1.Professional distribution analysis on the inpatient with mental illness
Chinese Journal of Primary Medicine and Pharmacy 2016;23(12):1796-1799
Objective To understand the professional distribution of different mental illness,to explore the relationship between mental illness and professional distribution for mental illness early prevention,early intervention and rehabilitation therapy.Methods From January 1,2003 to December 31,2007,mental illness patients'clinical data of psychiatric hospital in Taiyuan city area and psychiatric residency in Taiyuan city hospital were retrospectively analyzed.This paper reviewed diagnosis by a psychiatrist unified training according to the international statistical clas-sification of diseases and related health problems(ICD -10)mental and behavior disorders diagnostic point of classifi-cation standards to ensure that the total effective medical record information collected 16 495 cases(group);17 039 114 cases of control group in the same period of Taiyuan and Taiyuan city public security bureau to provide permanent population statistics data.SPSS 13.0 software was used for statistical analysis of the two data.Results Prevalence of mental illness during he occupation of the population of 0.968%,the average age of 38.11 years,and students around the age of 18 retirees,in the 65 years and other occupations in 30 to 40 years old,these were three good age stages of mental illness,the age of the unemployed(including the unemployed,the unemployed and the unemployed)preva-lence was highest,accounting for 4.223%.Workers and farmers followed,business,service providers and students prevalence was lower.In the case group and control group cadres was statistically significant difference in proportion of occupational composition(U =2.67,P <0.01),there was not statistically significant difference in retirees (U =1.14, P >1.14);Workers(U =52.20,P <52.20),farmers(U =15.25,P <15.25 ),unemployed (U =106.16,P <0.001),the case group was significantly higher than the control group,the difference was statistically significant;Pro-fessional and technical personnel(U =13.97,P <0.001 ),business services personnel(U =30.39,P <30.39), student(U =62.94,P <62.94),and other professional(U =23.88,P <0.001)cases constitute a significantly lower than the control group,the difference was statistically significant.Conclusion The mental illness and the profession have certain relevance,different careers or age prevalence and kinds of disease have obvious difference.
2.Research progress of infectious mononucleosis
Chinese Journal of Postgraduates of Medicine 2016;39(5):475-478
Infectious mononucleosis(IM) was one of the clinical common diseases, caused by epstein-barr virus infection in more than 90%patients. Changes of the surface antigen of the B cells with EB virus infection caused strong immune response of T lymphocytes, besides, helper T lymphocyte, dendritic cells, NK cells also played an important role in the pathogenesis of IM. The incidence of IM was not only closely related with social environment in childhood, but also closely with the number of siblings, birth order, and sunshine factor. In addition to the typical clinical manifestations, IM also can cause a variety of complications, such as spleen rupture and necrotizing mediastinitis , and could be life-threatening. Auxiliary examination means such as state of peripheral blood lymphocyte apoptosis, plasma proteomics, cerebrospinal fluid analysis, load test of EB virus can help to diagnose. Application of antiviral drugs was wider, but hormone was still controversial. Vaccine research progress had been slow, but there were vaccines for human test, which will provide effective measures for the prevention of IM.
3.Research and practice of management of preoperative examination based on quality control circle
Chinese Journal of Practical Nursing 2014;30(35):21-24
Objective To investigate the effect of implementation of QCC (quality control circle) in management of preoperative examination.Methods Through analysis of the common factors of patients' preoperative examination,the QCC was used to manage every parts of preoperative examination,and the nursing process of preoperative examination for resident patients was formulated.The effect of nursing management of preoperative examination before and after the implementation of QCC was investigated and compared.Results The result showed that the degree of satisfaction was significantly higher than before,and the risk incident was significantly lower than before.Conclusions To carry out QCC could improve the efficiency of preoperative examination and the patients' safety,as well as enhance the awareness of the nursing management.
