Australia is a country with strict drug administration, which is hard for its market access. Chinese Medicine Registration Act 2000 enacted by Victoria State of Australia established the legal status of traditional Chinese medicine in Victoria State, which made Australia the first one of western nations to legislate traditional Chinese medicine. We should take advantage of this opportunity to give in-depth analysis of laws and regulations on traditional Chinese medicine in Australia to push on traditional Chinese medicine to enter the Australia market. By analyzing the regulations of traditional Chinese medicine in Australia market, we put forward the following strategies on traditional Chinese medicine accessing Australia market: first, we should strengthen cooperation of Chinese and Australian governments; secondly, we should focus on analysis of regulations of drugs of Australia, thirdly, we should establish technical standard of herbal drugs in conformity with international standard; finally, we should strengthen traditional Chinese medicine culture exchange.

We analyzed and sorted the policies and regulations of traditional medical management in international markets which also affecting traditional Chinese medicine and summaried current situation of barriers of policy and regulation of Ttraditional Chinese medicine.After thoroughly analyzing the reasons of barriers of policy and regulation of traditional Chinese medicine,we found that the reasons lied in culture difference between China and western countries,quality of traditional Chinese medicine,low level of R&D and manufacturing,incomplete domestic laws and regulations of traditional Chinese medicine,lack of anti-technical barriers to trade service system.In the end of this paper,we came up with some countermeasures of barriers of policy and regulation when traditional Chinese medicine accessing international markets.

Traditional Chinese medicine is the few field of owing independent intellectual property in China, the implement of intellectual property strategy is important for the long-term development of traditional Chinese medicine enterprises. At present, traditional Chinese medicine enterprises still remain many problems in intellectual property protection, such as weak awareness of intellectual property protection, lack of intellectual property protection professional personnel, inadequate investment in R & D and low innovation level. These problems caused huge losses in practice to traditional Chinese medicine enterprises. After analyzing the status of intellectual property protection of traditional Chinese medicine enterprises, we put up with some concrete measures of intellectual property protection of traditional Chinese medicine considering the reality of these enterprises.

AMP-Activated Protein Kinases ; genetics ; Heart Diseases ; Humans ; Syndrome

Objective To study the clinical effect and value of the combination of dexamethasone and calcium agent assisted oxytocin on preventing postpartum hemorrhage.Methods 128 cases of maternal of clinical information were reviewed,and which were divided into control group and observation group randomly.The control group was immediately infused muscle note 20IU of Oxytocin and the observation group(n =64) was given 5％ of glucose and 100ml 10％ of glucose acid 10ml calcium.And then give 20IU oxytocin after pending.Lastly,give the two groups comparison of blood-producing capacity and the number of cases of blood-producing.Results Ater observation groups in fetal foetus blood-producing capacity of 2h and 24h,the number of cases of blood-producing less than the control group,and both have significant statistical differences (all P ＜ 0.01).Conclusion The combination of dexamethasone and calcium agent-assisted application of oxytocin can prevent postpartum hemorrhage,better clinical effect,which should be promot in clinical application.

Objective To explore the safety and effectiveness of dexamethasone and calcium gluconate combined with oxytocin to prevent postpartum hemorrhage.Methods 128 maternal patients with full-term delivery were divided the patients into two parts randomly:the control group and the observation group,of which contained three groups(A,B,C).The patients were all given 20 u oxytocin.As to observation,group A:before 10-15min of cutting skin,give 10mg of dexamethasone and 10 ml 10％ calcium gluconate rapid intravenous infusion,group B:give 10mg intravenous infusion of dexamethasone after babies were boro,group C:before 10 ～ 15min of cutting skin,give 10mg of dexamethasone and 10ml 10％ calcium gluconate rapid intravenous infusion and then give 10mg dexamethasone after babies were born.The control group wasn't given that medicine,and only give them 20 u oxytocin when babies were born.At last,give contrast of total amount of bleeding,ill reflecting of medicine and the other symptom after 24h.Results The amount of bleeding of observation group A,B,C were (277.3 ± 44.5) ml,(286.8 ± 52.7) ml,(301.8 ±60.9) ml,respectively.The amount of bleeding of the control group was (422.9 ± 78.2) ml.The observation group and control group had significant differences(t =-0.699,0.481,-0.407,all P ＜ 0.01),and there was no significant difference between group A,B,and C (P ＞ 0.05).And this two groups had no bad reflection and the other symptoms.Conclusion Dexamethasone and calcium gluconate combined with oxytocin to prevent postpartum hemorrhage has great efficacy and safety.This method must be extended.

