2003;0(24):-
Objective To investigate of the expression of vascular endothelial growth factor receptor 3 (VEGFR-3) and its relationship with the prognosis of esophageal carcinoma. Methods VEGFR-3 in 156 cases of esophageal carcinoma tissues was detected by immunohistochemistry. The follow-up data for 3 years in 47 cases were analyzed. Results The VEGFR-3 expression in esophageal carcinoma tissues with lymph node metastasis was higher than that in those without lymph node metastasis. VEGFR-3 expression was associated with the clinicopathological stages. Analysis of the follow-up data also showed that there was a statistically positive correlation between VEGFR-3 expression and lymph node metastasis in primary tumors (P
4.Histopathology observation of hemorrhagic age-related macular degeneration
Chinese Journal of Ocular Fundus Diseases 2013;29(4):372-375
Ovjective To observe the surgically excised specimens from eyes with hemorrhagic agerelated macular degeneration (AMD).Methods Thirty-six surgically excised specimens were captured from 36 patients with hemorrhagic AMD,26 specimens were diagnosed as occult choroidal neovascular membrane (CNVM),10 specimens were diagnosed as polypoidal choroidal vasculopathy (PCV).All specimens were routinely processed by hematoxylin and eosin,periodic acid-Schiff's stain and Masson stainings.At the maximum horizontal and vertical slice of the specimens,the category and amount of the cells in the specimen were recorded,as well as the relationship between the specimens and the surrounding tissue.Results The 36 specimens are categorized as neovascular membrane dominant (19/36),collagen fiber dominant (6/36),blood clot dominant (8/36) and degenerated thickened Bruch's membrane dominant (3/36).Eighteen occult CNVM specimens and 1 PCV specimen are categorized as neovascular membrane dominant; all 6 collagen fiber dominant specimens are occult CNVM; 1 occult CNVM and 7 PCV specimens are categorized as blood clot dominant; and 1 occult CNVM and 2 PCV specimens are categorized as degenerated thickened Bruch's membrane dominant.The occult CNVM categorized as neovascular membrane dominant present as small blood vessel with single endothelium cell attached; the PCV specimen categorized as neovascular dominant presents as big blood vessel with thick vessel wall under the Bruch's membrane,retinal pigment epithelium and choroidal melanocyte are both observed in the PCV specimens.Conclusion The components of the specimens captured from eyes with hemorrhagic AMD are diversified.
5.Preventive Effect of Flurbiprofen Axetil or Small-Dose Ketamine for Remifentanil-induced Postoperative Hyperalgesia
Journal of Kunming Medical University 2014;(1):106-108
Objective The purpose of this study was to investigate the preventive effect of flurbiprofen axetil or small-dose ketamine for remifentanil-induced postoperative hyperalgesia. Methods 120 anesthetized patients with ASA ⅠorⅡwere randomly divided into three groups. Group A (40 cases) was given 0.5 mg/kg of ketamine by intravenous injection,and 5μg/(kg.min) vein to maintain,group B (40 cases) was given 100 mg of preoperative flurbiprofen axetil by intravenous injection and group C (40 cases) had no flurbiprofen axetil or ketamine which was served as controls. After the treatment, all groups were given continuous intravenous tramadol controlled analgesia (PCIA) . Results After 1 h, 2 h, 4 h and 8 h, the visual analog scale (VAS) of group C was significantly higher than that of group A and group B ( <0.05);after 24 h, there was no statistically significant difference among the three groups in VAS scores ( > 0.05) . The number of fentanyl analgesia were 25 cases and postoperative 24 h PCIA self-control were (8.6 ±4.2) times, which were more than 7 cases and (3.3 ±2.8) times of group A, and 6 cases and (3.2 ± 2.2) times of group B ( <0.05) . Conclusion The preoperative administration of flurbiprofen axetil or intraoperative continuously administered ketamine is able to prevent the occurrence of remifentanil-induced postoperative hyperalgesia, and it will not affect the patient regained consciousness. The method is safe and reliable,so it is worth promoting and popularizing.
