Objective To discuss the effect of treating tubal obstruction infertility through hydrotubation by hysteroscopy combined with Chinese traditional medicine. Methods Chose 308 patients with tubal obstruction infertility from October 2001 to December 2008 and used the hysteroseopy under which making tubal cannulation, then injected methylene blue and clear liquid to record cases of tubal patency.After the operation the patients would be given Chinese traditional medicine and followed up the case of pregnancy. Result The recanalization rate in 308 patients was 90.9% (280/308), and the rate ofre-pregnancy was 55.5%(161/290). Conclusion The effect of treatment through hysteroscopy to make tubal cannulation and have patients take medicine after operation is very satisfactory and it is worth promoting.

〔Abstract〕 Taking PubReader as an example , the paper introduces typical applications of HTML 5 in displaying medical information . By cases in medical information display , it illustrates advantages of HTML 5 in interface alternation , intelligent terminal support , multime-dia presentation , and local storage , etc.It also predicts its future development tendency and disadvantages .

Objective To investigate the effect of blood pressure when measuring with clothing. Methods Measure the blood pressure of the right upper limb by using two different methods among the same group, and then analyze the data. Results Both SBp and DBp values which have measured with clothing are significant higher than those which have measured without clothing. The average difference of SBp and DBp are 1.54 mm Hg and 1.01 mm Hg respectively. Conclusion The patients who have no abnormal Bp history can be measured Bp with clothing, while this method should be forbidden to the patients who have hypertension or hypotension history.

The overuse of drugs and the irrational increase in medical expenses are currently hot social issues. Standards need to be set in a strict way so as to reasonably contain the cost of medical and health care and die prices of drugs and to lower the expenses of medical services. Analyses conducted in our hospital indicate that the component ratio of the drug income fell from 48.1% in January through June, 2001 to 38.7% one year later; the hospital's overall income in January through June, 2002 dropped 5.3% as compared with the same period of 2001, with the drug income dropping 23.7% and the medical treatment income rising 11.8%; the average expenses bom by emergency outpatients and discharged patients in January through June, 2002 both lowered as compared with the same period of 2001. The authors hold that the component ratio of the drug income ought to be a key index in assessing the integrated management Wei of a hospital; the proportion of the drug income in the overall income of a hospital ought to be restricted to 40% or so; and when general plans are being made for a hospital as a whole with regard to the proportion of the drug income, different standards ought to be set for various specialties.

Acute cartilage injury is one of the most common disorders in orthopaedic clinics.Articular cartilage is known to have a limited capacity to repair or regenerate itself. The disorder is difficult to be dealt with, usually affects the function of joint and may induce the onset of osteoarthrosis.This will result in great economic burdens on the patients and their family and greatly degrade the patient s quality of life. The recent progress in researches on seed cells, culture methods, biological material has provided a new method to repair the acute injury of articular cartilage and thus may solve many problems. The article introduces new advances in seed cells and their culture methods in cartilage tissue engineering.

Epidemiological studies indicate that obesity is associated with metabolic disorders, such as type 2 diabetes hyperlipidemia and hypertension. Early nutrition, especially during pregnancy and lactation can lead to the permanent programming of system by some adaptive effects in physiological, cellular and molecular levels. These adaptive effects persistently changed the metabolic throughout life, hence resulted in increased risk of obesity and metabolic related disease.This review focuses upon the influence of nutrition in early life on adulthood obesity and researches on their pathophysiological mechanism .

Objective To study the effects of direct-current field stimulation on spinal cord motor neurons apoptosis after sciatic nerves transection. Methods In experimental group direct-current stimula tors were put into the relevant spinal cord segments and electric stimulation were given instantly after sciatic nervet ransection.In control group, the same st I mulator were put inside without courrent output.The spinal cord specimens were taken 1，4，7，14，28 days after operation. The morphology of the spinal cord motor neurons was observed with the methods of HE staining and light microscope.The spinal cord motor neurons were counted and analyzed with three-dimensional quantit ative method.The TUNEL staining of the specimens was performed simultaneously and the positive-stain spinal cord motor ne u rons were counted. Results 4，7，1 4 and 28 days af ter operation, the number of spinal cord motor neurons and the size of the neurons increased obviously with compare to the control group.The TUNEL staining positive spinalcord motor neurons decreased sign I ficantly according to the control group. Conclusion Direct-current stimu lation may have intervention effects on spinal cord neuron apoptosis after sciatic nerve transection.

The difference between absorption of unfractionated heparin (UFH) and low molecular weight heparin (LMWH) after oral and oral cavity administration were studied respectively, and the compatible enhancer for oral cavity delivery system of both drugs was found. The LMWH and UFH films were prepared with two bioadhesive materials Carbopol and alginate sodium for oral cavity delivery. The activated partial thromboplastin time (APTT) was used to determine LMWH and UFH in plasma after oral, oral cavity and sc administration in rats. The results show that the enhancer (Labrasol) can increase the absorption of LMWH and UFH through oral cavity in rats but not obviously. The oral cavity iontophoretic delivery system is a useful method to improve the absorption of LMWH and UFH through oral cavity mucosa.

BACKGROUND:In recent years, the use of chimeric antigen receptor modified T cells (CAR-T cells) has achieved good results in the treatment of hematological malignancies. OBJECTIVE:To summarize the CAR-T technology, and its anti-tumor mechamism, progress in the treatment of hematological malignancies as well as its safety and coping strategies. METHODS:A search of PubMed, CNKI, Wanfang by computer was performed for articles related to CAR-T published from January 2010 to January 2016, using the keywords of CAR-T in English and Chinese, respectively. RESULTS AND CONCLUSION:The main principles that CAR-T cells fight against tumors are as follows: (1) resistance to immune escape through down-regulation of MHC; (2) production of interleukin-6, -10 indirectly influences the growth of tumor cells; and (3) tumor microenvironment changes inhibit tumor growth. The use of CAR-T in the treatment of hematological malignancies has been developed by leaps and bounds in recent years. Current studies concerning B cell lymphoma mainly focus on anti-CD19 CAR-T cells that have certain therapeutic effects on acute myeloid leukemia and acute lymphoblastic leukemia. However, its safety and effectiveness have yet to be studied.

A fluorescence quenching method was established for the determination of H2 S in intestinal perfusate by optical fiber sensing technology combined with micro sequential injection lab_on_valve (μSIA_lov). In the experiment, 100 μL of 0. 1 mol/L NaOH was used as the carrier, and 50 μL of 5. 0×10-5 mol/L fluorescein mercury and 50 μL of sample were selected for the determination. The detection flow rate at the flowcell was 25 μL/s. According to H2 S quenching fluorescence at 521 nm, the concentration of H2 S in the sample was determined. The detected concentration range of H2S was 5. 0×10-6-8. 0×10-5 mol/L, and the detection limit was 5. 4×10-7 mol/L. Detection result of H2S in intestinal perfusion was 3. 8×10-5 mol/L with 3. 1% RSD (n=3). This method can be used for the determination of H2S effectively in the samples, which lay the foundation for real_time online measurement of H2 S in biological samples.