1.Analysis of relative factors for drug-induced hypoglycemia in elderly diabetic patients
Chinese Journal of Geriatrics 2014;33(2):163-165
Objective To analyze the risk factors for drug-induced hypoglycemia in elderly diabetic patients,and to provide the basis for clinical prevention and treatment.Methods 78 cases with drug-induced hypoglycemia in elderly diabetic patients (observation group) and 256 elderly diabetic patients without drug-induced hypoglycemia(control group) were included,and the relative factors for drug-induced hypoglycemia were analyzed between the two groups.Results The stable rate of patient's condition was lower in observation group than in control group [38.5% (30/78) vs.52.7%(135/256),x2 =4.872,P<0.05].There were 9 cases (11.5%)、with alimentary control,28 cases (35.9%) treated with insulin and 41 cases (52.6%) treated with sulfonamide in observation group,and 89 cases (35.9%) with alimentary control,89 cases (34.8%) treated with insulin and 78 cases (30.4%) treated with sulfonamide in control group.The alimentary control was lower in observation group than in control group(x2 =15.557,P<0.001).There was no difference in successful rate of insulin treatment between the two groups(x2 =0.034,P>0.05).The successful rate of sulfonamide treatment was higher in observation group than in control group(x2 =12.726,P< 0.001).The age was older in observation group than in control group(t=2.494,P<0.01).The body mass indexes and glycosylated hemoglobin level were lower in observation group than in control group(t=4.334 and 7.251,both P<0.001).There were no differences in fasting blood-glucose and serum creatinine levels between the two groups(t=1.010 and 0.297,both P>0.05).The course of diabetes was longer in observation group than in control group(t=2.579,P<0.01).Conclusions The relative factors for drug-induced hypoglycemia in elderly diabetic patients include older age,longer course of diabetes,lower body mass index,lower fasting blood-glucose level,poorer glycemic control and higher dose of sulfonamide treatment.
2.Hospital-acquired Pneumonia:Risk Factors and Antimicrobial-resistant Gram-negative Bacilli in Adult Patients
Chinese Journal of Nosocomiology 2006;0(09):-
OBJECTIVE To know the incidence, etiology, risk factors of hospital-acquired pneumonia(HAP). METHODS From Jan 2003 to Dec 2004, 129 cases of HAP were retrospectively studied. Epidemiologic data, etiology , and evolution of pneumonia were recorded. RESULTS The 115 patients with HAP had one or more intrinsic risk factors, mainly malnutrition (albumin values
3.Research progress in screening of early esophageal cancer in China
Chinese Journal of Thoracic and Cardiovascular Surgery 2021;37(1):52-58
China is a country with high incidence of esophageal cancer. Precision screening and early diagnosis of esophageal cancer is the premise and key of precise treatment, and also an effective measure to improve the prognosis of esophageal cancer; The mode of combining key screening of high risk groups with screening of opportunistic individual, endoscopy assisted with iodine staining and indicative biopsy is feasible strategy and effective method to screen early esophageal cancer in the stage. Artificial intelligence and molecular biology technology is the research direction and has the development prospect.
4.The management of facial nerve tumor manifested as facial paralysis.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;29(8):716-719
OBJECTIVE:
To heighten the awareness of the facial nerve tumors.
METHOD:
The clinical data of twenty-three patients complaining of facial paralysis who were diagnosed postoperatively as facial nerve tumors were analyzed. The hearing assessment of all patients was based on pure tone audiometry at the frequency of 0. 5, 1, 2, 4 kHz. Temporal bone high resolution CT scan and temporal bone MRI with gadolinium enhancement were conducted on all patients. Facial nerve function was assessed with the House-Brackmann (HB) grading system. Facial electroneurography (ENoG) was conducted on 20 patients to quantify the degree of nerve degeneration preoperatively. The pathological types of tumor were determined by postoperative pathological reports.
RESULT:
Nineteen out of 23 cases presented hearing loss (82.6%), 10 cases suffered from tinnitus (43.5%), otalgia (17.4%) affected 4 cases, 3 cases manifested otorrhea (13.0%), and 2 cases presented vertigo (8.7%). Geniculate ganglion was the most commonly involved site (20 cases, 87.0%), followed by tympanic segments (18 cases, 78.3%), pyramid segment (16 cases, 69.6%), mastoid segment (10 cases, 43.5%), labyrinthine segment (9 cases, 39.1%), internal auditory canal segment and parotid gland segment (5 cases, 21.7%, respectively). Twenty-one cases (91.3%) of schwannomas, 1 case (4.3%) of neurofibroma and 1 case (4.3%) of hemangiomas were identified with histopathology postoperatively. The tumors were all completely excised, and the facial nerve function could recovered to HB III at the best after facial nerve repairment.