6.Granulocyte colony-stimulating factor and hematonosis
Chinese Journal of Tissue Engineering Research 2007;0(14):-
Granulocyte colony-stimulating factor is a glycosylated polypeptide chain cell growth factor that can promote proliferation and differentiation of myeloid progenitors and induce maturation of these cells toward terminally differentiated neutrophils.Granulocyte colony-stimulating factor which functions and effects depend on the combination with specific receptor on the surface of effector cells.With the development of gene cloning technology,ganulocyte colony-stimulating factor recombinant products have been widely used in clinic to provide effective means for the treatment of leucopenia,In recent years,we find the therapy of chemotherapeutics combining with granulocyte colony-stimulating factor is effective in refractory/relapsed/elderly cases of acute leukaemia.Currently,granulocyte colony-stimulating factor is one of important and successful hematopoietic cytokines in clinic.
7.Relationship between expression of vascular endothelial growth factor receptor 3 and lymphangiogenesis in esophageal carcinoma
Journal of Third Military Medical University 2003;0(17):-
Objective To investigate the relationship between the expression of vascular endothelial growth factor receptor 3 (VEGFR 3) and lymphangiogenesis in esophageal carcinoma. Methods VEGFR 3 expression in the esophageal carcinoma tissues from 73 cases was detected by RT PCR and immunobistochemical method. and the relationship between VEGFR 3 and lymphangiogenesis was analyzed. Results There was a statistically positive correlation between VEGFR 3 mRNA expression and lymph node metastasis in primary tumors ( P
8.The significance of DNA-RNA double parameter quantitative analysis in the early diagnosis of laryngeal squamous cell carcinoma
Journal of Third Military Medical University 1988;0(05):-
The relative content of DNA-RNA and the nuclear area/nucleolar area ratio of the hyperplastic tissue,glottic polypus,dysplastic tissue of grade I to I laryngeal squamous cell carcinoma were measured in 33 cases with image analysis technique.It was found that the changes of DNA-RNA content and the ratio of nuclear/nucleolar area were parallel to those of the severity of the carcinoma,and RNA was markedly increased in grade 11 and I dysplastic tissue.On the basis of the current grading of laryngeal pathology,the combined determination of DNA-RNA can provide more sensitive indicators to the stages of malignant degeneration of the laryngeal squamous cell carcinoma.
9.Design of USB Bus power circuits for neuromuscular rehabilitator
Chinese Medical Equipment Journal 2004;0(09):-
This paper analyses the characteristics of USB bus power.Based on the power demand of the circuits for neuromuscular rehabilitator,power voltage transformation circuits are designed for the realization of USB bus power supply.
10.Nosocomial Infections with Acinetobacter baumannii:Clinical Distribution and Drug Resistance
Chinese Journal of Nosocomiology 1994;0(01):-
OBJECTIVE To approach the clinical distribution and drug resistance in nosocomial infections with Acinetobacter baumannii(ABA) to provide the scientific evidence for clinical diagnosis and treatment.METHODS Referring to National Rules of Operation in Clinical Laboratory,215 strains of ABA were isolated.Microscan auto-4 was used to identify strains.And the antibiotic susceptibility test was performed by K-B method.The test results were judged according to CLSI 2007.RESULTS The top four of isolated rates were the intensive care unit(23.3%),department of neurology(17.7%),department respiratory medicine(15.8%) and department of tumor(14.4%).The detection rate of ABA from specimen from respiratory tract was the highest,arriving at 72.6%.The antibiotic susceptibility test showed ABA had been resistant to commonly used antibiotics.The resistance rates to imipenem and meropenem were 22.3% and 23.7%,respectively.The isolated rate of pan-resistant stains was 7.4%.CONCLUSIONS Hospitals should think highly of monitoring and controlling of drug resistance in ABA and prevent nosocomial infections with multidrug resistant strains.