Epistaxis is a common otorhinolaryngological emergency with complex etiological factors and varied clinical manifestations. The key to epistaxis treatment is accurate diagnosis and adequate hemostasis. Electrocoagulation is a reliable, safe and effective treatment for epistaxis. However, there are still several deficiencies in application of the commonly used electrocoagulation surgical products. This paper introduces a new type of radiofrequency head incorporating the dynamic circulatory functions of drip, irrigation, hemostasis and aspiration. We aim to achieve noninvasive, effective and accurate hemostasis in the treatment of epistaxis or nasal sinus surgery.
Humans ; Epistaxis/surgery* ; Electrocoagulation ; Treatment Outcome ; Paranasal Sinuses

Objective:To examine the expression of TRAF 6 in ovarian carcinomas ,discuss the relation between expression level and clinical characteristics of ovarian carcinomas and study the clinical significance .Methods: Specimens from 102 patients with ovarian carcinomas managed in our hospital between Augest 2001 and December 2009 were included in this study .Immunohistochemical staining was used to detect the expression of TRAF 6 in ovarian carcinomas and normal tissues .All the specimens were confirmed by pa-thology for ovarian carcinomas and normal tissues by HE staining .Then, the correlation between the expression and clinical characteristics of patients was analyzed .Furthermore ,survival analyses were performed according to the Kaplan-Meier method.Results:The positive expression rate of TRAF 6 in ovarian carcinomas and normal tissues was 68.6% and 20.5%, respectively.TRAF6 expression was significantly associated with tumor stage and distant metastasis ( P<0.05 ) .According to the survival analysis of 102 ovarian carcinomas patients ,cases in the TRAF6 low-expression group showed poorer overall survival rate when compared with low -expression group ( P<0.001 ) .Conclusion: These results indicate that the expression of TRAF 6 was closely related with in the progression of ovarian carcinomas and may have clinical utility in the prediction of prognosis of ovarian carcinomas .

To summarize the risk factor,pathogenic bacteria,medical and prevention progress of ventilator-associated pneumonia.It is beneficial to avoid the risk factor of ventilator-associated pneumonia,and to reduce morbidity and mortality.

Objective　To further investigate the balance (relative presence) of Th1 and Th2 subsets at the sites of rheumatoid inflammation,and to understand how about the expression of IL-18 in patients with rheumatoid arthritis (RA),and what the relationship exists between expression of IL-18 and rate of Th1/Th2 in RA,and between IL-18 level and activity of the disease.Method　Expression of IFN-γ,IL-4,and IL-18 mRNA in peripheral blood mononuclear cells (PBMC) from 16 patients with RA and 15 healthy subjects was detected by semi-quantitative RT-PCR.Results　① PBMC from patients with RA was found to contain greater levels of IL-18 mRNA than that from healthy subjects (P＜0.01).② IL-18 mRNA levels were correlated with IFN-γ mRNA (relative coefficients:r＝0.836,P＜0.05).③ IL-18 mRNA levels were associated with the disease activity as assessed by levels of erythrocyte sedimentation rate (r＝0.753,P＜0.05).Conclusion　IL-18 is among a matrix of inflammatory cytokines produced abundantly in patients with RA and is associated with induction of IFN-γ and activity of the disease.

Stem cell therapy provides immense hope for restoring the impaired cardiomyocytes .However, it has been debated on the effectiveness , mechanisms , and survival of the donated cell population in the ischemic myocardial milieu .Protective paracrine effect of stem cells on cardiomyocytes gradually arose great attentions .Exosomes , as typical representative of paracrine effect of stem cells, are 30-100 nm in size and tiny microvesicles released by cells in response to different physiological states , and enriched in pro-teins, messenger RNAs, and miRs characteristic of parental stem cells , represent great potential for treating cardiovascular diseases . Recent studies show that exosomes from different kinds of stem cells can effectively promote cardiac function by means of promoting the donated cell survival , proliferation and angiogenesis in the ischemia heart .The aim of this review is to summarize current research ef-forts on exosomes from different kinds of stem cells , including their potential mechanism to develop a potentially viable therapy for the treatment of impaired cardiomyocytes via promoting cardiomyocytes survival , proliferation and angiogenesis;inhibiting inflammatory re-sponse and cardiac fibrosis after myocardial infarction .

Obejective To analyze the related papers on nursing competency in China from 2004 to2014,and to learn the current status and developing trends of nursing competency,so as to provide reference for further research and development of nursing competency.Methods All literature related to nursing competency from 2004 to 2014 were searched in the China National Knowledge Infrastructure(CNKI),VIP Database for Chinese Technical Periodicals (VIP),and Wanfang database.Bibliometric analysis methods were used to analyze the distribution time,area,journal distribution and research categories by using Microsoft Excel.Results Totally 199 articles related to nursing competency were collected and the number of publications increased in recent years.About 78.89％ (157/199) papers were published in the statistical source journal and 34.17％ (68/199) papers were focused on survey research about nursing competency.Conclusions Nursing competency have been paid more attention to,but the quality of the literature still need to be improved.

Optic coherence tomography (OCT) is one of the most rapid developing technologies in ophthalmology. OCT angiography (OCTA) has been made possible by the development of even faster scanning and sampling techniques, which is the next milestone after stratus OCT and spectral domain OCT. Without the need of injection of the contrast agent, OCTA is capable of providing a three-dimensional reconstruction of the perfused microvasculature within the retina and choroid by detecting the motion of scattering particles such as erythrocytes within sequential OCT cross-sectional scans performed repeatedly at the same location of the eye with different analysis algorithms. Comparing to fundus fluorescein angiography and indocyanine green angiography, with improved OCT technology and understanding, OCTA has showed certain advantages to diagnose retinal and choroidal diseases, especially macular vascular diseases. It is important to establish the contributions that OCTA can make to diagnosing, managing and understanding of ocular fundus diseases.

Pectus excavatum and carinatum are the most common deformity of chest wall deformity.To get anatomical deformity correction,beautify,improve physical function and the quality of life are the therapeutic purposes.Among the various clinical research and treatment,non-invasive treatment,which is the trend,is popular in surgeons and patients as well.From clinical experience,combining international and domestic progress of treatment on chest wall deformity,this review discuss the application prospect of non-invasive treatment.

OBJECTIVE:To evaluate the cost-effectiveness of 4 different therapeutic regimens for cervicitis of chlamydia trachomatis.METHODS:4therapeutic regimens including regimen A(azithromycin by oral administration),regimen B(azithromycin by intravenous injection),regimen C(minocycline by oral administration),regimen D(levofloxacin and de?oxycycline by oral administration)were analyzed using cost-effectiveness analysis.RESULTS:The total costs of A,B,C,D4regimens were(645.20?109.56)yuan,(933.10?249.90)yuan,(413.14?38.04)yuan,and(489.00?83.60)yuan respective?ly;The effective rate were96.2%,98.6%,93.4%and94.1%respectively;The ratios of cost to effectiveness were6.71,9.46,4.42,and5.19respectively;As compared with regimen C,the incremental cost effectiveness ratios for regimen A,B and D were82.88,99.99,and108.37respectively.CONCLUSION:Regimen C is the preferable one.