1.Observation of curative effect of Xiaoer Chiqiao Qingre granule in the treatment of infantile upper respiratory tract infection
Ling ZHA ; Yuhang GU ; Ping LI
Chinese Journal of Primary Medicine and Pharmacy 2017;24(8):1229-1231
Objective To observe the clinical curative effect of Xiaoer Chiqiao Qingre granule in the treatment of infantile upper respiratory tract infections.Methods 100 children with upper respiratory tract infection were selected,and they were randomly divided into observation group and control group,50 cases in each group.The observation group was treated with Xiaoer Chiqiao Qingre granule,the control group was given ribavirin effervescent granules.The effects of the two groups were observed.Results The total effective rate of the observation group was 96%,which was significantly higher than 78% of the control group (x2 =9.500 6,P < 0.05).The fever,symptoms and signs of improvement time in the observation group were better than those in the control group.Conclusion Xiaoer Chiqiao Qingre granule in the treatment of infantile upper respiratory tract infection can defervesce quickly,and has quick curative effect,so it is worthy of promotion.
2.The influence on the quantity of the template DNA on the results of the automatic fluerescent detection of STR multiplex amplification
Lihua GU ; Yuan PING ; Li CHENG
Chinese Journal of Forensic Medicine 1986;0(02):-
Objective For the purpose of exploring the influence exerued by the amount of template DNA on the results of automatic fluerescent detection. Method For the purpose of buiding the optimal amount of template DNA amplified, we have analyzed different amount of template DNA (9947A) by 3100 Genetic Analyzer with the multiplexing Profiler Plus Kit. Results The optimal amounts of template DNA amplified were between 0.31ng and 2. 5ng by using 3100 Genetic Analyzer. Conclusion It will produce the incorrect analytic results if the amounts of template DNA were too high or too low.
3.Clinical Treatment Study of Iron Deficiency Aremia Associated Helicobacter Pylori Infection
lie-ping, HUANG ; man-li ZHUANG ; guo-ping, BEI ; cheng-ping, GU ; yan-hua, LI
Journal of Applied Clinical Pediatrics 1986;0(01):-
Objective To explore the therapy measurement of iron deficiency anemia(IDA)associated helicobacter pylori(HP)infection among children.Methods Eight hundred and ninty nine cases entrusted children aged from 2 to 7 years old were measured hemoglobin(Hb),mean corpuscular volume(MCV)mean corpuscular hemoglobin(MCH),mean corpuscular hemoglobin concentration(MCHC)and serum ferri,serum fettin(SF),HP-IgG antibodies.Divided the HP-IgG positive cases into two groups for treatment,The treatment group adopted omeprazole,amoxicillin and metronidazole to cure them for two weeks,then oral ferrous sulfate sugar liquid.The contrast group purely take the ferrous sulfate sugar liquid.After eight weeks re-examined the Hb and SF.Results Totally 279 cases were diagnosed as Hp-positive,620 as HP-negative and 99 children diagnosed as IDA,among the 99 cases IDA,58 cases with HP infection(20.8%) and 41 cases with non-HP infection(6.7%).That means the number of IDA cases with HP infection was higher than those with non-HP infection(?2=39.46 P
5.Discussion on taking Nd-YAG laser measures vocal cords nodules and polyps.
