ObjectiveTo explore the clinical value of respiratory mechanics in neonates with neonatal respiratory distress syndrome (NRDS).MethodsAccording to prognosis,55 newborns with NRDS who had been treated with pulmonary surfactant in our hospital from Jan 2006 to Dec 2008 were divided into 2 groups:44 newborns in survival group and 11 newborns in death group.The dynamical changes of compliance of the respiratory system (Crs),respiratory index (RI) and PA-a O2 were measured during mechanical ventilation.ResultsAt 6 h after mechanic ventilation,there were significant differences in Crs,PA-a O2,OI and RI between the survival group and the death group (t=6.871,-6.450,-10.316,-8.815,P＜0.05 ).In the survival group,RI,PA-aO2 and OI decreased with the time of ventilation,and there were significant differences among the different time point ( F=215.56,147.85,384.64,P＜0.05).In thesurvival group,Crs increased with the time of ventilation,and there were significant differences among the different time point ( F=292,P＜0.05).In the death group,RI,PA-aO2 and OI increased respectively just before dying than at 6 h after mechanic ventilation (t=-5.699,-5.578,-6.924,P＜0.05 ).In the death group,Crs decreased respectively just before dying than at 6 h after mechanic ventilation (t=11.767,P＜0.05 ).Crs was negative correlated with OI,RI and PA-aO2 (r=-0.813,-0.800,-0.859,P＜0.05 ).ConclusionMonitoring in NRDS children's dynamic changes of Crs,RI,OI,PA-a O2 can help observing effect of treatment,guiding ventilator treatment,grasping the opportunity and assessing the prognosis offline in NRDS.

[Objective] To introduce Professor Lian Jianwei's clinical experience in treating cough, insomnia and depression with Ganmai Dazao Decoction. [Methods] Through clinical case studies and analysis of syndrome differentiation, we introduce Professor Lian Jianwei's experience in treating cough, in-somnia, and depression caused by hysteria with Ganmai Dazao Decoction. [Results] Professor Lian Jianwei uses methods of sweet-and-soothing, heart-and-spleen-nourishing and phlegm-reducing-and-spirit-calming respectively to treat cough, insomnia, and depression caused by hysteria with significant efficacy.[Conclusion]Professor Lian Jianwei treats cough, insomnia, and depression caused by hysteria with Ganmai Dazao Decoction with significant effi-cacy. The experience is enlighteningly meaningful to clinical practice.

Acupuncture Therapy ; Child ; Humans ; Male ; Torticollis ; complications ; therapy ; Tourette Syndrome ; complications ; therapy

Objective To detect the genetic diversity of 30 populations of Phyllanthus urinaria from some provinces of China. Methods ISSR was used to analyze the genetic diversity of 30 populations of P. urinaria from Chongqing, Shaanxi, Henan, Yunnan, Guangxi, Guangdong, Zhejiang, Guizhou, Fujian, and Hainan Provinces of China. Results Twenty four primers selected from 60 ISSR primers were used for amplification and a total of 264 DNA bands were obtained, including 245 polymorphic bands and 19 common bands. At species level, the average percentage of polymorphic bands (PPB) was 92.80%. The range of the genetic similarity (GS) value was 0.579 5-0.916 7, with a higher genetic diversity. Cluster analysis showed that the P. urinaria population was roughly divided into three branches: inland branch, coastal branch, and transition branch which located in Yunnan Province; Individual populations presented obvious specificity. Conclusion The genetic diversity of germplasm resources in P. urinaria is higher.

