Objective:To study a set of system for supplying oxygen monitoring and control in networking. Methods: Oxygen monitoring devices, which are laid up the entrance of clinical department, include signal monitoring and control. Electromechanical actuator consists of oxygen valve and oxygen solenoid valve;Sensor group consists of a pressure sensor, an oxygen concentration sensor and a gas flow sensor;The design circuit includes signal acquisition and data processing, communication and the master circuit board, oxygen dedicated solenoid valve control driver circuit board. Results:The center monitoring technology for oxygen supplying in hospital can monitor oxygen pressure, concentration and flow of all clinical departments. Meanwhile, the monitoring center can be timely warned when oxygen pressure and concentration are lower than normal value. If firing appeared in ward, oxygen supplying can be closed by remote automatic or manual oxygen monitoring control device. Conclusion:This monitoring system can ensure quality and security of oxygen supply, and achieve remote monitoring and alarm of oxygen supply, and improve the level of oxygen supply management.

Recently,with the development of the medical technique includes surgery,radiotherapy,chemotherapy and molecular targeted therapy,multi-subject combined modality therapy for esophageal carei noma has been become a tendency instead of surgery alone.Any single treatment is hard to improve the curative effect of treatment for esophageal carcinoma.Systemic individual comprehensive therapy for the different patients with esophageal carcinoma is likely to reduce recurrence rate,improve survival rates as well as to improve the quality of life.

Adult ; Animal Experimentation ; Female ; Hemorrhagic Fever with Renal Syndrome ; etiology ; Humans ; Male ; Medical Laboratory Personnel ; Middle Aged

0. 05), respectively. Conclusion: Repeated +Gz stress may disorder the ratio of ET and NO. This imbalance may be one of the causes which lead to pathology changes in masseter musscles.

Objective To explore the relationship among the severity of coronary disease, c-reaction protein (CRP) and mild renal dysfunction. Methods 64 patients underwent coronary angiography were divided into two groups according to their serum creatinine (cr) levels: normal renal function(cr

Excessive and fast rise of medical expenses in China recent years has worsened the financial burden of both the government and individuals alike,making it a hotspot issue countrywide.To alleviate the difficulties of "accessibility to medical services" and "poverty or repoverty resulting from sickness" faced by the Chinese people at large,we built a multi-factor analysis model to identify key factors contributing to such a fast rise of medical expenses based on an analysis of the medical expenses in Shandong Province.In addition,we discussed the causes for GDP and headcount of medical staff in relation to the rise of medical expenses,and the strategies to curb expenses.

Objective To explore the role of the medical engineering department in integration of the health care,nursing and medical technology departments.Methods The medical engineering department and integration of health care,nursing and medical technology departments were introduced from the aspects of concept,role,characteristic,working mode and etc.Results The medical engineering department contributed to enhancing medical service,medical safety and patient satisfaction,while the role needed strengthening.Conclusion Some measures are put forward to the medical engineering department during integration of health care,nursing and medical technology departments from the aspects of department positioning,examination and assessment,management mode and etc.

Objective To construct the eukaryotic expression vector encoding IT15 gene and detect its expression in SH-SY5Y cells.Methods The exon1 of IT15 gene was amplified from genomic DNA isolated from a healthy adult and a Huntington disease patient lymphoblastoid cell lines by PCR.PCR products were subcloned into eukaryotic expression vector pEGFP-C1.The SH-SY5Y cells were transiently transfected with the recombinant plasmids and observed under fluorescence microscope.Western blot was used to detect the expression of the fusion protein.Results PCR products had approximately 170 and 310 bp specific segments.The recombinant eukaryotie expression plasmids were confirmed by restriction endonuclease analysis and sequencing.The N-terminal fragment of normal huntingtin primarily localized in the cytoplasim of SH-SY5Y cells,while the N-terminal fragment of mutant huntingtin aggregated both perinuclearly and intranuelearly.Conclusions The recombinant eukaryotic expression vectors encoding wild type and mutant IT15 gene fragments are useful for studying pathogenesis of Huntington disease.The Nterminal fragment of mutant huntingtin aggregats both perinuclearly and intranuclearly,which could be important for Huntington disease pathophysiology.

Objective To determine the sensitivity and specificity of anti-cyclic citrullinated peptide antibodies (anti-CCP antibodies) in the diagnosis of rheumatoid arthritis. Method A total of 1018healthy donors, 212 patients with rheumatoid arthritis, 435 patients with other connective tissue disease were recruited to this study. Anti-CCP antibodies and IgM-rheumatoid factor (RF) were determined by ELISA according to manufacturer instructions, with a cut-off of 20U. Result The frequency of positive anti-CCP antibodies in patients with rheumatoid arthritis is 48.1% (n = 102 ), higher than healthy donors (2.6%,n = 26) and patients with other connective tissue diseases (3.7%, n = 16). The specificity of anti-CCP antibodies is 97.4%. The titer of anti-CCP antibodies in patients with rheumatoid arthritis (429. 7 U) is much higher than that in healthy donors (29. 3 U ) and patients with other connective tissue diseases (36. 5 U). The frequency of positive IgM-RF in patients with rheumatoid arthritis is 94. 3% whilst only21.5% in healthy donors. The false positivity rate of IgM-RF is higher than anti-CCP antibody. Conclusion Anti-CCP antibodies is a highly specific autoantibody in the diagnosis of rheumatoid arthritis.

Objective To explore the role of monitoring the cellular immune function in preventing and treating the fungal infection in the recipients of liver transplantation. Methods 679 cadaveric liver transplantations (from Jan. 2004 to Jan. 2010) were retrospectively studied. All the cases were divided into 3 groups according to different treatments and preventing regimens. The patients in groups A, B, C were treated based on the clinical experiences (394 cases), T lymphocyte subsets counting (151 cases), and combination of ATP values of CD4+ T cell and T lymphocyte subsets counting (134 cases), respectively. The infection, mortality and acute rejection rate were analyzed. The relationship between fungal infection and cellular immune function was investigated.Results The fungal infection rate in groups A, B, and C was 28. 9 %, 21.2 %, and 19. 4 % (P<0. 05), the morbidity rate was 16. 7 %, 12. 5%, and 3. 8% (P>0. 05), and the acute rejection rate was 28. 4 %, 17. 2 %, and 13. 4 % (P<0. 01), respectively. The CD4+ T lymphocyte counting in all cases of fungal infection was (147±43)×106/L. The morbidity could reach 50. 0 % when the CD4+ T lymphocyte counting < 100 ×106/L, while it was 2. 4 % when the counting was between (100-200) ×106/L (P<0. 01). The CD4+ T lymphocyte counting had no linear relation with the ATP value.The ATP value in fungal infection cases was (117 ± 61)μg/L. Conclusion The cellular immune function test could be quantitatively evaluated according to the T lymphocyte subsets and ATP value of CD4+ T lymphocyte. And individualized immunosuppressive therapy could be adjusted accordingly.Therefore, cellular immune function could be instructive in preventing and treating the fungal infection after liver transplantation.