1.Detecting Chromosome Aberrance of Oral Squamous Cell Carcinoma (OSCC) in Cytogenetics.
Journal of Medical Research 2006;0(02):-
Objective Detect chromosome aberrance(number and construction) in OSCC cell .Methods Cell were treated with colchicines and microsometic fluid, and then were expanded with cold acetic acid and formalized with methyl alcohol. After Giemsa staining, the cell were observed under oil microscope and the chromosome karyotype was analyzed. Results The number of OSCC chromosome is between 63~66, and many type of chromosome contruction is aberrant, chromosome break and monocase of chromosome break. The number change is appear in increasing of NO 1、7、16、19、20 and lose in NO 6、9、10、18、21、22, the constructing change in NO 1、2、4、11. Conclusion Analysising chromosome aberrance will be useful in location in chromosome for relative oncogene and suppressor gene.
2.Experimentul Study on Detecting the Infection Case of Ureaplasma Urealyticum
Journal of Medical Research 2006;0(04):-
Objective To analysis the infective case of Ureaplasma urealyticum(Uu)in women pregnancy system,in order to get evidence from medicine sensitive test in UU infection case.Method Use fluorescent quantitative PCR(FQ-PCR)to detect,then provide the medicine according UU-DNA value.After half month,apply the pills the patients stop medicine for 10 days to examine culture and sensitivity test.The positive patients is applied the medicine for half month,examine the UU-DNA after stopping medicine 10 days.Results After one treatment course,51.6% patients turn into negative in culture test.48.4% positive patients turn into negative after one medicine treatment course according to medicine sensitive result.Conclusion The FQ-PCR technique with culture and sensitivity test detect and treat infective case of UU combine is useful to clinical practice.
3.Advances on clinical application of non-absorbable antibiotic rifaximin
Chinese Journal of Clinical Infectious Diseases 2014;7(3):282-286
Rifaximin as a representative of the non-absorbable antibiotics,has special effects and wide application prospects in treatments of acute intestinal tract infections,irritable bowel syndrome,inflammatory bowel disease,diverticulosis of colon,hepatic encephalopathy and so on.This paper reviews the advances on clinical efficacy and safety of rifaximin to provide reference for clinical use.
4.Management strategies for effective organization of research in translational medicine in China
Chinese Journal of Medical Science Research Management 2011;24(3):151-153,159
As a new cross disciplinary study, translational medicine is expected to promote modern biomedical research to a new stage. In recent years, establishment of research structure of translational medicine has been completed or initiated in some areas where medicine is comparatively well developed, though this conduct is still at an exploratory stage. Referencing abroad experience,This paper discusses the innovative mechanisms and strategies for organization of traslational medicine with referrence to foreign expericences.
5.Studies on chemical constituents of Glycyrrhiza pallidiflora
Chinese Pharmaceutical Journal 1999;(1):11-
OBJECTIVE:To study the chemical constituents of Glycyrrhiza pallidiflora.METHOD:IR, 1 H-NMR,13C-NMR,MS and TLC were used to identify conpounds .RESULTS:Five compounds were elucidated as homopterocarpin,β-sitosterol,4',7-dimethoxyisoflavone,medicarpin and isoglabrol. CONCLUSION:The 4',7-dimethoxyisoflavone was first separated from this plant .
6.Association between ACE gene polymorphism and type 2 diabetic nephropathy
Ying KAN ; Yan ZHAO ; Xun KAN ; Cai LI
Journal of Jilin University(Medicine Edition) 2006;0(02):-
0.05).Conclusion There is no significant correlation between ACE gene polymorphism and type 2 diabetic nephropathy.
7.STUDY ON THE Th1/Th2 PROFILE IN PATIENTS SUFFERING FROM CONDYLOMA ACUMINATUM WITH OR WITHOUT GENITAL HERPES
Li LI ; Zaigao ZHOU ; Kan ZENG
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
To investigate the Th1/Th2 profile in peripheral blood of patients suffering from condyloma acuminatum (CA) with or without genital herpes. The levels of the intracellular cytokines (IFN ? and IL 4) of CD4 + T lymphocytes of peripheral blood were assayed by flow cytometry in 35 patients with CA (among them 15 patients were complicated by genital herpes) and 20 healthy volunteers as controls. The results showed that all the patients with CA had significantly higher percentage of Th2 cells and lower percentage of Th1 cells compared with heathy controls( P
9.Clinical Observation on 42 Cases of Infertility due to Toxoplasma Infection Treated by Qing Jing Chong Ji
Guangchong QI ; Qixin LI ; Qinlin KAN
Journal of Traditional Chinese Medicine 1993;0(10):-
After seminal fluid detected by polymerase chain reaction (PCR) in 42 cases of male infertility indicated Tox - DNA positive, and abnormal seminal fluid was confirmed by analysis of computered autonomic analyser, they received treatment of Qing Jing Chong Ji. After one therapeutic course, one month constituting one course, Tox - DNA transformed negative in 36 cases, negative -transforming rate being 85. 7%. After treatment of 2 courses, in 2 cases Tox -DNA tranformed negative, the negative -transforming rate being 4. 76%. The total negative - transformingrate was 90. 48%. Density of spermia, rate of sperm movement ahead, velocity of sperm movement, sperm number of rapid movement, mean longitudinally linear ratio, mean swing frequency of sperm head all improved markedly as compared with those before treatment (P
10.An Investigation on Job Burnout of Doctor and Nurse
Chaoping LI ; Kan SHI ; Zhengxue LUO
Chinese Journal of Clinical Psychology 2001;0(03):-
Objective:To investigate job burnout status of doctor and nurse in China. Methods: 218 doctors and nurses were assessed by MBI-HSS. Results: 42.1% subjects got high or moderated scores on Emotional Exhaustion, 22.7% subjects got high or moderate scores on Depersonalization and 48.6% subjects got low or moderate scores on personal accomplishment. Female subjects got higher scores on Emotional Exhaustion than male subjects Compared with.subjects with higher level education, subjects with lower level education got higher scores on Emotional Exhaustion, however, lower scores on Personal Accomplishment.Conclusion:Some subjects are found to experiences job burnout. To prevent or cure job burnout, more attention should be paid to female and persons with lower level education.