Aged ; Female ; Humans ; Male ; Middle Aged ; Silicosis

The painless needle insertion technique, summarized by Professor WU Lian-zhong during his decades of acupuncture clinical practice is introduced in this article, which is characterized as soft, flexible, fast, plucking and activating antipathogenic qi. The Sancai (three layers) lifting and thrusting manipulation technique is adopted by Professor WU for getting the qi sensation. And features of 10 kinds of needling sensation such as soreness, numbness, heaviness, distension, pain, cold, hot, radiation, jumping and contracture are summarized. Finger force, amplitude, speed and time length are also taken as the basis of reinforcing and reducing manipulations. Moreover, examples are also given to explain the needling technique on some specific points which further embodies Professor WU's unique experiences and understandings on acupuncture.
Acupuncture Therapy ; history ; methods ; China ; History, 20th Century ; History, 21st Century ; Humans ; Needles

Child, Preschool ; Diagnosis, Differential ; Female ; Gonadotropin-Releasing Hormone ; therapeutic use ; Humans ; Hysteroscopy ; Pediatrics ; Puberty, Precocious ; diagnosis ; therapy ; Uterine Hemorrhage ; diagnosis ; etiology ; therapy ; Vaginal Diseases ; diagnosis ; etiology ; therapy

Objective To study the imaging findings of the chest disease due to intravenous heroin abuse. Methods Twenty five cases of clinically confirmed chest disease due to intravenous heroin abuse were retrospectively analyzed. 25 cases had conventional X ray film, 6 cases had CT scanning, and 6 cases had echocardiography scanning. Results On X ray and CT, the following signs were found: lung making manifold ( n =5), small patchy shadow ( n =15), pneumatocele ( n =16), small cavity ( n =16), small node ( n =7), pleural effusion ( n =8), pneumothorax ( n =2), hydropneumothorax ( n =6), pulmonary edema ( n =2), megacardia ( n =11), multiple shaped lesion ( n =20). On echocardiography, tricuspid vegetation ( n =4) and tricuspid insufficiency ( n =4) were found. Conclusion The X ray and CT manifestations of chest inflammation due to intravenous heroin abuse are multiple. The multiple small cavities and pneumatoceles sign are of some value in the diagnosis of lung inflammation due to intravenous heroin abuse among young patients.

Objective To investigate the changes of expression of neuronal nitric oxide synthase(nNOS) after sleep deprivation(SD) in rats,and to study the effects of Xingnaojing on them. Methods Rapid eye movement(REM) SD models(SD group,n=40) were established by the modified multiple platform methods.The rats in SD group were subjected to drug intervention group(n=20) and non-drug intervention group(n=20).Xingnaojing injection was administered to the drug intervention group.Rats in SD group were deprived of sleep for 1,3,5 and 7 d. The expression of nNOS in brain tissues was detected by immunohistochemistry.The rats without SD were severed as cage control group(n=10) and tank control group(n=10). Results The expression of positive cells of nNOS in brain tissues increased with the time of SD,and Xingnaojing decreased the number of positive cells of nNOS.The area density of positive reaction cells in SD group was significantly higher than those in cage control group and tank control group(P

Objective To study the inhibition effects of 10-hydroxycamptothecinc and low molecular weight heparins on human hepatocellular carcinoma(HCC)in nude mice.Methods Metastatic model of HCC was established in nude mice.The model mice were randomly divided into 4 groups:the control group,10- hydroxycamptothecinc group,low molecular weight heparins group,and combined treatment group(10-hy- droxycamptothecinc and low molecular weight heparins).Tumor sizes,tumor inhibition rates,tumor metas- tases,intratumoral microvessel density(MVD),CD_(31)and AFP were evaluated.Results In comparison with the control group and the 10-hydroxycamptothecinc group,the tumor sizes of the low molecular weight heparins and the combined treatment group were significantly smaller;the tumor inhibitor rates were 0 versus 76.6%, 79.8%,94.1%;MVD were 21.1?6.5 versus 17.2?3.1,7.1?2.3 and 4.8?1.8;CD_(31)were 31.7?6.1 versus 26.2?5.2,20.9?4.7 and 19.5?2.4;the incidence of liver metastasis was 80% versus 70%,20% and 10%;lung metastasis was 70% versus 60%,20% and 10%;the peritoneal metastasis was 90% versus 60%,30% and 30%.AFP were(121.9?31.4)ng/ml versus(56.2?37.9)ng/ml,(75.6?28.7)ng/ml and(20.7?12.9)ng/ml. Inhibiting effects of growth and metastasis of HCC in 10-hydroxycamptothecinc group,low molecular weight heparins group and combined treatment group were significantly different from those of the control group(F= 9.074,P