Objective To build relationship model of personality, life style and mental health for medical students. Methods 869 medical students were surveyed with Eysenk Personality Questionnaire, Symptom Check List 90(SCL-90), common condition questionnaire, to describe the situation of medical students mental health and personality, and a relationship model was set up by structural equation modeling. Results The situation of mental health for medical students was well. Male students showed significantly higher lie than female students. The only children showed significant higher lie than those having siblings. Neuroticism, life style, lie, sleep time everyday, boarding and lodging in middle school, friends, only child, degree of parents attention had significant direct influence on mental health (β =0.508, 0.136, 0.100, 0.082, 0.076, -0.057, 0.057, 0.051 ). Neuroticism, friends and sleep time everyday affected mental health in an indirect way through life style (β = 0.044, - 0. 008, 0.007). Only child affected mental health in an indirect way through boarding and lodging in middle school (β = -0.026). Lie affected mental health in an indirect way through neuroticism (β =0. 195). Conclusion The important effects of personality, life style on mental health are further supported in this study.

Hyperglycemia has direct and indirect impact on the occurrence and develop-ment of stroke. At present, hyperglycemia is considered as an independent risk factor for stroke. Hyperglycemia directly involves in cellular and vascular injury through activating polyol pathway, forming advanced glycosylation end product, activating protein kinase C and the hexosamine pathway. Moreover, hyperglycemia involves in vascular injury through the indirectly pathway such as lipid metabolism, glycosylated hemoglobin and insulin. Controlling hyperglycemia may effectively reduce the incidence of stroke and improve the prognosis in patients with stroke.

Objective To observe the correlation between active vitamin D3 level and sarcopenia development in elderly patients in plateau regions and the changes in the correlation factors for sarcopenia under the invention of active vitamin D3 (Calcitriol,Cal),and to observe whether Cal could improve the muscle function.Methods 90 patients were assigned to the normal control (Con) arm,and 120 patients with sarcopenia were assigned to the sarcopenia (Sar) arm to receive different oral doses of Cal as intervention (0.25 ug/d for low dose group including 60 patients and 0.25ug bid for high dose group including 60 patients) Before and after the intervention,levels of 1,25-(OH)2D3 and the inflammatory factors TNF-α,IL-6,IL-10,and hs-CRP were detected using ELISA;HOMA-IR,BMI,and ASMI were calculated;and walking speed and grip strength were measured to observe the correlation between 1,25-(OH) 2D3 level and sarcopenia,the changes in these indicators from before to after intervention,and the efficacy and safety of oral Cal for sarcopenia.Results Prior to intervention,compared with the Con arm,1,25-(OH)2D3 level,IL-10 level,ASMI,walking speed and grip strength were significantly reduced (P＜0.01),and HOMA-IR,IL-6,TNF-α and hs-CRP were significantly elevated (P＜0.01) in both dose groups;intervention with Cal produced significant increases in 1,25-(OH)2D3 and IL-10 levels,significantly improved walking speed and grip strength (P ＜0.05),significant decreases in HOMA-IR,IL-6,TNF-α,and hs-CRP (P＜0.05),which were more marked with higher dose,but no significant changes in ASMI.From before to after intervention,there were no significant changes in BMI or hepatic/renal function,blood calcium,or blood phosphorus in either group.Conclusions The development of sarcopenia is associated with reduced 1,25-(OH)2D3 level.Cal can lower the inflammatory factors IL-6,TNF-α,and hs-CRP,and elevate IL-10,providing anti-inflammatory and immunoregulatory actions;improve muscle function and strength;and improve insulin resistance.BMI is irrelevant to the management of sarcopenia.Cal is safe at the oral dose up to 0.5 tμg/d.

Study the development of the surgery methods for breast cancer according to the biological characteristics of breast cancer. Reviewing the operations for 25years and the relative literature, I put forward the principle for choosing the methods of the surgery. The improving radical treatment for breast cancer is the first choice to hospitals. It will take time for them to keep the breasts by means of complex treatment. The surgery of breast cancer emphasize individuation, humanization, lowering hurt and justification. The complex treatment mainly by means of surgery has an effective cure in the long run.

Objective To explore the reason and the degree of dysphoric mood of family members of children with scoliosis, and then make out some countermeasures to ameliorate these dysphoric mood. Methods Divided 64 family members of children with scoliosis into the observation group and the control group randomly. Using nursing intervention in the observation group and none in the control group. Evaluated the mood of 2 groups by the end of research by using the Zung Self-judged scale and the questionnaire. Results Different causes have induced different degree of dysphoric mood of family members of children with scoliosis. After using the nursing intervention, there were significant difference between the 2 groups in dysphoric mood, P