4.Recombinant human transforming growth factor β1 promotes dental pulp stem cells proliferation and mineralization
Weiqian JIA ; Yuming ZHAO ; Lihong GE
Journal of Peking University(Health Sciences) 2017;49(4):680-684
Objective: To explore suitable concentration of recombinant human transforming growth factor β1 (rhTGF-β1) usage and study the effect of rhTGF-β1 on differentiation of dental pulp stem cells (DPSCs).Methods: DPSCs were isolated from the undiseased third molars of people aged 18-25 years and cultured according to instructions in vitro.Different concentrations (1 , 6 , 10 μg/L) of rhTGF-β1 were added to the culture medium to examine DPSCs proliferation by CCK-8 (cell counting kit-8) assay.The suitable concentration was then selected.For differentiation, the DPSCs were incubated for 7 or 14 days with rhTGF-β1 supplemented with osteo/odontoblastic induction medium containing 10 nmol/L dexamethasone, 10 mmol/L b-glycerophosphate, 50 g/L ascorbate phosphate, 10 nmol/L 1,25-dihydroxyvitamin D3 and 10% fetal bovine serum.The cells were then washed 3 times with phosphate-buffered saline and sonicated with 1%Triton X-100 for 30 minutes on ice.Cellular alkaline phosphatase (ALP) activity was assayed with p-nitrophenyl phosphate as the substrate.The enzyme activity was expressed as p-nitrophenyl produced per milligram of protein [bicinchoninic acid (BCA) protein assay kit].To examine mineral nodule formation, the cultured cells were fixed in 4% paraformaldehyde and washed in water, and the mineralization of the extracellular matrix was assayed by 1% alizarin red S staining and elution of staining was examined as optical density (D) under microplate reader.The mean difference was considered significant at 0.05 and 95% confidence interval.Results: The DPSCs had ty-pical fibroblast morphology and could form mineral nodules after being cultured with osteo/odontoblstic induction medium for 14 days.6 μg/L rhTGF-β1 significantly promoted the DPSCs proliferation on the 3rd and 5th days.After the incubation of osteo/odontoblastic induction medium, the DPSCs with the 6 μg/L rhTGF-β1 increased ALP activities compared with the control;D values in the 6 μg/L rhTGF-β1 group was 0.31±0.03, while the control group was 0.02±0.01(P<0.05).The total protein content in the 6 μg/L rhTGF-β1 group was (2 775.46±83.54) mg/L, and the control group was (1 432.20±110.83) mg/L (P<0.05).To eliminate the cells proliferation influence, relative ALP activities, which was defined as the total ALP divided by the total protein content, the 6μg/L rhTGF-β1 group was 6 times higher than the control group.Alizarin red S staining showed increased mineral nodule formation in the rhTGF-β1 group.The elution of staining under microplate reader also showed more optical density in the 6 μg/L rhTGF-β1-treated cells (0.83±0.02) than that in the control groups (0.55±0.05, P<0.05).Conclusion: 6 μg/L rhTGF-β1 could significantly promote DPSCs proliferation and odontoblastic differentiation in vitro.
5.Data quality control study of data warehouse in the TCM literature
Jing LIU ; Lihong LIU ; Jing WANG ; Lirong JIA ; Ye TIAN
International Journal of Traditional Chinese Medicine 2012;34(1):55-57
Data quality issues of TCM structured data warehouse system is very important.This paper analyzed the data quality issues from the data repository to the data extraction,cleansing,transformation,loading (ETL) into the data warehouse process and established the principle of corresponding control,and researched improving data quality measures to ensure the success of data warehouse and right decision support.
6.Low plasma total cholesterol concentration:may be related to malnourished hospitalized patients
Zhongxin HONG ; Jia WANG ; Zhihua LIU ; Li WU ; Lihong ZHANG
Chinese Journal of Clinical Nutrition 2009;17(5):290-293
Objective To investigate low plasma total cholesterol concentration in hospitalized patients,which is associated with malnourishment.Methods A total of 358 inpatients who were treated in our hospital from January 1 to February 1,2009,were enrolled.The relationships between low plasma total cholesterol (TC) level and other parameters were analyzed.Results Irrespective of women or men,the morbidities of low plasma TC,low plasma albumin,low plasma total proteins,low plasma triglyceride (TG) and low hemoglobin (Hb) levels were highly consistent with the result of subjective global assessment (SGA) (P <0.05).Plasma TC concentration was positively correlated with albumin,TG,Hb,lymph cells number,and body mass index (P<0.05).TC levels were different between men and women (P <0.0001).Meanwhile,low plasma TC level was not correlated with age,but it was correlated with total parenteral nutrition.Conclusion Low plasma TC concentration may relate to malnourished hospitalized patients.
