There is a contradictory between patients' privacy on his condition and the public' civil of knowing facts in the course of preventing and treating SARS.The contradictory should be argued in favor of ethics and be supported by social psychology.

Now the treatment of lymphoma mainly uses combined chemotherapy and radiotherapy.Es- pecially hemopoietic stem cell transplantation is effective in the treatment to the patients with refractory and later stage.During the recent years the domestic and foreign scholars have obtained the encouraging results with arsenic trioxide to treat lymphoma.This article has reviewed the experimental study and the clinical re- search progress about arsenic trioxide in application to lymphoma cells.

Micrometastasis is small metastasis at the cellular and molecular level. Early detection of micrometasis through tumor markers can improve the accuracy of TNM staging, prognosis and subsequently treatment for lung cancer patients. Currently, a number of markers with good specificity and sensitivity have been found, including CK19 mRNA, Lunx mRNA, MUC1 mRNA and GPRP mRNA. These markers can be detected using methods such as RT-PCR, immunohistochemistry and western blot.

Granulocyte colony-stimulating factor is a glycosylated polypeptide chain cell growth factor that can promote proliferation and differentiation of myeloid progenitors and induce maturation of these cells toward terminally differentiated neutrophils.Granulocyte colony-stimulating factor which functions and effects depend on the combination with specific receptor on the surface of effector cells.With the development of gene cloning technology,ganulocyte colony-stimulating factor recombinant products have been widely used in clinic to provide effective means for the treatment of leucopenia,In recent years,we find the therapy of chemotherapeutics combining with granulocyte colony-stimulating factor is effective in refractory/relapsed/elderly cases of acute leukaemia.Currently,granulocyte colony-stimulating factor is one of important and successful hematopoietic cytokines in clinic.

OBJECTIVE To approach the clinical distribution and drug resistance in nosocomial infections with Acinetobacter baumannii(ABA) to provide the scientific evidence for clinical diagnosis and treatment.METHODS Referring to National Rules of Operation in Clinical Laboratory,215 strains of ABA were isolated.Microscan auto-4 was used to identify strains.And the antibiotic susceptibility test was performed by K-B method.The test results were judged according to CLSI 2007.RESULTS The top four of isolated rates were the intensive care unit(23.3%),department of neurology(17.7%),department respiratory medicine(15.8%) and department of tumor(14.4%).The detection rate of ABA from specimen from respiratory tract was the highest,arriving at 72.6%.The antibiotic susceptibility test showed ABA had been resistant to commonly used antibiotics.The resistance rates to imipenem and meropenem were 22.3% and 23.7%,respectively.The isolated rate of pan-resistant stains was 7.4%.CONCLUSIONS Hospitals should think highly of monitoring and controlling of drug resistance in ABA and prevent nosocomial infections with multidrug resistant strains.

Objective To explore the influence of different anesthetics on emergence agitation (EA) after general anesthesia. Methods 134 EA patients after general anesthesia were randomly divided into three groups. Group A (n=42), Group B (n=45) and Group C (n=47) was given intravenously parecoxib 40 mg, butorphanol 20μg/kg and tramadol 1 mg/kg, respectively. The improvement of agitation, VAS score and Ramsay score were compared and analyzed among the groups. Results After treatment, the degree of EA in Group A, Group B was significantly lower than that in Group C ( <0.05) . VAS score in all the cases was reduced, and Ramsay score was increased compared with that before treatment ( <0.05) . VAS score in Group C was significantly higher than that in Group A, Group B (<0.05) . Ramsay score in Group B was significantly higher than that in Group A, Group C (<0.05) . After treatment, awaking time and postanesthesia care unit (PACU) stay in Group B was significantly higher than that in Group A, Group C (<0.05) .Conclusions Parecoxib is safe and effective for EA after general anesthesia, it can effectively improve the degree of EA, increase postoperative sedative effect, and shorten PACU stay.