Objective To explore the relationship between asymptomatic lacunar cerebral infarction and blood pressure variability (BPV) in senile patients with essential hypertension.Methods According to the results of the cranial magnetic resonance imaging (MRI),160 patients were divided into two groups:96 cases of hypertension combined with lacunar cerebral infarction group and 64 cases of simple hypertension group.Their levels and variability blood pressure were investigated by 24 hours ambulatory blood pressure monitoring.All markers included 24 h average systolic blood pressure variation (24 h SBPV),24 h average diastolic blood pressure variation (24 h DBPV),the day average systolic blood pressure variation (dSBPV),the night average systolic blood pressure variation (nSBPV),the day average diastolic blood pressure variation (dDBPV),the night average diastolic blood pressure variation (nDBPV),the standard deviation (SD)and variable coefficient (CV) of morning peak systolic blood pressure and diastolic blood pressure.Results 24 h SBPV,dSBPV,nSBPV,24 h DBPV,dDBPV,nDBPV was increased significantly in hypertension combined with lacunar cerebral infarction group compared with those in simple hypertension group (0.15±0.03 vs.0.11 ± 0.02,0.14 ± 0.02 vs.0.10 ± 0.03,0.14 ± 0.03 vs.0.10 ± 0.08,0.13 ± 0.08 vs.0.11 ±0.04,0.14 ±0.02 vs.0.11 ±0.07,0.14 ±0.05 vs.0.09 ±0.02),and there was significant difference (P ＜ 0.05).SD and CV of morning peak systolic blood pressure and diastolic blood pressure in hypertension combined with lacunar cerebral infarction group was higher than that in simple hypertension group [(15.37 ±4.55) mmHg (1 mmHg =0.133 kPa) vs.(13.53 ±2.26) mmHg,(13.64 ±4.95) mmHg vs.(9.80 ± 3.46) mmHg,0.141 ± 0.048 vs.0.113 ± 0.037,0.145 ± 0.056 vs.0.105 ± 0.036],and there was significant difference(P ＜ 0.05).Conclusion The BPV,especially morning blood pressure surge BPV are increased significantly in the hypertension combined with lacunar cerebral infarction group compared with that simple hypertension group,BPV increase is one of the important risk factors of cerebral infarction.

ObjectiveTo investigate the perioperative nursing experience in patients with renal cell carcinoma treated by cryoablation.Method The clinical data of 34 patients with renal cell carcinoma treated by cryoablation were retrospectively analyzed to summarize the perioperative nursing strategies.Results All the patients lived through the operations.The complications after the surgery occurred in 7 cases,with bleeding in 4 cases,urinary fistula in 1 case and wound infections in 2 cases.All the complications were cured by active treatment.After following up for 6 months,all the tumors showed liquefaction and necrosis and no one relapse. Conclusion Active and effective nursing intervention is the key point for the success of cryoablation.

Objective To investigate the effect of 1,6-diphosphate(FDP)on neonatal hypoxic-ischemic encephalopathy(HIE)combined with myocardial damage.Methods 62 cases of HIE in newborn with myocardial damage were randomly divided into two groups:32 cases of the treatment group and 30 cases of the control group.Control group were giren conventional treatment and the treatment group were giren FDP 250mg /(kg?d)by intravenous drip for 10 days for 1 course of treatment.Each case was tested serum creatine kinase(CK)and isoenzyme(CK-MB)within hospitalization 12 hours and after treatment.The two groups were observed with clinical symptoms and signs disappeared,the ECG changes and CK,CK-MB changes.Results Clinical signs and symptoms of treatment group disappeared soon,and serum CK,CK-MB returned to normal rate is high compared with the control group significantly.Conclusion Exogenous FDP has a certain therapeutic effect on moderate to severe HIE with myocardial damage,contributes to recovery of heart and brain function.

Background Atrial fibrillation (AF) is one of the most prevalent arrthythmias. Hypertension independently accounts for more AF cases than any other risk factors. Therefore,prevention of risk factors in patients with essential hypertensives(EH) is important for early prevention and diagnosis of AF. However,only a few data are available regarding left ventricle remodeling in essential hypertensive patients with atrial fibrillation(EH+AF). Objective To study the characteristics of left heart remodeling and function and its clinical significance in EH+AF,and predict some risk factors of AF. Methods All 561 patients were recruited which included EH+AF(n=224),EH alone(n=171),AF alone(n=166) with normal subjects as control(n=157). Interventricula septal thickness at end-diastole(IVSTd),posterior left ventricular wall thickness at end-diastole(LVPWTd),left ventricular end-diastolic dimension(LVEDD),left ventricular end-systolic dimension(LVESD),left atrial dimension (LAD),left ventricular ejection fraction stroke volume(LVEF),stroke volume(SV)cardiac output(CO)were measured with echocardiography. Left ventricular mass(LVM),left ventricular mass index(LVMI)and relative wall thickness(RWT)were calculated. Results LVM,LVMI,IVSTd,LVPWTd,LVESD,LVEDD,LAD,RWT in the EH+AF group were significantly greater than those in the AF alone or EH alone patients(P

This text induced the experimental and clinical researching progress of Buyang Huanwu decoction, a well-known prescription formulated by WANG Qing-ren in Qing dynasty, in order to enrich documents for studyingperipheral neural diseases clincially.