7.Comparison of the therapeutic effect,safety and quality of life of different operation time on ureteral calculi after extracorporeal shock wave lithotripsy
Hongyong HAN ; Min WEI ; Lihong ZHAO ; Fenmei JIA
Chinese Journal of Primary Medicine and Pharmacy 2017;24(17):2607-2610
Objective To study the effect,safety and quality of life of different operation opportunity on the patients with ureteral calculi after extracorporeal shock wave lithotripsy.Methods From July 2015 to September 2016,45 patients with ureteral calculi who received lithotomy after 2 times of extracorporeal shock wave lithotripsy (ESWL) in our hospital were selected as observation group.Another 45 cases who received more than 3 times of ESWL and turend to lithotomy at the same period were selected as control group.The clinical effect was compared between the two groups.Results The total effective rate of the observation group was 95.56% (43/45),which was significantly higher than 71.11% (32/45) of the control group,the difference was statistically significant (χ2=9.680;P=0.002).The incidence rates of obstruction(17.78%),infection (26.67%) and hydronephrosis (24.44%) in the observation group were significantly lower than those in the control group (42.22%,64.44% and 60.00%),the differences were statistically significant (χ2=6.402,12.947,11.660;P=0.011,0.000,0.001).The scores of diet [(83.2±12.6)points],spirit[(85.6±13.3)points],sleep[(87.3±15.4)points] and psychological score[(85.9±13.6)points] in the observation group were significantly higher than those of the control group [(75.1±11.4)points,(76.2±11.6)points,(77.4±13.2)points and (73.2±10.7)points],the differences were statistically significant (t=3.003,4.038,3.514,4.513;P=0.004,0.000,0.001,0.000).The satisfaction rate of patients(97.78%) of the observation group was significantly higher than 77.78% of the control group,the difference was statistically significant (χ2=8.389;P=0.004).Conclusion Patients with ureteral calculi who received more than 2 times of ESWLand the stones in the body has not been effectively removed,should be accepted as soon as possible stone surgery treatment,it can improve the clinical effect,reduce the incidence of complications,improve the quality of life of patients.
8.Stability of Ceftazidime and Ormidazole Chloride Sodium Injection with Sequential Intravenous Dripping
Chunye WANG ; Ting WANG ; Wenbin LI ; Yunli ZHAN ; Lihong JIA
China Pharmacist 2017;20(8):1505-1507
Objective: To investigate the compatible stability of ceftazidime and ormidazole chloride sodium injection with sequential intravenous dripping.Methods: The contents and the absorption curves of ceftazidime and ormidazole sodium chloride injection in the mixture were determined by UV.The appearance of the solution was observed and the pH value was determined.Results: With the quality ratio of ceftazidime to ormidazole at 1∶25, 1∶50 and 1∶100, the mixture color changed from light yellow to light pink in 40, 45 and 48 min, respectively, and gradually deepened with the extension of time.With the quality ratio of ormidazole to ceftazidime mixture at 1∶400, 1∶800 and 1∶1 600, the color was stable in 3 h.There were no evident changes in the appearance, pH, content and absorption curves.Conclusion: The solution containing ormidazole and ceftazidime might have changes in color.Clinical pharmacist suggests that ormidazole chloride sodium injection be given intravenously, and then sequentially followed by ceftazidime.
9.Mediating effect of trait angeron relationship between childhood psychological maltreatment and online aggressive behavior in college students
Lu ZHANG ; Lihong LIU ; Tonglin JIN ; Yanru JIA
Chinese Mental Health Journal 2017;31(8):659-664
Objective:To explore the relationship among childhood psychological maltreatment,online aggressivebehavior and trait anger in college students.Methods:Totally 442 college students (226males,216 females,aged 16-25 years) were surveyed with the Psychological Maltreatment Scale (PMS),Adolescent Online Aggressive Behavior Scale (AOABS) and Trait Anger Scale (TAS).The bias-corrected percentile bootstrap method was used to analyze the mediating effect of trait anger between childhood psychological maltreatment and online aggressive behavior.Results:The scores of PMS,AOABS and TAS were positively correlated each other(r =0.44,0.37,0.48,Ps <0.01).The PMS scores had a significantly direct effect on the AOABS scores,its estimate was 0.27.The PMS scoreshad a significantly indirect effect on the AOABS scores through TAS scores(95% CI:0.15-0.34).Conclusion:It suggests that the trait anger may be related to childhood psychological maltreatment and online aggressive behavior,and trait anger may play a partial mediating role between childhood psychological maltreatment and online aggressive behaviorin college students.
10.Impact Factors of Hand Hygiene among Healthcare Workers:Investigation and Analysis
Lihong SONG ; Huixue JIA ; Jianxia JIA ; Xiuli ZHAO ; Yanchun ZHAO ; Linping LI ; Liuyi LI
Chinese Journal of Nosocomiology 1994;0(01):-
OBJECTIVE To know the compliance and it′s impact factors of hand hygiene of healthcare workers.METHODS The wards and healthcare workers were sampled randomly.Survey the compliance,qualified rate and impact factors of hand hygiene of healthcare workers when they didn′t know to be observed by special training staffs.RESULTS The compliance and the qualified rate of hand hygiene was 30.2% bothly,and be affected by the time before or after operation,occupations and work post.The factors causing low qualified rate were anenough time and improper technique for washing hand,and drying hand wrong.CONCLUSIONS The hand hygiene for healthcare workers in hospitals should be strengthened.