1.Practice of Live Television Technique in the Teaching of Dental Implantation Surgeries
Chinese Journal of Medical Education Research 2003;0(03):-
With the development of surgical techniques in dental implantation, traditional teaching methods can not keep pace with the developing teaching situations.To resolve this problem,the live television technique has been applied in the teaching of dental implant surgery.The practice of live television technique not only stimulates students' learning interests,but also turns the passive education model into an interactive model with better teaching results.
2.Effect of ischemic preconditioning on the apoptosis of hepatocytesand expression of HIF-1? and Survivin in rats
Chinese Journal of Current Advances in General Surgery 1999;0(04):-
Objective:To observe the effect of ischemic preconditioning(IP)on hepatocellular apoptosis caused by ischemia-reperfus ion(IR)injury and expression of apoptosis regulatory genes(Survivin,HIF-1?)protein,to explore the protective mechanisms of IP on IR injury in rat liver.Methods:Ninty SD rats were randomly divided into sham operation(SO)group,ischemia-reperfusion(IR)group,ischemic preconditioning(IP)group.In SO group,the hepatoduodenal ligament of rat was only pulled and separated,and then closed the abdomen;IR group subjected to 30 minutes of ischemia;IP group was achieved by ischemia for 5 minutes,followed by reperfusion for 5 minutes before continuous to ischemia for 30 minutes.Ten rats of each group were killed after reperfusion for 2,6,12,24 hours respectively,then liver tissues were taken out.The rats in SO group were killed after operation for 2 hours.To detect the Apotosis index(A)Iand Survivin,HIF-1? protein levels.Results:AI of hepotocytes significantly increased in IR group and IP group than that in SO group(P
3.Large mixed tumors of salivary: two cases reports.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(21):1714-1715
It is rare that large mixed tumors of salivary gland located in the nose and uvula. The patient who had mixed tumors of salivary gland at nose found exophytic growth tumor for half a year. The other patient who had mixed tumors of salivary gland at uvula felt swallowing foreign body sensation for one year, and dysphagia for one month. After surgical resection, the symptoms disappear.
Adenoma, Pleomorphic
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complications
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pathology
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Deglutition
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Deglutition Disorders
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etiology
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Humans
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Nose Neoplasms
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pathology
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Palatal Neoplasms
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pathology
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Salivary Gland Neoplasms
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complications
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pathology
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Uvula
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pathology
4.Association between platelet distribution width and heart failure due to coronary heart disease
Bin LI ; Kun WANG ; Gang ZHENG
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2017;19(6):569-572
Objective To study the association between platelet distribution width (PDW) and other indexes in coronary heart disease (CHD) patients with heart failure (HF).Methods Five hundred and ninety-one CHD patients with HF were divided into control group with their NT-proBNP<300 ng/L (n=228),mild HF group with their NT-proBNP=300-3000 ng/L (n=191),and severe HF group with their NT-proBNP>3000 ng/L(n=172).Their blood and echocardiographic parameters were recorded.Results The PDW was significantly shorter in 3 groups after treatment than before treatment (0.129±0.031 vs 0.133±0.027,0.133±0.030 vs 0.141± 0.029,0.139±0.028 vs 0.148±0.029,P<0.05,P<0.01),and was significantly longer in mild HF group and severe HF group than in control group and in severe HF group than in mild HF group after tgreatment (P<0.05,P<0.01).Multivariate stepwise regression analysis showed that PDW was positively associated with NT-proBNP and LAD (P=0.001,P=0.000) and negatively associated with LVEF (P=0.003).Conclusion PDW increases with the severity of HF in CHD patients and can thus play an auxiliary role in assessing the severity of their HF.
