OBJECTIVE: To provide reference for the application of automatic tablet packing machine in the inpatients dispensary.METHODS: The working principle and flow,the main structure and function of the automatic tablet packing machine used in our hospital were introduced,and its application value was evaluated and the problems remained to be dealt with were pointed out.RESULTS: The automatic tablet packing machine had the advantages of high accuracy and efficiency,and reduced working intensity,however,the costs for the packaging and consumables,and the low drug quality were the problems remained to be solved.CONCLUSIONS: Automatic tablet packing machine is suitable for the dispensing of oral single dose of tablets for inpatient patients,and it helps to improve the work quality and the service level in the dispensary for inpatients.

Objective To summarize the clinical experience of 3% sodium chloride in treatment of chronic heart failure with hyponatremia. Methods The 102 patients suffering from chronic heart failure with hyponatremia were treated with water limit, vasodilator, cardiotonic, diuretics, angiotensin-converting enzyme inhibitor, angiotensin Ⅱ receptor antagonist and 3% sodium chloride. Cardiac functional capacity classification (NYHA), treatment effect and hyponatremia level were compared between pre- and post- treatment. Results After treatment, heart function was statistically different as compared with that of pre-treatment (χ2=150.26, P＜0.05). The 58 cases showed distinct effect, 37 cases moderate effect, 7 cases no effect, and the percentage of total effect was 93.1%. The hyponatremia of patients with different level of heart function were (139.4±22.6) mmol/L, (138.2±23.3) mmol/L, the difference had a statistics significance compared with pre-treatment hyponatremia which were (122.9±20.5) mmol/L, (120.5±26.8) mmol/L (t=2.02, 2.04, P＜0.05). Conclusions Proper diuresis and sodium salt supplement could help to reduce the malignant risk of the patients suffering from chronic heart failure with hyponatremia and to improve the prognosis.

Objective To investigate the clinical and pathological characteristics between types 1 and 2 endometrial uterine cancers.Methods The clinical materials of 9 437 patients with uterine cancer were collected with retrospective analysis from 62 hospitals during 2000 to 2010.Results The mean age of type 1 endometrial cancers was less than type 2.There were more young patients in type 1 endometrial cancers.The mean menopause age of type 2 endometrial cancers was greater than type 1.The mean age of menarche,obesity,diabetes,hypertension,infertility,and nulliparous were not significant differences between types 1 and 2 endometrial cancers.There were more patients with advanced tumor,deep myometrium invasion,estrogen receptor (ERs) negative,progesterone receptor (PR) negative,P53 positive,lymph vascular space involvement,cervical stromal invasion,adnexal metastasis,and lymph node metastasis in type 2 endometrial cancers.Conclusions Type 2 endometrial uterine cancers occurred in elder people with more pathological risk factors and more malignant biological activities.

Peritoneal adhesion is one of the common complications of abdominal and pelvic operations,the impact of which is immense in terms of human suffering and substantial socio-economic burden.There is an urgent need for a more effective understanding of the disease process and its etiology,to evaluate the pharmacologic,mechanical,and surgical adjuvant strategies to minimize peritoneal adhesion formation.

Objective To study the dynamic changes in calcineurin-? expression in lung tissue of rats under simulated weightlessness condition,and the influence of ligustrazine(tetramethylpyrazine) on the changes in its expression.Methods The rat model of simulated weightlessness condition was reproduced by suspending the rat by tail in-30?.Thirty healthy Wistar rats were randomly divided into 3 groups(10 each): control group,suspended group(rat was suspended by tail for 7 days) and ligustrazine group(rat was suspended by tail and ligustrazine was given for 7days).In the ligustrazine group,the ligustrazine was gavaged in a dose of 1.5mg/kg(once a day).The expression of calcineurin-? in lung tissue was determined by immunohisochemistry and Western blotting.Results It was revealed by immunohisochemistry and Western blotting that the level of expression of calcineurin-? in lung tissue of the animals in suspended group was significantly higher that in control group and ligustrazine group(P0.05).Conclusion The level of expression of calcineurin-? in rat lung tissue may be increased obviously under the simulated microgravity condition,while ligustrazine treatment may down-regulate the calcineurin-? expression.

Objective To observe the effects of Tangshenjiaonang (TSJN) on biochemistry, renal function and hemorheology of alloxan and achromycin induced diabetic nephropathy rats. Methods The diabetic nephropathy rats induced by alloxan and achromycin were divided into 5 experimental groups. compared with control group, to observe the changes of the indicators shown about. Results TSJN can significantly decrease the level of SCr, BUN, CCr, FIB, plasma viscosity and UAER (P

This paper studies the characteristics of biomedical engineering education mode in USA as well as its history in China.The practice and research on education mode of biomedical engineering in our institute is introduced as a reference for biomedical engineering education.

Objective To explore the relationship between maternal homocysteine (HCY), folic acid, 5, 10 methylenetetrahydrofolate reductase (MTHFR) genotypes(677C→T) and occurrence of congenital heart disease (CHD) in offspring. Methods HPLC technique was used to measure the level of total plasma HCY in 32 mothers of CHD children and 23 mothers of normal children, radio immunoassay was used to measure folic acid, and MTHFR genotypes were detected by PCR RELP analysis. Results The incidence of hyperhomocysteinemia(Hhe) (34%,11 cases) in CHD maternal group was significantly higher than that in normal maternal group( P

OBJECTIVE:To prepare compound Weifu emulsion and to observe its therapeutic effect on infantile eczema METHODS:The emulsion was prepared with a formulation consisting of Scutellaria,Chinese Angelica,Chuanxiong and dimethyl silicone oil etc and the quality control method was established RESULTS & CONCLUSION:This preparation is stable in quality and feasible in quality control;The effective rate in treating infantile eczema has reached 90% and no obvious adverse reactions were found This emulsion is worthy of recommendation for clinical use

It is documented that nearly half of the global population have been infected with Helicobacter pylori (Hp).In Chinese consensus report on management of Hp infection,bismuth quadruple therapy composed of proton pump inhibitor,bismuth and two antibiotics is recommended as the first-line Hp eradication regimen.However,large doses of oral antibiotics and PPI often disrupt the well-balanced host-microbial symbiotic state,and impair the protective effect of biological barrier.Furthermore,the alteration of microbial composition secondary to eradication therapy might be associated with the increased adverse effects of Hp eradication therapy and re-infection.This paper summarized the advances in study on effects of Hp eradication therapy on intestinal microecology and the advantages of probiotics supplementation in Hp eradication therapy.