Qiang HUANG ; Ping HUANG ; Li-De GU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(1):72-73
Female
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Humans
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Laryngeal Diseases
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surgery
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Laser Therapy
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Lasers, Solid-State
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Polyps
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surgery
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Sarcoidosis
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surgery
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Vocal Cords
6.Comparison of clinical characteristics of new onset ulcerative colitis in the elderly versus the youth and middle-aged patients
Ping ZHAO ; Chuanfeng LI ; Yumin LYU ; Fang GU ; Peng BAI
Chinese Journal of Geriatrics 2014;33(5):503-506
Objective To analyze the differences in the clinical characteristics,endoscopy,pathology and therapy between the patients with new onset ulcerative colitis(UC) in the elderly versus youth and middle-aged patients.Methods A review analysis was carried out in the 178 hospitalized patients with UC in Third Hospital of Peking University from 1994 to 2010.The patients were divided into two groups according to the age of onset:UC onset at age of 60 years and older were enrolled in elderly group; UC onset at age less than sixty years were enrolled in youth and middle-aged group.The data of clinical manifestation,endoscopy,pathology,laboratory test,the severity of disease classification and therapy were analyzed and compared between the two groups.Results The elderly group consisted of 21 men and 6 women.The youth and middle-aged group consisted of 83 men and 68 women.The ratio of male was higher in elderly group than in youth and middle-aged group (77.8% vs.55.0%,P<0.05).No significant difference in the clinical type of UC was observed (P>0.05).The ratio of abdominal pain in elderly group was lower than in youth and middle-aged group (44.4% vs.78.8%,P<0.05).There were no significant differences in other symptoms,laboratory test and the severity of disease between the two groups (all P>0.05).The ratio of Grade Ⅰ and Ⅱwas much higher in the elderly than in youth-middle-aged group(70.4% vs.39.9%,P<0.05),but the ratio of Grade Ⅲ and Ⅳ was much lower in the elderly than in youth-middle group(29.6% vs.60.1%,P<0.05).No significant differences between the two groups were found in the extent of disease,pathological characteristics and therapy (all P>0.05).Conclusions Compared with the youth and middle-aged patients with onset UC,the ratio of male patients was higher,the ratio of abdominal pain was lower,and the severity of endoscopic manifestation was less in the elderly patients with onset UC.
7.The effect of glococorticoid in treatment of class IV lupus nephritis
Ping LUO ; Yanhui LI ; Hua GU ; Al ET
Chinese Journal of Immunology 1985;0(06):-
Objective:To investigate the effect of glucocorticoid on treating class IV lupus nephritis(LN) by comparing the content of serum transforming growth factor beta(TGF ? 1).Methods:The study consisted of 33 objects,15 health controls as well as 18 cases of IV LN.The level of serum TGF ? 1 was analyzed by ELISA.Results:The level of serum TGF ? 1 was greatly reduced after the patients were treated with glucorcorticoid.Conclusion:Timely and sufficient glucocorticoid may prevent IV LN from developing into glomerulosclerosis.
9.Protective effect of Ginkgo biloba L. extract on PC12 cell damage induced by rotenone and MPP~+ in vitro
Mingwei WANG ; Ping GU ; Li LIU ; Yanyong WANG ; Dongshen CUI
Academic Journal of Second Military Medical University 1982;0(02):-
Objective:To study the protective effect of Ginkgo biloba L.extract(EGB) on PC12 cell damage induced by rotenone and 1-methyl-4-phenylpyridium(MPP +). Methods: PC12 cells damage model was induced with different concentrations of rotenone and MPP + and were treated with EGB . Then cell morphology was observed; survival rate and ultracellular dopamine (DA) level were determined by MTT assay and ELISA assay, respectively. Results: MPP + -induced damage was attenuated by pre- or co-treatment with EGB at 0.35,0.70 and 1.40 mg/ml, while rotenone-induced damage was attenuated with EGB only at 1.40 mg/ml.The DA concentrations of extracellular at 2 mmol/L MPP + (6.875?0.201) ng/ml and 10 ?mol/L rotenone (5.321?0.167) ng/ml increased to ( 7.595?0.139 ) ng/ml (P
10.EFFECTS OF ANDROGEN ON LEARNING AND MEMORY ABILITY AND HIPPOCAMPUS NEURONS IN SAMP8 MOUSE
Huixian CUI ; Sha LI ; Ping GU ; Geming SHI
Acta Anatomica Sinica 1955;0(03):-
Objective To explore the effect of androgen on learning and memory ability and neurons in hippocampal CA1 region in senescence accelerated mouse prone strain/8(SAMP8).Methods Thirty 7-month-old male SAMP8 were randomly divided into sham-operation control group,castrated group and androgen replacement therapy after castration group.The dose of testosterone undecanoate(TU) was 37.4mg/(kg?15d).The capability of learning and memory was observed 45 days later through the Morris water maze(MWM) test and the change of neurons in hippocampal CA1 region was detected and analyzed by HE staining,immunohistochemal method and computer pathological image analysis system.Results 1.In the MWM test,the escape latency of castrated group were significantly prolonged(P0.05).2.With HE staining,neurons in hippocampal CA1 region of castrated group were found with diffused vacuolar degeneration,and sparse and disordered cellular arranpement.The cell nucleuses were karyochrome and karyopycnosis.The number and optical density of A? immune positive neurons were markedly higher than those of other groups(P