Medicine, Chinese Traditional ; methods ; trends

Coronary Disease ; diagnosis ; Humans ; Medicine, Chinese Traditional ; methods

Objective To investigate the efficacy of microendoscopic tubular retractor system (METRx) in the management of lumbar intervertebral disc herniation. Methods By using the METRx system with modified instruments, the lumbar discectomy was performed in 550 cases. During the operation, patients were placed in a knee-chest sitting position, and the instrumentation was utilized into the vertebral canal through the ligamenta flava. Results The patients were followed for 6~36 months (mean, 21 months). According to the Nakai criteria, the curative outcomes were “excellent” in 478 cases (86.9%), “good” in 60 cases (10.9%),“fair” in 6 cases (1.1%), and “poor” in 6 cases (1.1%). The 6 cases with “poor” results obtained “fair” results after a re-operation of lateral recess enlargement and residual nucleus removal under microendoscope. Conclusions Lumbar discectomy with the utilization of the METRx system is minimally invasive, safe and effective.

Objective:To investigate the effect of estrogen on the expression and distribution of IL-1 in the remodeling osteoporotic alveolar bone.Methods:Ovariectomy was performed on 30 female SD rats and sham operation on 15(control group).When osteoporosis was developed in the 30 ovary-removed rats,the left maxillary molars of all the rats were extracted.On the following day 15 of them were treated with intramuscular estrogen injection at 20 ?g/kg once every 3 days(treatment group).Another 15 rats with ovary removed received no treatment(osteoporosis group).7,30 and 60 days after teeth extraction 5 rats were killed respectively in each group.IL-1 expression in alveolar bone was examined immunohistochemically,and semiquantitative analysis of cellular-staining intensity was done by microphotometry.Results:The positive IL-1 expression were mainly located in the osteoclasts,vascular endothelial cells and fibroblasts.7 days after teeth extraction the cellular-staining intensity of IL-1 in control group,osteoporosis group and treatment group was 0.11?0.019,0.36?0.038 and 0.18?0.025 respectively(control or treatment group vs osteoporosis group,P

OBJECTIVE To evaluate the efficacy of plasma sterilization system,observe and comprehend the(methods) and mechanisms of plasma sterilization.METHODS In application of plasma(sterilization) system,the(sterilization) processes were observed.The efficacy of this new system was shown by a biological test and chemical test.Comparative observation was conducted on the effective use time of wire of high-frequency electrode that had been sterilized in plasma sterilization system and Formalin smoke respectively.RESULTS The instrument that had been sterilized in plasma sterilization system all passed the tests and could be used immediately,manipulation of(plasma)(sterilization) system was easy,the effective use times of electrode′s wire were extended.CONCLUSIONS Plasma sterilization system can achieve effective sterilization with low(humidity),and no-toxicity.With shorter sterilization cycle time and lesser damage to surgery instruments,this new system improves the margin of safety and reduces(processing) costs.

Arthropathy, Neurogenic ; Child ; Coxa Vara ; Hand Deformities, Congenital ; Humans ; Male ; Synovitis

Apoptosis ; Carcinoma, Squamous Cell ; diagnosis ; genetics ; metabolism ; therapy ; Cell Proliferation ; Chromosome Aberrations ; Early Diagnosis ; Epigenesis, Genetic ; Humans ; MicroRNAs ; genetics ; metabolism ; Mouth Neoplasms ; diagnosis ; genetics ; metabolism ; therapy ; Neoplasm Invasiveness ; Neoplasm Metastasis ; Polymorphism, Genetic

AIM: To study the protetive effects of Danshenhonghua Injection (Radix Salviae Miltiorrhizae,Stigma Croci,etc) on acute cerebral ischemia in rats. METHODS : The model of acute incomplete cerebral ischemia was built by ligaturing bilateral carotid arteries. Cerebral index,cerebral water content ,capillary permeability of brain,and the change of cerebral morphology in rats were observed. RESULTS : The cerebral index,cerebral water content,capillary permeability of brain decreased remarkably with 7.2,14.4mg?kg -1 of Danshenhonghua Injection,and the injury of brain tissue was also abated by Danshenhonghua Injection significantly. CONCLUSION : Danshenhonghua Injection has the protetive effects on acute cerebral ischemia.

BACKGROUND: We have previously reported that marine algae polysaccharide derivant can significantly promote bone cell growth.OBJECTIVE: To observe the effect of marin algae polysaccharide derivant in treatment of osteoporosis.METHODS: Sixty female Wistar rats were randomly divided into control group, treatment group and model group. There were 20 rats in each group. The rats in treatment group and model group were respectively treated with retinoic acid to induce osteoporosis. The rats in treatment group were gavaged the marine algae polysaccharide derivant 10 mg/kg, and the rats in model group were gavaged the glucose 10 mg/kg orally for 14 days. Changes of rat femur bone histological examination and histomorphometry parameters were observed.RESULTS AND CONCLUSION: The mean Trabecular Number (Tb.N), the mean Trabecular Thickness (Tb.Th) and the percent Trabecular Area (Tb.Ar%) were significantly decreased in the model group compared with control group. The mean trabecular separation (Tb.Sp) was greatly increased. After intake of marine algae polysaccharide derivant, Tb.N, Tb.Th and Tb.Ar% of the treatment group were significantly more than that of the model group. The Tb.Sp was obviously reduced. These indicate that marine algae polysaccharide derivant can increase bone mass and have a therapeutic and preventional effect on the osteoporosis.

Objective · To investigate the gender-related metabolomic differences in human saliva. Methods · The saliva metabolomic profiles of 5 male and 5 female healthy volunteers with matched age, body mass index (BMI), living and tooth-brushing condition were acquired using ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry. Metabolites were identified using publicly accessible databases and further confirmed individually with standard compounds. Both multivariant and univariate statistics were conducted to find inter-gender differences.Results · Forty-eight metabolites in human saliva were identified including 13 amino acids, 6 choline metabolites, 15 carnitines, 4 sphinganine metabolites,7 lysophosphatidylcholine and 3 organic acids. Levels of phenylalanine, acetylcarnitine, propionylcarnitine, butyrylcarnitine, isobutyrylcarnitine,isovalerylcarnitine and sphinganine were higher in the saliva of females than that of males. Conclusion · Rich metabolic information present in human saliva with significant gender diffference which ought to be taken into consideration in study on the metabonomics of saliva.