5.Effect of patient-controlled intravenous analgesia with dexmedetomidine mixed with sufentanil on sleep quality after spinal surgery
Kun WANG ; Chengwen LI ; Hongtu WEI
Chinese Journal of Anesthesiology 2015;35(10):1224-1227
Objective To investigate the effect of patient-controlled intravenous analgesia (PCIA) with dexmedetomidine mixed with sufentanil on the sleep quality after spinal surgery.Methods Eighty patients of both sexes, aged 21-72 yr, weighing 48-100 kg, of American Society of Anesthesiologists physical status Ⅰ or Ⅱ , scheduled for elective spinal surgery, were randomly assigned into sufentanil group (group S) and dexmedetomidine mixed with sufentanil group (group DS) with 40 cases in each group.In group S, PCIA solution contained sufentanil 2 μg/kg and tropisetron 6 mg in 100 ml of normal saline.In group DS, PCIA solution contained sufentanil 2 μg/kg, dexmedetomidine 3 μg/kg and tropisetron 6 mg in 100 ml of normal saline.The PCA pump was set up with a 0.5 ml bolus dose, a 15 min lockout interval and background infusion at a rate of 2 ml/h.Sufentanil 5 μg injected intravenously and celecoxib 200 mg given orally were used as rescue analgesics, and numeric rating scale (NRS) score at rest was maintained ≤4 within 48 h after surgery.Ramsay sedation scores were recorded at 1, 2, 6, 12, 24 and 48 h after surgery.Sleep quality was evaluated using the Medical Outcomes Study Sleep Scale (MOS-SS), and the average time of daily sleep and Sleep Problems Index (SPI) were recorded at week 1 before and after surgery.Patient's satisfaction with sleep was assessed on the night of surgery and 1st day after surgery.The requirement for rescue analgesics was recorded.Results There was no significant difference in the requirement for rescue analgesics between group S and group DS (P>0.05).Compared with the value before surgery, the average time of daily sleep was significantly shortened, and SPI was increased at week 1 after surgery in group S (P<0.05 or 0.01), and no significant change was found in group DS (P>0.05).Compared with group S, the Ramsay sedation scores were significantly increased at 1, 2, and 6 h after surgery, the average time of daily sleep was prolonged at week 1 after surgery, the SPI was decreased at week 1 after surgery, and the degree of satisfaction with sleep was increased on 1st day after surgery in group DS (P<0.05 or 0.01).Conclusion PCIA with dexmedetomidine mixed with sufentanil is helpful in improving the sleep quality after spinal surgery in the patients.
6.Reliability and Validity of Chinese Version of Comprehensive Frailty Assessment Instrument
Kun WANG ; Changxiang CHEN ; Shuxing LI
Chinese Journal of Rehabilitation Theory and Practice 2017;23(1):72-76
Objective To translate the English version of Comprehensive Frailty Assessment Instrument (CFAI) into Chinese and evalu-ate its reliability and validity. Methods CFAI was translated into Chinese with the Brislin's translation mode. From May to July, 2015, 200 community aged people in Shijiazhuang, China were assessed with the Chinese version of CFAI and World Health Organization Quality of Life-BREF (WHOQOL-BREF), and 30 of them were assessed with CFAI again after a week. The content validity was rated by six experts of gereology. The total scores of CFAI and WHOQOL-BREF were analyzed with Pearson's correlation, as well as the scores of CFAI test and retest. The CFAI were analyzed with Factor Analysis. The Cronbach's α was tested. Results There were 23 items in 4 dimensions. The content validity index was 0.782. Six factors were extracted by Factor Analysis and the cumulated variance was 64.05%. The total score of CFAI correlated with the score of WHOQOL-BREF (r=-0.764, P<0.001). The Cronbach's α was 0.704~0.897 in dimensions (P<0.001), and the r= 0.604~0.941 (P<0.001) between test and retest. Conclusion The Chinese version of CFAI is reliable and valid, that can be applied to evaluate frailty in community aged people.