Objective To explore the effect of high-fat diet on IRS-1 and IRS-2 expressions of fatty liver in rat. Methods After the rats were fed a high-fat diet (n=7) and a standard chow(n=7) for 8 weeks, insulin sensitivity,lipid metabolism, TNF-α and hepatic mRNA and protein expressions of IRS-1 and IRS-2 were measured. Results Compared with the normal control, the high-fat diet group displayed the elevated levels of insulin resistance,FFA and TNF-α.Hepatic IRS-1 mRNA expression and IRS-1 protein content were reduced by 28% and 32%(P<0.01),respectively. Similarly, hepatic IRS-2 mRNA and IRS-2 protein content were also reduced by 30% and 27% (P<0.01), respectively. Conclusions High-fat diet results in a significant decrease in expressions of mRNA and protein of hepatic IRS-1 and IRS-2 in rats, which might be one of the molecular mechanisms of insulin resistance in liver steatosis induced by high-fat diet

This article analyses the pre-management methods and measures for the youth science fund projects granted by the National Natural Science Foundation of China.Systematic procedures include mobilization,preliminary research preparation,professional training and counseling,modifying the application,form and content examination,which can improve efficiency of the National Natural Science Foundation of China youth science project management.

AIM: To observe the effect of aminoguanidine (AG) on hemodynamics and lung capillary permeability in acute lung injury (ALI) in rabbits. METHODS: 24 rabbits were equally divided into four groups: saline group, endotoxin group, AG group and AG plus endotoxin group. In AG plus endotoxin group, endotoxin was injected to animals to make an ALI model, 25mg/kg AG was injected following that and let this sustain 3 hours. Meanwhile, mean arterial pressure (MAP), mean pulmonary arterial pressures (MPAP) and blood gas analyses were observed during this period. At the end of the experiment, broncho-alveolus lavage was performed, pathologic samples were treated routinely and lung wet weight/dry weight ratio was calculated. RESULTS: After endotoxin injection, MAP and arterial oxygen pressure (PaO 2) decreased, and MPAP increased significantly. The injection of AG had little effect on MAP, but AG could markedly decrease MPAP and increase PaO 2. Cell count in broncho-alveolus lavage fluid (BALF) was less in AG plus endotoxin group than in endotoxin group. Although AG did not affect total protein in BALF, low molecular weight proteins decreased in AG plus endotoxin group by the assay of electrophoresis. Tissue wet weight/dry weight ratio also decreased in this group. Pathologic study showed that there were fewer inflammatory cells and less lung edema in AG plus endotoxin group. CONCLUSION: AG could improve hemodynamics status and attenuate acute lung injury induced by endotoxin in rabbits. [

Objective To explore the effect of high-fat diet on IRS-1 and IRS-2 expressions of fatty liver in rat. Methods After the rats were fed a high-fat diet (n=7) and a standard chow(n=7) for 8 weeks, insulin sensitivity,lipid metabolism, TNF-? and hepatic mRNA and protein expressions of IRS-1 and IRS-2 were measured. Results Compared with the normal control, the high-fat diet group displayed the elevated levels of insulin resistance,FFA and TNF-?.Hepatic IRS-1 mRNA expression and IRS-1 protein content were reduced by 28% and 32%(P