CONCLUSION
Facial nerve tumor is a rare and often misdiagnosed disease which was commonly manifested as facial nerve paralysis. Temporal bone CT and MRI can help to clarify the diagnosis preoperatively. Pure tone audiometry and electroneurography also plays a some certain roles in the diagnosis of facial nerve tumors. The tumors should be completely resected and the surgical approaches were determined based on tumor size, facial nerve function and preoperative auditory function.
Cranial Nerve Neoplasms
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complications
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Facial Nerve
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pathology
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Facial Nerve Diseases
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complications
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Facial Paralysis
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etiology
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Hearing Loss
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Hemangioma
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Humans
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Neurilemmoma
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Temporal Bone
5.Investigation and Analysis of Present Staff Situation in Teaching Hospitals
Chinese Journal of Medical Education Research 2002;0(01):-
This article reveals the present state of teaching staff in teaching hospitals and difficulties and obstacles the hospitals confront when conducting the clinical courses through the investigation and analysis of 6 teaching hospitals.It provides a very useful reference for teaching hospitals in term of expanding their teaching resources and carrying out staff training.
6.The Emotion Burnout and Sound Personalities of the University Students
Chinese Journal of Medical Education Research 2005;0(05):-
The university students must promote themselves to become persons with sound personality in order to adapt to the society request for talents.But the university students experience emotion burnout and the deviation of development in mental and behavior during the period full of variety and surging.So the education of sound personality should be placed in the higher education to raise the university student's comprehensive character.
7.Approach to Medical English Curriculum Development
Chinese Journal of Medical Education Research 2006;0(11):-
To expatiate upon the characteristics of systematization and refinement in medical English curriculum planning,to visualize the developing strategies of curriculum construction,and trying to probe into the formula in medical English teaching and learning.
8.Training of Endoscopic Surgery in Medical Undergrauates
Chinese Journal of Medical Education Research 2006;0(07):-
This article evaluates the necessity and possibility of endoscopic surgery training in medical undergraduates and designs a simple,suitable platform and exercise for the training.
9.Determination and clinical significance of serum hypersensitivity C-reactive protein and hypersensitivity cardiac troponin in patients with coronary heart disease
Chinese Journal of Primary Medicine and Pharmacy 2013;20(12):1814-1816
Objective To research the determination of hypersensitivity C-reactive protein(Hs-CRP) and cardiac troponin T(Hs-cTnT) in patients with coronary heart disease,and to analyze the correlation with cardiac function.Methods The function of left ventricle and the serum levels of Hs-CRP and Hs-cTnT in 100 patients with coronary heart disease and 50 healthy subjects were detected.Results The function of left ventricle and the serum levels of Hs-CRP and Hs-cTnT were significantly different in patients with coronary heart disease and healthy subjects(P <0.01).The function of left ventricle and the serum levels of Hs-CRP and Hs-cTnT were significantly different in coronary heart disease patients with different New York Heart Association class(P < 0.01).The serum levels of Hs-CRP and Hs-cTnT were positively correlated with class of New York Heart Association,left ventricular end diastolic diameter,and negatively correlated with left ventricular ejection fraction and fraction shortening (Absolute value of r:0.536 ~ 0.849,P < 0.05).Conclusion The serum levels of Hs-CRP and Hs-cTnT significantly increase in patients with coronary heart disease,which is correlated to function of left ventricle,and it can be used as the indicators of cardiac function in patients with coronary heart disease.
10.Comparison of the effect of different local anesthetic epidural anesthesia for cesarean section
Chinese Journal of Primary Medicine and Pharmacy 2011;18(13):1772-1773
Objective To investigate the clinical effect of different local anesthetic epidural anesthesia for cesarean section. Methods 60 maternal intended to be carried out cesarean section by epidural anesthesia were randomly divided into two groups. A group(n =30 cases) was administrated with 0.5% ropivacaine to anesthesia,and B group(n = 30 cases) was administrated with 0. 5% bupivacaine to anesthesia. The changes of hemodynamic were monitored,and the analgesic effect and adverse reactions were observed in the two groups. Results The differences of blood pressure, heart rate had no statistical significance between the two groups (all P>0.05);Compared to B group, the anesthesia onset time, anesthesia time between the start of fetus, analgesic effect, adverse reactions of A group were significantly different (t = 4. 347,4. 528, x2 = 3. 834, 6. 429, all P < 0. 05 ) ; Neonatal Apgar score showed no significant differences between the two groups ( P > 0. 05 ). Conclusion Anesthesia with 0.5% ropivacaine for cesarean section had satisfactory anesthesia effect,and less adverse reactions.