7.Cyclic mechanical stretch influences cell adhesion and spreading of immortalized human keratinocytes
Kun LIU ; Meiwen AN ; Li WANG ; Jingjing HUANG
Chinese Journal of Tissue Engineering Research 2015;(1):119-123
BACKGROUND:The mechanical environment of skin tissue and spreading state of epithelial cels are closely related with the wound healing and scar formation process. OBJECTIVE:To analyze the effect of extracelular mechanical stimulation on cel spreading, to test the cel proliferation in order to analyze the effect of spreading form on cel proliferation and other physiological activities. METHODS: Cyclic sine wave mechanical stretching was exerted on immortalized human keratinocyte by using FX-4000 flexible substrate loading system, on the condition of 0.2 Hz and at frequency of 10% amplitudes. The spreading form was compared at 0, 24 and 48 hours, the cel proliferation was analyzed with flow cytometry, and the distribution of vinculin was analyzed with immunofluorescence staining. RESULTS AND CONCLUSION: human keratinocyte would keep the spreading state and could induce more cel proliferation by 24 hours mechanical stretching stimulation. Conversely, after stimulated for 48 hours, the morphology of the human keratinocyte was significantly changed, and the number of human keratinocyte in the division stage was larger than that in the static control group; under tensile stress, the distribution of vinculin was transformed from the surrounding nucleus membrane area to the cel edge. The results indicate that proper mechanical stimulate can increase cel proliferation with keeping cel spreading and adhesion state; the stimulating time of continuous cyclic stretching is the major factor to determine cel spreading morphology and adhesion regions of immortalized human keratinocyte.
8.Influence of bicortical anchorage on the natural frequency of the dental implant
Kun WANG ; Dehua LI ; Jingyu YU
Journal of Practical Stomatology 2001;0(03):-
Objective:To investigate influences of bicortical anchora ge on the values of natural frequency of dental implants. Methods: Using the commercial code of SolidWorks, 3-D models of a screw-shaped dental i mplant and a mandibular bone segment were generated. After the 3-D implant-bon e complex was meshed by ABAQUS software, effects of bicortical anchorage on the buccolingual and axial first-order natural frequencies of the implant were comp uted. Results:Bicortical anchorage increased the buccolingual na tural frequencies and the axial natural frequencies of the implants by a maximu m of 13.77% and 107.40% respectively. The apical anchorage depth in the cortical bone had an insignificant effect on further increase of implant stability. Conclusion:Bicortical anchorage can increase the stability of dental implants, especially in the axial direction.
9.CT Diagnosis of Lymph Node Reactive Hyperplasia
Yingying DING ; Kun LI ; Yongping WANG
Journal of Practical Radiology 2001;0(05):-
Objective To analyze CT features and CT diagnostic value in lymph node reactive hyperplasia.Methods CT findings of lymph node reactive hyperplasia in 13 cases proved surgically and pathologically were retrospectively analyzed.Results Of 13 cases,7 cases were only involved cervical lateral lymph nodes,2 cases were simultaneously involved cervical lateral,facial and submental lymph nodes,1case was involved axillary and inguinal lymph nodes,1 case demonstrated simultaneously enlarged in cervical,axillary,mediastinal,retroperitoneal and inguinal lymph nodes.Enlarged lymph nodes ranged from 0.6 to 2.6 cm in minimal diameter.with mean of 1.6 cm.Lymph nodes enlaged showed isolated existence in 12 cases,merely 1 case mixed existence and the density was unhomogeneous,12cases showed homogeneous density and obvious enhancement on postcontrast CT,and CT value increased by 19.1~113.2 HU,with mean of 59.1 HU.Conclusion Lmyph node reactive hyperplasia is of characteristic CT appearances,CT examinations is of important value for its qualitative and differential diagnosis.
10.Relation of hepatitis C virus level and genotypes to response to interferon treatment
Kun LI ; Lihui WANG ; Jun YE
Chinese Journal of Practical Internal Medicine 2000;0(12):-
Objective To investigate the relationship between HCV genotype and its level and the response to interferon (IFN).Methods HCV genotypes were detected by type-specific primes modified PCR assay.HCV-RNA levels were determined by branched DNA(bDNA) singnal PCR amplification fluorescence assay.The patients with chronic hepatitis C virus infection treated with IFN ? were divided into different groups according to genotypes or levels of HCV.Result Patients with pre-treatment HCV levels10 9 eq?L -1 showed partial responses (28 6%) or no responsces (28 6%).Stasistical analysis showed significant difference (P