A new compound and five known compounds were isolated from the ethanolic extract of the leaves of Ilex pernyi Franch. Their structures were established on the basis of spectral analysis and identified as trans-isoeugenyl-α-L-arabinopynosyl(1→6)-β-D-glucopyranoside (1), kaempferol-3-O-sambubioside (2), quercetin-3-O-sambubioside (3), isoquercitrin (4), (+)-syringaresinol-O-β-D-glucopyranoside (5), amarantholidoside IV (6). Among them, compound 1 is a new phenolic glycoside, named as ilexperphenoside A, and compounds 2-6 were isolated from this plant for the first time.

Objective To explore the risk factors of incontinent-associated dermatitis (IAD) in MICU. Methods A retrospective analysis of 141 cases of MICU incontinence in our hospital was done in IAD. The risk factors of IAD were analyzed by single factor and logistic regression analysis. Results The incidence of IAD in MICU fecal incontinence was 43.97%.The risk factors of IAD in MICU incontinence included the amount of defecate,age,body temperature (all P＜0.05). Conclusion The incidence of IAD in patients with MICU incontinence is higher.The risk factor for IAD in patients with ICU incontinence are the amount of defecate, age and body temperature.These high-risk factors should be well-considered and relative measures should be done.

Depression after myocardial infarction is closely related to the theory of ascending and descending of qi and blood. The core pathogenesis is analyzed as disorder of qi and blood, mental damage, uncontrolled upward and downward movement, and pivot movement failure. The treatment method is to regulate qi and blood, invigorate qi and activate blood circulation and restore the rise and fall of visceral qi. Nourishing qi and promoting blood circulation should invigorate qi in the first. Appropriate blood activating drugs should be selected according to the degree of blood stasis, so that the blood circulation is smooth and the spirit has dependence. The key to restoring the normal balance of qi movement of visceral organs is to regulate not only liver ascending and lung descending but also spleen. Clinicians need pay attention to the nature of drug lifting and falling, conforming the physiological functions of the organs, to restore the rising and falling of the qi movement of internal organs.