Objective:To evaluate the analgesic effect of botulinum toxin type A (BTX-A) in osteoarthritis model and the changes of Nav1.8 protein expression in spinal ganglia changes.Method:Animal model of knee osteoarthritis (KOA) was established by intra-articular injection of 4％ papain solution 0.3ml into SD rat right knee.After the formation of arthritis,they were randomly divided into two groups at the 2nd day:BTX-A group (n=10):intra-articular injection of 5μl BTX-A 0.1IU;WFI group (n=10):intra-articular injection of 5μl water.No papain or BXT-A was given to the sham group (n=10).At the 1st,3rd,5th day after injection,we tested the pain behavior,thermal pain threshold,and sodium channel 1.8 (Nav1.8) protein expression in spinal ganglion by using immunohistochemistry.Result:Analysis of spontaneous pain behavior showed abnormal gait caused by rat osteoarthritis.Comparing with the WFI group,abnormal gait caused by osteoarthritis improved significantly in BTX-A group.At day 5 it improved more significantly than day 1 and day 3.Thermal pain threshold of BTX-A group increased more than that of WFI group (P＜0.05) at any time point.Abnormal high Nav1.8 protein in model rats decreased in spinal ganglia for BTX-A group.Conclusion:The intra-articular injection of BTX-A may play the analgesic effect in the model of KOA by down-regulating of the expression of Nav1.8 protein in spinal ganglia and reduction in the central sensitization to pain stimulation.

Objective To investigate the relationship between the expression of vascular endothelial growth factor receptor 3 (VEGFR 3) and lymphangiogenesis in esophageal carcinoma. Methods VEGFR 3 expression in the esophageal carcinoma tissues from 73 cases was detected by RT PCR and immunobistochemical method. and the relationship between VEGFR 3 and lymphangiogenesis was analyzed. Results There was a statistically positive correlation between VEGFR 3 mRNA expression and lymph node metastasis in primary tumors ( P

Due to the latent and highly invasive characteristics of liver carcinoma,a majority of patients are frequently not diagnosed until moderate or advanced stage in the disease process,and usually complicate with cirrhosis.Only 15％ -30％ of the patients are eligible for radical resection.The overall survival time is about 3-4 months.Therefore,on the basis of early diagnosis and treatment of liver carcinoma,how to improve the treatment effect of the moderate and advanced liver carcinoma,ameliorate the quality of life and prolong the survival time,becomes the focuses and difficulties both at home and abroad.

Ovjective To observe the surgically excised specimens from eyes with hemorrhagic agerelated macular degeneration (AMD).Methods Thirty-six surgically excised specimens were captured from 36 patients with hemorrhagic AMD,26 specimens were diagnosed as occult choroidal neovascular membrane (CNVM),10 specimens were diagnosed as polypoidal choroidal vasculopathy (PCV).All specimens were routinely processed by hematoxylin and eosin,periodic acid-Schiff's stain and Masson stainings.At the maximum horizontal and vertical slice of the specimens,the category and amount of the cells in the specimen were recorded,as well as the relationship between the specimens and the surrounding tissue.Results The 36 specimens are categorized as neovascular membrane dominant (19/36),collagen fiber dominant (6/36),blood clot dominant (8/36) and degenerated thickened Bruch's membrane dominant (3/36).Eighteen occult CNVM specimens and 1 PCV specimen are categorized as neovascular membrane dominant; all 6 collagen fiber dominant specimens are occult CNVM; 1 occult CNVM and 7 PCV specimens are categorized as blood clot dominant; and 1 occult CNVM and 2 PCV specimens are categorized as degenerated thickened Bruch's membrane dominant.The occult CNVM categorized as neovascular membrane dominant present as small blood vessel with single endothelium cell attached; the PCV specimen categorized as neovascular dominant presents as big blood vessel with thick vessel wall under the Bruch's membrane,retinal pigment epithelium and choroidal melanocyte are both observed in the PCV specimens.Conclusion The components of the specimens captured from eyes with hemorrhagic AMD are diversified.